Changes in gene expression induced by phosphorothioate oligodeoxymeleotides (including G3139) in PC3 prostate carcinoma cells are recapitulated at least in part by treatment with interferon-β and -γ

Clinical Cancer Research

Volumn 10, Issue 11, 2004, Pages 3678-3688

  Benimetskaya, Luba ^a   Wittenberger, Timo ^c   Stein, C A ^a,e   Hofmann, Hans Peter ^c   Weller, Claudia ^c   Lai, Johnathan C ^a,b   Miller, Paul ^d   Gekeler, Volker ^c  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b Altana Pharma AG ^*  (United States)

^c ALTANA PHARMA AG   (Germany)

^d JOHNS HOPKINS UNIVERSITY   (United States)

^e ALBERT EINSTEIN CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CYCLIN DEPENDENT KINASE INHIBITOR 1; GAMMA INTERFERON; LIPOFECTIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; OBLIMERSEN; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; OLIGOMER; OLIGONUCLEOTIDE; PROTEIN; PROTEIN BCL 2; PROTEIN KINASE C ALPHA; PROTEIN P21; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL GROWTH; CLUSTER ANALYSIS; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; DRUG MECHANISM; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE INDUCTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR BIOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROSTATE CARCINOMA; PROTEIN EXPRESSION; PROTO ONCOGENE; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; UPREGULATION;

ALGORITHMS; ANNEXIN A5; ANTIBODIES, MONOCLONAL; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CLUSTER ANALYSIS; CPG ISLANDS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE THERAPY; HUMANS; INTERFERON TYPE II; INTERFERON-BETA; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OLIGONUCLEOTIDES; PHENOTYPE; PROSTATIC NEOPLASMS; PROTEIN ISOFORMS; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TRANSFECTION; UP-REGULATION;

EID: 2542576435     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-03-0569     Document Type: Article

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