Degradation of Alzheimer's β-amyloid protein by human cathepsin D

NeuroReport

Volumn 7, Issue 13, 1996, Pages 2163-2166

  McDermott, John R ^a   Gibson, Alison M ^a  

^a NEWCASTLE GENERAL HOSPITAL   (United Kingdom)

Author keywords

Alzheimer's disease; Cathepsin D; Human brain; Amyloid protein

Indexed keywords

AMYLOID BETA PROTEIN; CATHEPSIN D; PROTEINASE;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

EID: 0029804989     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-199609020-00021     Document Type: Article

References (19)

1. Glenner GG and Wong CW. Biochem Biophys Res Commun 120, 885-890 (1984).
2. Masters CL, Simms G, Weinman NA et al. Proc Natl Acad Sci USA 82, 4245-4249 (1985).
3. Haass C, Schlossmacher MG, Hung AY et al. Nature 359, 322-325 (1992).
4. Seubert P, Vigo-Pelfrey C, Esch F et al. Nature 359, 325-327 (1992).
5. Shoji M, Golde TE, Ghiso J et al. Science 258, 126-129 (1992).
6. Haass C, Hung AY, Citron M et al. Arzneim-Forsch./Drug Res 45, 398-402 (1995).
7. Haass C, Hung AY, Schlossmacher MG et al. J Biol Chem 268, 3021-3024 (1993).
8. Ladror US, Snyder SW, Wang GT et al. J Biol Chem 269, 18422-18428 (1994).
9. Evin G, Cappai R, Li QX et al. Biochemistry 34, 14185-14192 (1995).
10. Schwagerl AL, Mohan PS, Cataldo AM et al. J Neurochem 64, 443-446 (1995).
11. Bernstein HG, Brusziz S, Schmidt D et al. J Hirn Forsch 30, 613-618 (1989).
12. McDermott JR and Gibson AM. Neurochem Res (in press).
13. McDermott JR and Gibson AM. Identification and characterization of central nervous system peptidase activities. In: Smith Al, ed. Peptidases and Neuropeptide Processing. London: Academic Press, 1995: 281-295.
14. Bradford MM. Anal Biochem 72, 248-254 (1976).
15. Snyder DS, Simonis S, Uzman BG et al. J Neurocytol 14, 579-596 (1985).
16. Bohley P and Seylen PO. Experentia 48, 151-157 (1992).
17. Compaine A, Schein JD, Tabb JS et al Neurochem Int 27, 385-396 (1995).
18. Jarrett JT, Berger EP and Lansbury PT. Biochemistry 32, 4693-4697 (1993).
19. Munger JS, Haass C, Lemere CA et al. Biochem J 311, 299-305 (1995).