-
1
-
-
0032904641
-
Toxicity of hepatotoxins: New insights into mechanisms and therapy
-
Wu J, Danielsson A, Zern MA. Toxicity of hepatotoxins: New insights into mechanisms and therapy. Expert Opin Investig Drugs 1999; 8: 585-607.
-
(1999)
Expert Opin Investig Drugs
, vol.8
, pp. 585-607
-
-
Wu, J.1
Danielsson, A.2
Zern, M.A.3
-
2
-
-
33644895961
-
Molecular therapy for hepatic injury and fibrosis: Where are we?
-
Prosser CC, Yen RD, Wu J. Molecular therapy for hepatic injury and fibrosis: Where are we? World J Gastroenterol 2006; 12: 509-15.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 509-515
-
-
Prosser, C.C.1
Yen, R.D.2
Wu, J.3
-
4
-
-
16544383147
-
Alcohol, oxidative stress, and free radical damage
-
Wu D, Cederbaum AI. Alcohol, oxidative stress, and free radical damage. Alcohol Res Health 2003; 27: 277-84.
-
(2003)
Alcohol Res Health
, vol.27
, pp. 277-284
-
-
Wu, D.1
Cederbaum, A.I.2
-
5
-
-
0030860079
-
GSH transport in mitochondria: Defense against TNF-induced oxidative stress and alcohol-induced defect
-
Fernandez-Checa JC, Kaplowitz N, Garcia-Ruiz C, et al. GSH transport in mitochondria: Defense against TNF-induced oxidative stress and alcohol-induced defect. Am J Physiol 1997; 273: G7-17.
-
(1997)
Am J Physiol
, vol.273
-
-
Fernandez-Checa, J.C.1
Kaplowitz, N.2
Garcia-Ruiz, C.3
-
6
-
-
0037371816
-
Oxidants and antioxidants in alcohol-induced liver disease
-
Arteel GE. Oxidants and antioxidants in alcohol-induced liver disease. Gastroenterology 2003; 124: 778-90.
-
(2003)
Gastroenterology
, vol.124
, pp. 778-790
-
-
Arteel, G.E.1
-
7
-
-
0033057124
-
Acetaldehyde-mediated collagen regulation in hepatic stellate cells
-
Greenwel P. Acetaldehyde-mediated collagen regulation in hepatic stellate cells. Alcohol Clin Exp Res 1999; 23: 930-3.
-
(1999)
Alcohol Clin Exp Res
, vol.23
, pp. 930-933
-
-
Greenwel, P.1
-
8
-
-
33645243410
-
Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo
-
Zhan SS, Jiang JX, Wu J, et al. Phagocytosis of apoptotic bodies by hepatic stellate cells induces NADPH oxidase and is associated with liver fibrosis in vivo. Hepatology 2006; 43: 435-43.
-
(2006)
Hepatology
, vol.43
, pp. 435-443
-
-
Zhan, S.S.1
Jiang, J.X.2
Wu, J.3
-
9
-
-
33845336554
-
Randomized placebo-controlled trial of ursodeoxycholic acid with vitamin E in nonalcoholic steatohepatitis
-
Dufour JF, Oneta CM, Gonvers JJ, et al. Randomized placebo-controlled trial of ursodeoxycholic acid with vitamin E in nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol 2006; 4: 1537-43.
-
(2006)
Clin Gastroenterol Hepatol
, vol.4
, pp. 1537-1543
-
-
Dufour, J.F.1
Oneta, C.M.2
Gonvers, J.J.3
-
10
-
-
24944489381
-
Vasoconstrictor hyporeactivity can be reversed by antioxidants in patients with advanced alcoholic cirrhosis of the liver and ascites
-
Ferlitsch A, Pleiner J, Mittermayer F, et al. Vasoconstrictor hyporeactivity can be reversed by antioxidants in patients with advanced alcoholic cirrhosis of the liver and ascites. Crit Care Med 2005; 33: 2028-33.
