Somatic selection for and against cancer

Journal of Theoretical Biology

Volumn 225, Issue 3, 2003, Pages 377-382

  Michor, Franziska ^a   Frank, Steven A ^b   May, Robert M ^c   Iwasa, Yoh ^d   Nowak, Martin A ^a  

^a HARVARD UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

Evolutionary dynamics; Genetic instability; Mathematical model; Oncogenes; Tumor suppressor genes; Tumorigenesis

Indexed keywords

CANCER; SELECTION;

ANIMAL; APOPTOSIS; ARTICLE; BIOLOGICAL MODEL; CANCER INHIBITION; CANCER PREVENTION; CANCER RISK; CARCINOGENESIS; CELL COMPARTMENTALIZATION; CELL DIVISION; CELL PROLIFERATION; CYTOARCHITECTURE; GENE MUTATION; GENETIC DRIFT; GENETIC SELECTION; GENETICS; MICROSATELLITE INSTABILITY; MUTATION; NEOPLASM; ONCOGENE; PATHOLOGY; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 0242298209     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5193(03)00267-4     Document Type: Article

References (33)

1. Bach S.P., Renehan A.G., Potten C.S. Stem cells. the intestinal stem cell as a paradigm Carcinogenesis. 21:2000;469-476.
2. Bardelli A., Cahill D.P., Lederer G., Speicher M.R., Kinzler K.W., Vogelstein B., Lengauer C. Carcinogen-specific induction of genetic instability. Proc. Natl Acad. Sci. USA. 98:2001;5770-5775.
3. Breivik J., Gaudernack G. Carcinogenesis and natural selection. a new perspective to the genetics and epigenetics of colorectal cancer Adv. Cancer Res. 76:1999;187-212.
4. Breivik J., Gaudernack G. Genomic instability, DNA methylation and natural selection in colorectal carcinogenesis. Semin. Cancer Biol. 9:1999;245-254.
5. Cairns J. Mutation, selection and the natural history of cancer. Nature. 255:1975;197-200.
6. De Visser J.A.G.M. The fate of microbial mutators. Microbiology. 148:2002;1247-1252.
7. Ewans W.J. Population Genetics. 1969;Methuen, London.
8. Friend S.H., Bernads R., Rogelj S., Weinberg R.A., Rapaport J.M., Albert D.M., Dryja T.P. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature. 323:1986;643-646.
9. Giraud A., Radman M., Matic I., Taddei F. The rise and fall of mutator bacteria. Curr. Opin. Microbiol. 4:2001;582-585.
10. Jacobson M.D., Weil M., Raff M.C. Programmed cell death in animal development. Cell. 88:1997;347-354.
11. Kinzler K.W., Vogelstein B. The Genetic Basis of Human Cancer. 1998;McGraw-Hill, Toronto.
12. Knudson A.G. Mutation and cancer. statistical study of retinoblastoma Proc. Natl Acad. Sci. USA. 68:1971;820-823.
13. Komarova N.L., Lengauer C., Vogelstein B., Nowak M.A. Dynamics of genetic instability in sporadic and familial colorectal cancer. Cancer Biol. Ther. 1:2002;685-692.
14. Komarova, N.L., Sengupta, A., Nowak, M.A., 2003. Mutation-selection networks of cancer initiation: tumor suppressor genes and chromosomal instability, J. Theor. Biol., in press.
15. Kovacs L., Potten C.S. An estimation of proliferative population size in stomach, jejunum and colon of DBA-2 mice. Cell Tissue Kinet. 6:1973;125-134.
16. Lengauer C., Kinzler K.W., Vogelstein B. Genetic instability in colorectal cancers. Nature. 386:1997;623-627.
17. Levine A.J. The tumor suppressor genes. Annu. Rev. Biochem. 62:1993;623-651.
18. Levine A.J. p53, the cellular gatekeeper for growth and division. Cell. 88:1997;323-331.
19. Loeb L.A. Cancer cells exhibit a mutator phenotype. Adv. Cancer Res. 72:1998;25-56.
20. Loeb L.A., Springgate C.F., Battula N. Errors in DNA replication as a basis of malignant changes. Cancer Res. 34:1974;2311-2321.
21. Meier P., Finch A., Evan G. Apoptosis in development. Nature. 407:2000;796-801.
22. Michor, F., Iwasa, Y., Vogelstein, B., Lengauer, C., Nowak, M.A., 2003a. Colon cancer initiation. Submitted for publication.
23. Michor F., Iwasa Y., Komarova N.L., Nowak M.A. Local regulation of homeostasis favors chromosomal instability. Curr. Biol. 13:2003;581-584.
24. Michor, F., Nowak, M.A., Frank, S.A., Iwasa, Y., 2003c. Stochastic elimination of cancer cells. Proc. R. Soc. London B, in press.
25. Mintz B. Clonal basis of mammalian differentiation. Symp. Soc. Exp. Biol. 25:1971;345-370.
26. Mintz B. Malignancy vs. normal differentiation of stem cells as analyzed in genetically mosaic animals. Adv. Pathobiol. 6:1977;153-157.
27. Moolgavkar S.H., Knudson A.G. Mutation and cancer. a model for human carcinogenesis J. Natl Cancer Inst. 66:1981;1037-1052.
28. Nowak M.A., Komarova N.L., Sengupta A., Jallepalli P.F., Shih I.M., Vogelstein B., Lengauer C. The role of chromosomal instability in tumor initiation. Proc. Natl Acad. Sci. USA. 99:2002;16226-16231.
29. Sen S. Aneuploidy and cancer. Curr. Opin. Oncol. 12:2000;82-88.
30. Stehelin D., Varmus H.E., Bishop J.M., Vogt P.K. DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature. 260:1976;170-173.
31. Tomlinson I.P.M., Bodmer W. Selection, the mutation rate and cancer. ensuring that the tail does not wag the dog Nat. Med. 5:1999;11-12.
32. Tomlinson I.P.M., Novelli M.R., Bodmer W.F. The mutation rate and cancer. Proc. Natl Acad. Sci. USA. 93:1996;14800-14803.
33. Yatabe Y., Tavare S., Shibata D. Investigating stem cells in human colon by using methylation patterns. Proc. Natl Acad. Sci. USA. 98:2001;10839-10844.