Curcumin suppresses phorbol ester-induced matrix metalloproteinase-9 expression by inhibiting the PKC to MAPK signaling pathways in human astroglioma cells

Biochemical and Biophysical Research Communications

Volumn 335, Issue 4, 2005, Pages 1017-1025

  Woo, Moon Sook ^a   Jung, Soo Hyun ^a   Kim, So Young ^a   Hyun, Jin Won ^b   Ko, Kwang Ho ^c   Kim, Won Ki ^a   Kim, Hee Sun ^a  

^a Ewha Womans University School of Medicine   (South Korea)

^b Jeju National University School of Medicine   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

AP 1; Astroglioma; Curcumin; Gene expression; MAP kinase; Matrix metalloproteinase 9; NF B; PKC; Signal transduction

Indexed keywords

CURCUMIN; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL ESTER; PROTEIN KINASE C; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

ARTICLE; ASTROCYTOMA CELL; CORRELATION ANALYSIS; DNA BINDING; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; ASTROCYTOMA; CELL LINE, TUMOR; CURCUMIN; DRUG INTERACTIONS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; PHORBOL ESTERS; PROTEIN KINASE C; SIGNAL TRANSDUCTION;

EID: 24044532589     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.07.174     Document Type: Article

References (27)

1. L.K. Phuong, C. Allen, K.W. Peng, C. Giannini, S. Greiner, C.J. TenEyck, P.K. Mishra, S.I. Macura, S.J. Russell, and E.C. Galanis Use of a vaccine strain of measles virus genetically engineered to produce carcinoembryonic antigen as a novel therapeutic agent against glioblastoma multiforme Cancer Res. 63 2003 2462 2469
2. H.I. Ma, S.Z. Lin, Y.H. Chiang, J. Li, S.L. Chen, Y.P. Tsao, and X. Xiao Intratumoral gene therapy of malignant brain tumor in a rat model with angiostatin delivered by adeno-associated viral (AAV) vector Gene Ther. 9 2002 2 11
3. A.R. Nelson, B. Fingleton, M.L. Rothenberg, and L.M. Matrisian Matrix metalloproteinases: biologic activity and clinical implications J. Clin. Oncol. 18 2000 1135 1149
4. T.H. Vu, and Z. Werb Matrix metalloproteinases: effectors of development and normal physiology Genes Dev. 14 2000 2123 2133
5. J.S. Rao, P.A. Steck, S. Mohanam, W.G. Stetler-Stevenson, L.A. Liotta, and R. Sawaya Elevated levels of M(r) 92,000 type IV collagenase in human brain tumors Cancer Res. 53 1993 2208 2211
6. S. Zucker, R.M. Lysik, M.H. Zarrabi, and U. Moll M(r) 92,000 type IV collagenase is increased in plasma of patients with colon cancer and breast cancer Cancer Res. 53 1993 140 146
7. G. Bergers, R. Brekken, G. McMahon, T.H. Vu, T. Itoh, K. Tamaki, K. Tanzawa, P. Thorpe, S. Itohara, Z. Werb, and D. Hanahan Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis Nat. Cell Biol. 2 2000 737 744
8. S. Chakraborti, M. Mandal, S. Das, A. Mandal, and T. Chakraborti Regulation of matrix metalloproteinases: an overview Mol. Cell. Biochem. 253 2003 269 285
9. B.B. Aggarwal, A. Kumar, and A.C. Bharti Anticancer potential of curcumin: preclinical and clinical studies Anticancer Res. 23 2003 363 398
10. J.H. Kim, J.S. Shim, S.K. Lee, K.W. Kim, S.Y. Rha, H.C. Chung, and H.J. Kwon Microarray-based analysis of anti-angiogenic activity of demethoxycurcumin on human umbilical vein endothelial cells: crucial involvement of the down-regulation of matrix metalloproteinase Jpn. J. Cancer Res. 93 2002 1378 1385