-
(2005)
Crit Care Med
, vol.33
, pp. 2028-2033
-
-
Ferlitsch, A.1
Pleiner, J.2
Mittermayer, F.3
-
12
-
-
0036257518
-
Oxidative stress, plant-derived antioxidants and liver fibrosis
-
Gebhardt R. Oxidative stress, plant-derived antioxidants and liver fibrosis. Planta Med 2002; 68: 289-96.
-
(2002)
Planta Med
, vol.68
, pp. 289-296
-
-
Gebhardt, R.1
-
13
-
-
0034859659
-
Silymarin: A review of its clinical properties in the management of hepatic disorders
-
Wellington K, Jarvis B. Silymarin: A review of its clinical properties in the management of hepatic disorders. BioDrugs 2001; 15: 465-89.
-
(2001)
BioDrugs
, vol.15
, pp. 465-489
-
-
Wellington, K.1
Jarvis, B.2
-
14
-
-
0035062753
-
Invited review: Manganese superoxide dismutase in disease
-
Macmillan-Crow LA, Cruthirds DL. Invited review: Manganese superoxide dismutase in disease. Free Radic Res 2001; 34: 325-36.
-
(2001)
Free Radic Res
, vol.34
, pp. 325-336
-
-
Macmillan-Crow, L.A.1
Cruthirds, D.L.2
-
15
-
-
0036121283
-
Extracellular superoxide dismutase
-
Marklund SL. Extracellular superoxide dismutase. Methods Enzymol 2002; 349: 74-80.
-
(2002)
Methods Enzymol
, vol.349
, pp. 74-80
-
-
Marklund, S.L.1
-
16
-
-
0035078936
-
Delivery of the Cu/Zn-superoxide dismutase gene with adenovirus reduces early alcohol-induced liver injury in rats
-
Wheeler MD, Kono H, Yin M, et al. Delivery of the Cu/Zn-superoxide dismutase gene with adenovirus reduces early alcohol-induced liver injury in rats. Gastroenterology 2001; 120: 1241-50.
-
(2001)
Gastroenterology
, vol.120
, pp. 1241-1250
-
-
Wheeler, M.D.1
Kono, H.2
Yin, M.3
-
17
-
-
0142151776
-
Adenovirus-mediated expression of Cu/Zn- or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity
-
Perez MJ, Cederbaum AI. Adenovirus-mediated expression of Cu/Zn- or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity. Hepatology 2003; 38: 1146-58.
-
(2003)
Hepatology
, vol.38
, pp. 1146-1158
-
-
Perez, M.J.1
Cederbaum, A.I.2
-
18
-
-
3042697876
-
Liposome-mediated extracellular superoxide dismutase gene delivery protects against acute liver injury in mice
-
Wu J, Liu L, Yen RD, et al. Liposome-mediated extracellular superoxide dismutase gene delivery protects against acute liver injury in mice. Hepatology 2004; 40: 195-204.
-
(2004)
Hepatology
, vol.40
, pp. 195-204
-
-
Wu, J.1
Liu, L.2
Yen, R.D.3
-
19
-
-
33845472283
-
Delivery of antioxidative enzyme genes protects against ischemia/ reperfusion-induced liver injury in mice
-
He SQ, Zhang YH, Venugopal SK, et al. Delivery of antioxidative enzyme genes protects against ischemia/reperfusion-induced liver injury in mice. Liver Transplant 2006; 12: 1869-79.
-
(2006)
Liver Transplant
, vol.12
, pp. 1869-1879
-
-
He, S.Q.1
Zhang, Y.H.2
Venugopal, S.K.3
-
20
-
-
0036370361
-
Generation of HIV-1 derived lentiviral vectors
-
Follenzi A, Naldini L. Generation of HIV-1 derived lentiviral vectors. Methods Enzymol 2002; 346: 454-65.
