Inhibition of GSK-3β mediates expression of MMP-9 through ERK1/2 activation and translocation of NF-κB in rat primary astrocyte

Brain Research

Volumn 1186, Issue 1, 2007, Pages 12-20

  Kim, Sun Don ^a   Yang, Sung Il ^b   Kim, Hyoung Chun ^c   Shin, Chan Young ^b   Ko, Kwang Ho ^a  

^a Seoul National University   (South Korea)

^b Konkuk University School of Medicine   (South Korea)

^c Kangwon National University   (South Korea)

Author keywords

ERK1 2; GSK 3 ; MMP 9; NF B; Primary cultured astrocyte

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ENZYME INHIBITOR; GELATINASE B; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; 4 BENZYL 2 METHYL 1,2,4 THIADIAZOLIDINE 3,5 DIONE; 4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE; GELATINASE A; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MESSENGER RNA; THIADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEOMICS; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CELL NUCLEUS; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN TRANSPORT; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ASTROCYTES; CELL NUCLEUS; CELLS, CULTURED; ENZYME INHIBITORS; GLYCOGEN SYNTHASE KINASE 3; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; PHOSPHORYLATION; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SIGNAL TRANSDUCTION; THIADIAZOLES;

EID: 36749071696     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.10.018     Document Type: Article

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