Nucleocapsid protein of SARS-CoV activates the expression of cyclooxygenase-2 by binding directly to regulatory elements for nuclear factor-kappa B and CCAAT/enhancer binding protein

International Journal of Biochemistry and Cell Biology

Volumn 38, Issue 8, 2006, Pages 1417-1428

  Yan, Xiaohong ^a   Hao, Qian ^a   Mu, Yongxin ^a   Timani, Khalid Amine ^a   Ye, Linbai ^a   Zhu, Ying ^a   Wu, Jianguo ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Cyclooxygenase 2; Gene regulation; Inflammation; N protein; Pathogenesis; SARS CoV; Virus infection

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NUCLEOCAPSID PROTEIN; VIRUS PROTEIN;

ARTICLE; BINDING SITE; CELL STRAIN HEK293; EMBRYO; ENZYME ACTIVATION; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INFLAMMATION; LUNG INJURY; MAMMAL CELL; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; PNEUMONIA; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SARS CORONAVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; BINDING SITES; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CYCLOOXYGENASE 2; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTATION; NF-KAPPA B; NUCLEOCAPSID PROTEINS; PLASMIDS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; SARS VIRUS; TRANS-ACTIVATION (GENETICS);

MAMMALIA; SARS CORONAVIRUS;

EID: 33646168070     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2006.02.003     Document Type: Article

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