-
(2002)
Methods Enzymol
, vol.346
, pp. 454-465
-
-
Follenzi, A.1
Naldini, L.2
-
21
-
-
0036171327
-
Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors
-
Follenzi A, Sabatino G, Lombardo A, et al. Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors. Hum Gene Ther 2002; 13: 243-60.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 243-260
-
-
Follenzi, A.1
Sabatino, G.2
Lombardo, A.3
-
22
-
-
0036682975
-
Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo
-
VandenDriessche T, Thorrez L, Naldini L, et al. Lentiviral vectors containing the human immunodeficiency virus type-1 central polypurine tract can efficiently transduce nondividing hepatocytes and antigen-presenting cells in vivo. Blood 2002; 100: 813-22.
-
(2002)
Blood
, vol.100
, pp. 813-822
-
-
VandenDriessche, T.1
Thorrez, L.2
Naldini, L.3
-
23
-
-
0034989411
-
Transduction of liver cells by lentiviral vectors: Analysis in living animals by fluorescence imaging
-
Pfeifer A, Kessler T, Yang M, et al. Transduction of liver cells by lentiviral vectors: Analysis in living animals by fluorescence imaging. Mol Ther 2001; 3: 319-22.
-
(2001)
Mol Ther
, vol.3
, pp. 319-322
-
-
Pfeifer, A.1
Kessler, T.2
Yang, M.3
-
24
-
-
0038036669
-
Repopulation of rat liver by fetal hepatoblasts and adult hepatocytes transduced ex vivo with lentiviral vectors
-
Oertel M, Rosencrantz R, Chen YQ, et al. Repopulation of rat liver by fetal hepatoblasts and adult hepatocytes transduced ex vivo with lentiviral vectors. Hepatology 2003; 37: 994-1005.
-
(2003)
Hepatology
, vol.37
, pp. 994-1005
-
-
Oertel, M.1
Rosencrantz, R.2
Chen, Y.Q.3
-
25
-
-
0036664451
-
Highly efficient lentiviral vector-mediated transduction of nondividing, fully reimplantable primary hepatocytes
-
Nguyen TH, Oberholzer J, Birraux J, et al. Highly efficient lentiviral vector-mediated transduction of nondividing, fully reimplantable primary hepatocytes. Mol Ther 2002; 6: 199-209.
-
(2002)
Mol Ther
, vol.6
, pp. 199-209
-
-
Nguyen, T.H.1
Oberholzer, J.2
Birraux, J.3
-
26
-
-
2342561729
-
Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice
-
Follenzi A, Battaglia M, Lombardo A, et al. Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice. Blood 2004; 103: 3700-9.
-
(2004)
Blood
, vol.103
, pp. 3700-3709
-
-
Follenzi, A.1
Battaglia, M.2
Lombardo, A.3
-
27
-
-
3042717155
-
Prolonged liver-specific transgene expression by a non-primate lentiviral vector
-
Condiotti R, Curran MA, Nolan GP, et al. Prolonged liver-specific transgene expression by a non-primate lentiviral vector. Biochem Biophys Res Commun 2004; 320: 998-1006.
-
(2004)
Biochem Biophys Res Commun
, vol.320
, pp. 998-1006
-
-
Condiotti, R.1
Curran, M.A.2
Nolan, G.P.3
-
28
-
-
0035988776
-
HIV-based vectors. Preparation and use
-
Follenzi A, Naldini L. HIV-based vectors. Preparation and use. Methods Mol Med 2002; 69: 259-74.
-
(2002)
Methods Mol Med
, vol.69
, pp. 259-274
-
-
Follenzi, A.1
Naldini, L.2
-
29
-
-
0028847434
-
Vitamin E therapy of acute CCl4-induced hepatic injury in mice is associated with inhibition of nuclear factor kappa B binding
-
Liu SL, Degli Esposti S, Yao T, et al. Vitamin E therapy of acute CCl4-induced hepatic injury in mice is associated with inhibition of nuclear factor kappa B binding. Hepatology 1995; 22: 1474-81.
