Bcl-2 antisense in the treatment of human malignancies: A delusion in targeted therapy

Current Pharmaceutical Biotechnology

Volumn 8, Issue 6, 2007, Pages 373-381

  Gjertsen, Bjørn Tore ^a,b   Bredholt, Therese ^a   Ånensen, Nina ^a   Vintermyr, Olav Karsten ^c  

^a UNIVERSITY OF BERGEN   (Norway)

^b HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^c HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

Leukemia; Malignancy; Oligodeoxynucleotides; Phosphorothioate Oligonucleotide; RNAase

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; ALBUMIN; ANTISENSE OLIGODEOXYNUCLEOTIDE; BORTEZOMIB; CARBOPLATIN; CD20 ANTIBODY; CYCLOPHOSPHAMIDE; CYTARABINE; DACARBAZINE; DAUNORUBICIN; DEXAMETHASONE; DOCETAXEL; DOXORUBICIN; ETOPOSIDE; FLUDARABINE; GEMTUZUMAB OZOGAMICIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IRINOTECAN; LIPOPLEX; LIPOSOME; MESSENGER RNA; MITOXANTRONE; MYC PROTEIN; OBLIMERSEN; PACLITAXEL; POLYLYSINE; PROTEIN BCL 2; THALIDOMIDE; UNINDEXED DRUG; VINCRISTINE;

ACUTE GRANULOCYTIC LEUKEMIA; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; ASTHENIA; CARCINOGENESIS; CELL DEATH; CHROMOSOME TRANSLOCATION; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL TRIAL; DRUG DESIGN; DRUG TARGETING; FEVER; GENE OVEREXPRESSION; HEART DISEASE; HODGKIN DISEASE; HUMAN; HYPOTENSION; IMMUNE SYSTEM; KIDNEY DISEASE; MALIGNANT NEOPLASTIC DISEASE; NONHODGKIN LYMPHOMA; PARTIAL THROMBOPLASTIN TIME; PREDICTION; PROTEIN FAMILY; PROTEIN INTERACTION; REVIEW; RNA DEGRADATION; SIDE EFFECT; SIGNAL TRANSDUCTION; THROMBOCYTOPENIA; UPREGULATION;

ANTINEOPLASTIC AGENTS; CLINICAL TRIALS AS TOPIC; DRUG RESISTANCE, NEOPLASM; HUMANS; NEOPLASMS; OLIGONUCLEOTIDES, ANTISENSE; PROTO-ONCOGENE PROTEINS C-BCL-2; THIONUCLEOTIDES;

EID: 37249074364     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920107783018381     Document Type: Review

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