11. S. Shishodia, P. Potdar, C.G. Gairola, and B.B. Aggarwal Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1 Carcinogenesis 24 2003 1269 1279
12. L.I. Lin, Y.F. Ke, Y.C. Ko, and J.K. Lin Curcumin inhibits SK-Hep-1 hepatocellular carcinoma cell invasion in vitro and suppresses matrix metalloproteinase-9 secretion Oncology 55 1998 349 353
13. H.S. Kim, N.M. Goncalves, and J.W. Henson Glial cell-specific regulation of the JC virus early promoter by large T antigen J. Virol. 74 2000 755 763
14. Z. Ma, H. Qin, and E.N. Benveniste Transcriptional suppression of matrix metalloproteinase-9 gene expression by IFN-γ and IFN-β: critical role of STAT-1α J. Immunol. 167 2001 5150 5159
15. M.S. Woo, P.G. Jang, J.S. Park, W.K. Kim, T.H. Joh, and H.S. Kim Selective modulation of lipopolysaccharide-stimulated cytokine expression and mitogen-activated protein kinase pathways by dibutyryl-cAMP in BV2 microglial cells Mol. Brain. Res. 113 2003 86 96
16. R. Sawaya, Y. Go, A.P. Kyritisis, J. Uhm, B. Venkaiah, S. Mohanam, Z.L. Gokaslan, and J.S. Rao Elevated levels of Mr 92,000 type IV collagenase during tumor growth in vivo Biochem. Biophys. Res. Commun. 251 1998 632 636
17. S.S. Ambegaokar, L. Wu, K. Alamshahi, J. Lau, L. Jazayeri, S. Chan, P. Khanna, E. Hsieh, and P.S. Timiras Curcumin inhibits dose-dependently and time-dependently neuroglial cell proliferation and growth Neuro. Endocrinol. Lett. 24 2003 469 473
18. K. Kato, H. Ito, K. Kamei, and I. Iwamoto Stimulation of the stress-induced expression of stress proteins by curcumin in cultured cells and in rat tissues in vivo Cell Stress Chaperone 3 1998 152 160
19. S. Singh, and B.B. Aggarwal Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) J. Biol. Chem. 270 1995 24995 25000
20. C. Jobin, C.A. Bradham, M.P. Russo, B. Juma, A.S. Narula, D.A. Brenner, and R.B. Sartor Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity J. Immuonol. 163 1999 3474 3483
21. J.Y. Liu, S.J. Lin, and J.K. Lin Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoyl-phorbol-13-acetate in NIH 3T3 cells Carcinogenesis 14 1993 857 861
22. H.W. Chen, and H.C. Huang Effect of curcumin on cell cycle progression and apoptosis in vascular smooth muscle cells Br. J. Pharmacol. 124 1998 1029 1040
23. C. Simon, H. Goepfert, and D. Boyd Inhibition of the p38 mitogen-activated protein kinase by SB203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion Cancer Res. 58 1998 1135 1139
24. E. Genersch, K. Hayess, Y. Neuenfeld, and H. Haller Sustained ERK phosphorylation is necessary but not sufficient for MMP-9 regulation in endothelial cells: involvement of Ras-dependent and -independent pathways J. Cell Sci. 113 2000 4319 4330
25. R. Mohan, J. Sivak, P. Ashton, L.A. Russo, B.Q. Pham, N. Kasahara, M.B. Raizman, and M.E. Fini Curcuminoids inhibit the angiogenic response stimulated by fibroblast growth factor-2, including expression of matrix metalloproteinase gelatinase B J. Biol. Chem. 275 2000 10405 10412
26. G.P. Lim, T. Chu, F. Yang, W. Beech, S.A. Frautschy, and G.M. Cole The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse J. Neurosi. 21 2001 8370 8377
27. M. Thiyagarajan, and S.S. Sharma Neuroprotective effect of curcumin in middle cerebral artery occlusion induced focal cerebral ischemia in rats Life Sci. 74 2004 969 985