-
(1995)
Hepatology
, vol.22
, pp. 1474-1481
-
-
Liu, S.L.1
Degli Esposti, S.2
Yao, T.3
-
30
-
-
12144255424
-
Hyperglycemia induces monocytic release of interleukin-6 via induction of protein kinase c-{alpha} and -{beta}
-
Devaraj S, Venugopal SK, Singh U, Jialal I. Hyperglycemia induces monocytic releaseof interleukin-6 via induction of protein kinase c-{alpha} and -{beta}. Diabetes 2005; 54: 85-91.
-
(2005)
Diabetes
, vol.54
, pp. 85-91
-
-
Devaraj, S.1
Venugopal, S.K.2
Singh, U.3
Jialal, I.4
-
31
-
-
2442534076
-
Differentiation of human and mouse embryonic stem cells along a hepatocyte lineage
-
Shirahashi H, Wu J, Yamamoto N, et al. Differentiation of human and mouse embryonic stem cells along a hepatocyte lineage. Cell Transplant 2004; 13: 197-211.
-
(2004)
Cell Transplant
, vol.13
, pp. 197-211
-
-
Shirahashi, H.1
Wu, J.2
Yamamoto, N.3
-
32
-
-
25144463539
-
The contemporary role of antioxidant therapy in attenuating liver ischemia-reperfusion injury: A review
-
Glantzounis GK, Salacinski HJ, Yang W, et al. The contemporary role of antioxidant therapy in attenuating liver ischemia-reperfusion injury: A review. Liver Transplant 2005; 11: 1031-47.
-
(2005)
Liver Transplant
, vol.11
, pp. 1031-1047
-
-
Glantzounis, G.K.1
Salacinski, H.J.2
Yang, W.3
-
33
-
-
0037962331
-
Effects of three superoxide dismutase genes delivered with an adenovirus on graft function after transplantation of fatty livers in the rat
-
Lehmann TG, Wheeler MD, Froh M, et al. Effects of three superoxide dismutase genes delivered with an adenovirus on graft function after transplantation of fatty livers in the rat. Transplantation 2003; 76: 28-37.
-
(2003)
Transplantation
, vol.76
, pp. 28-37
-
-
Lehmann, T.G.1
Wheeler, M.D.2
Froh, M.3
-
34
-
-
0035685562
-
Comparison of the effect of adenoviral delivery of three superoxide dismutase genes against hepatic ischemia-reperfusion injury
-
Wheeler MD, Katuna M, Smutney OM, et al. Comparison of the effect of adenoviral delivery of three superoxide dismutase genes against hepatic ischemia-reperfusion injury. Hum Gene Ther 2001; 12: 2167-77.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 2167-2177
-
-
Wheeler, M.D.1
Katuna, M.2
Smutney, O.M.3
-
35
-
-
16544373246
-
Dangerous byproducts of alcohol breakdown - Focus on adducts
-
Tuma DJ, Casey CA. Dangerous byproducts of alcohol breakdown - focus on adducts. Alcohol Res Health 2003; 27: 285-90.
-
(2003)
Alcohol Res Health
, vol.27
, pp. 285-290
-
-
Tuma, D.J.1
Casey, C.A.2
-
36
-
-
0037385083
-
Amelioration of antigen-induced arthritis in rats by transfer of extracellular superoxide dismutase and catalase genes
-
Dai L, Claxson A, Marklund SL, et al. Amelioration of antigen-induced arthritis in rats by transfer of extracellular superoxide dismutase and catalase genes. Gene Ther 2003; 10: 550-8.
-
(2003)
Gene Ther
, vol.10
, pp. 550-558
-
-
Dai, L.1
Claxson, A.2
Marklund, S.L.3
-
37
-
-
0031923328
-
Cytotoxic T-lymphocyte target proteins and their major histocompatibility complex class I restriction in response to adenovirus vectors delivered to mouse liver
-
Jooss K, Ertl HC, Wilson JM. Cytotoxic T-lymphocyte target proteins and their major histocompatibility complex class I restriction in response to adenovirus vectors delivered to mouse liver. J Virol 1998; 72: 2945-54.
