NS3 protein of hepatitis C virus regulates cyclooxygenase-2 expression through multiple signaling pathways

Virology

Volumn 371, Issue 1, 2008, Pages 61-70

  Lu, Lili ^a   Wei, Liang ^a   Peng, Guiqing ^a   Mu, Yongxin ^a   Wu, Kailang ^a   Kang, Lei ^a   Yan, Xiaohong ^a   Zhu, Ying ^a   Wu, Jianguo ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Cyclooxygenase 2; ERK; Gene regulation; Hepatitis C virus; Inflammation; JNK; NS3 protein; Pathogenesis; PKC; Signaling pathway; Virus infection

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NONSTRUCTURAL PROTEIN 3;

ARTICLE; GENE CONTROL; HEPATITIS; HEPATITIS C VIRUS; LIVER CELL CARCINOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

CALCIUM; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CYCLOOXYGENASE 2; DINOPROSTONE; GENE EXPRESSION REGULATION; GENES, REPORTER; HEPACIVIRUS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER NEOPLASMS; LUCIFERASES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NF-KAPPA B; PROMOTER REGIONS (GENETICS); PROTEIN KINASES; RNA, MESSENGER; SIGNAL TRANSDUCTION; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS;

EID: 37849052306     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2007.09.025     Document Type: Article

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