Spike protein of SARS-CoV stimulates cyclooxygenase-2 expression via both calcium-dependent and calciumin-dependent protein kinase C pathways

FASEB Journal

Volumn 21, Issue 7, 2007, Pages 1586-1596

  Liu, Mo ^a   Yang, Yongbo ^a   Gu, Chunfang ^a   Yue, Yinpu ^a   Wu, Kenneth K ^b   Wu, Jianguo ^a   Zhu, Ying ^a  

^a WUHAN UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

COX; SARS CoV; Spike protein; Transcriptional activation

Indexed keywords

CALCIUM; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C ALPHA; PROTEIN SPIKE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS PROTEIN; VITRONECTIN;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; GENETIC SCREENING; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SARS CORONAVIRUS; SIGNAL TRANSDUCTION; VIRUS GENE;

ANIMALS; BASE SEQUENCE; CALCIUM; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; CYCLOOXYGENASE 2; DNA PRIMERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; MEMBRANE GLYCOPROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN KINASE C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SARS VIRUS; TRANS-ACTIVATION (GENETICS); VIRAL ENVELOPE PROTEINS;

SARS CORONAVIRUS;

EID: 34247629510     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.06-6589com     Document Type: Article

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