-
(1998)
J Virol
, vol.72
, pp. 2945-2954
-
-
Jooss, K.1
Ertl, H.C.2
Wilson, J.M.3
-
38
-
-
0036376642
-
Influence of vector dose on factor IX-specific T and B cell responses in muscle-directed gene therapy
-
Herzog RW, Fields PA, Arruda VR, et al. Influence of vector dose on factor IX-specific T and B cell responses in muscle-directed gene therapy. Hum Gene Ther 2002; 13: 1281-91.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1281-1291
-
-
Herzog, R.W.1
Fields, P.A.2
Arruda, V.R.3
-
39
-
-
0034986416
-
Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages
-
Zhang Y, Chirmule N, Gao GP, et al. Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages. Mol Ther 2001; 3: 697-707.
-
(2001)
Mol Ther
, vol.3
, pp. 697-707
-
-
Zhang, Y.1
Chirmule, N.2
Gao, G.P.3
-
40
-
-
0031034030
-
Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration
-
Worgall S, Wolff G, Falck-Pedersen E, Crystal RG. Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration. Hum Gene Ther 1997; 8: 37-44.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 37-44
-
-
Worgall, S.1
Wolff, G.2
Falck-Pedersen, E.3
Crystal, R.G.4
-
42
-
-
5444237545
-
Liver gene therapy: Advances and hurdles
-
Nguyen TH, Ferry N. Liver gene therapy: Advances and hurdles. Gene Ther 2004; 11 (Suppl. 1): S76-84.
-
(2004)
Gene Ther
, vol.11
, Issue.SUPPL. 1
-
-
Nguyen, T.H.1
Ferry, N.2
-
43
-
-
0037448352
-
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina S, von Kalle C, Schmidt M, et al. A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N Engl J Med 2003; 348: 255-6.
-
(2003)
N Engl J Med
, vol.348
, pp. 255-256
-
-
Hacein-Bey-Abina, S.1
von Kalle, C.2
Schmidt, M.3
-
44
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
Hacein-Bey-Abina S, Von Kalle C, Schmidt M, et al. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 2003; 302: 415-9.
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
-
45
-
-
1642381836
-
Direct exposure of mouse spermatozoa to very high concentrations of a serotype-2 adeno-associated virus gene therapy vector fails to lead to germ cell transduction
-
Couto L, Parker A, Gordon JW. Direct exposure of mouse spermatozoa to very high concentrations of a serotype-2 adeno-associated virus gene therapy vector fails to lead to germ cell transduction. Hum Gene Ther 2004; 15: 287-91.
-
(2004)
Hum Gene Ther
, vol.15
, pp. 287-291
-
-
Couto, L.1
Parker, A.2
Gordon, J.W.3
-
46
-
-
7244233034
-
Patterns of transgene expression and viral clearance from the transplanted liver following ex vivo adenovirus-mediated gene transfer
-
Zamir G, Gelman AE, Olthoff KM, et al. Patterns of transgene expression and viral clearance from the transplanted liver following ex vivo adenovirus-mediated gene transfer. J Hepatol 2004; 41: 714-20.
-
(2004)
J Hepatol
, vol.41
, pp. 714-720
-
-
Zamir, G.1
Gelman, A.E.2
Olthoff, K.M.3
-
47
-
-
36349011142
-
Differentiation and enrichment of hepatocyte-like cells from human embryonic stem cells using a liver-specific lentivirus vector and laser microdissection
-
Duan Y, Catana A, Gupta S, Zern MA. Differentiation and enrichment of hepatocyte-like cells from human embryonic stem cells using a liver-specific lentivirus vector and laser microdissection. Hepatology 2006; 44: 204A.
-
(2006)
Hepatology
, vol.44
-
-
Duan, Y.1
Catana, A.2
Gupta, S.3
Zern, M.A.4
|