Cytotoxic T-lymphocyte target proteins and their major histocompatibility complex class I restriction in response to adenovirus vectors delivered to mouse liver

Journal of Virology

Volumn 72, Issue 4, 1998, Pages 2945-2954

  Jooss, Karin ^a   Ertl, Hildegund C J ^a   Wilson, James M ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BETA GALACTOSIDASE; CELL PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; VIRUS VECTOR;

ADENOVIRUS; ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CYTOTOXIC T LYMPHOCYTE; GENE EXPRESSION; GENETIC HETEROGENEITY; HAPLOTYPE; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; VACCINIA VIRUS;

EID: 0031923328     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.4.2945-2954.1998     Document Type: Article

References (38)

1. Bennink, J. R., J. W. Yewdell, G. L. Smith, C. Moller, and B. Moss. 1990. Recombinant vaccinia virus primes and stimulates influenza haemagglutinin-specific cytotoxic T cells. Nature 311:578-579.
2. Bennink, J. R., J. W. Yewdell, G. L. Smith, and B. Moss. 1987. Anti-influenza virus cytotoxic T lymphocytes recognize the three viral polymerases and a nonstructural protein: responsiveness to individual viral antigens is major histocompatibility complex controlled. J. Virol. 61:1098-1102.
3. Brough, D. E., V. Cleghon, and D. F. Klessig. 1992. Construction, characterization, and utilization of cell lines which inducibly express the adenovirus DNA-binding protein. Virology 190:624-634.
4. Chakrabarti, S., K. Brechling, and B. Moss. 1985. Vaccinia virus vector: coexpression of β-galactosidase provides visual screening of recombinant virus plaques. Mol. Cell. Biol. 5:3403-3409.
5. Chroboczek, J., and B. Jacrot. 1987. The sequence of adenovirus fiber: similarities and differences between serotypes 2 and 5. Virology 161:549-554.
6. Davidson, B. L., E. D. Allen, K. F. Kozarsky, J. M. Wilson, and B. J. Roessler. 1993. A model system for in vivo gene transfer into the central nervous system using an adenoviral vector. Nat. Genet. 3:219-223.
7. Gmur R., D. Solter, and B. Knowles. 1980. Independent regulation of H-2K and H-2D gene expression in murine teratocarcinoma somatic cell hybrids. J. Exp. Med. 151:1349-1359.
8. Goldman, M. J., and J. M. Wilson. 1995. Transfer of the CFTR gene to the lung of nonhuman primates with E1 deleted, E2a defective recombinant adenoviruses: a preclinical toxicology study. Hum. Gene Ther. 6:839-851.
9. Horwitz, M. S. 1990. Adenoviridae and their replication, p. 1679-1721. In B. N. Fields, D. M. Knipe, et al. (ed.), Virology. Raven Press, New York, N.Y.
10. Imperiale, M. J., H.-T. Kao, L. T. Feldman, J. R. Nevins, and S. Strickland. 1984. Common control of the heat shock gene and early adenovirus genes: evidence for a cellular E1A-like activity. Mol. Cell. Biol. 4:867-874.
11. Kaplan, J. M., D. Armentano, T. E. Sparer, S. G. Wynn, P. A. Peterson, S. C. Wadsworth, K. K. Couture, P. A. Pennington, J. A. S. George, L. R. Gooding, and A. E. Smith. 1997. Characterization of factors involved in modulating persistence of transgene expression from recombinant adenovirus in the mouse lung. Hum. Gene Ther. 8:45-56.
12. Kinloch, R., N. Mackay, and V. Mautner. 1984. Adenovirus hexon. J. Biol. Chem. 259:6431-6436.
13. Knowles, B. B., M. Knocar, K. Pfitzenmaier, D. Solter, D. P. Aden, and G. Trinchierai. 1979. Genetic control of the cytotoxic T cell response to SV40 tumor-associated specific antigen. J. Immunol. 122:1798-1806.
14. Larson, J. K., W. H. Wunner, L. Otvos, and H. C. J. Ertl. 1991. Identification of an immunodominant epitope within the phosphoprotein of rabies virus that is recognized by both class I- and class II-restricted T cells. J. Virol. 65:5673-5679.
15. Muellbacher, A., A. J. D. Bellet, and R. T. Hla. 1989. The murine cellular immune response to adenovirus 5. Immunol. Cell Biol. 67:31-39.
16. Neumann, R., J. Chroboczek, and B. Jacrot. 1988. Determination of the nucleotide sequence for the penton-base gene of human adenovirus type 5. Gene 69:153-157.
17. Ragot, T., N. Vincent, P. Chafey, E. Vigne, H. Gilgenkrantz, D. Couton, J. Cartaud, P. Briand, J. Kaplan, and M. Perricaudet. 1993. Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice. Nature 361:647-650.
18. Rawle, F. C., B. B. Knowles, R. P. Ricciardi, V. Brahmacheri, P. Duerksen-Hughes, W. S. M. Wold, and L. R. Gooding. 1991. Specificity of the mouse cytotoxic T lymphocyte response to adenovirus 5. J. Immunol. 146:3977-3984.
19. Rosenfeld, M. A., W. Siegfried, K. Yoshimura, K. Yoneyama, M. Fukayama, L. E. Stier, P. K. Paakko, P. Gilardi, L. D. Stratford-Perricaudet, and M. Perricaudet. 1991. Adenovirus-mediated transfer of a recombinant α1-antitrypsin gene to the lung epithelium in vivo. Science 252:431-434.
20. Rosenfeld, M. A., K. Yoshimura, B. C. Trapnell, K. Yoneyama, E. R. Rosenthal, W. Dalemans, M. Fukayama, J. Bargon, L. E. Stier, and L. Stratford-Perricaudet. 1992. In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium. Cell 68:143-155.
21. Sasaguri, Y., T. Sanford, P. Aguirre, and R. Padmanabhan. 1987. Immunological analysis of 140-kDa adenovirus-encoded DNA polymerase in adenovirus type 2-infected Hela cells using antibodies raised against the protein expressed in escherichia coli. Virology 160:389-399.
22. Schreiber, J. H., J. A. Schisa, and J. M. Wilson. 1993. Recombinant retroviruses containing novel reporter genes. BioTechniques 14:818-823.
23. Sparer, T. E., S. G. Wynn, D. J. Clark, J. M. Kaplan, L. M. Cardoza, S. C. Wadsworth, A. E. Smith, and L. R. Gooding. 1997. Generation of cytotoxic T lymphocytes against immunorecessive epitopes after multiple immunizations with adenovirus vectors is dependent on haplotype. J. Virol. 71:2277-2284.
24. Spergel, J. M., W. Hsu, S. Akira, B. Thimmappaya, T. Kishimoto, and S. Chen-Kiang. 1992. NF-IL6, a member of the C/EBP family, regulates E1A-responsive promoters in the absence of E1A. J. Virol. 66:1021-1030.
25. Stratford-Perricaudet, L. D., I. Makeh, M. Perricaudet, and P. Briand. 1992. Widespread long-term gene transfer to mouse skeletal muscle and heart. J. Clin. Invest. 90:626-630.
26. Townsend, A., and H. Bodmer. 1989. Antigen recognition by class I-restricted T lymphocytes. Annu. Rev. Immunol. 7:601-624.
27. Townsend, A. R. M., J. Rothbard, F. M. Gotch, G. Bahadur, D. Wraith, and A. J. McMichael. 1986. The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell 44:959-968.
28. Tripathy, S. K., H. B. Black, E. Goldwasser, and J. M. Leiden. 1996. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors. Nat. Med. 2:545-550.
29. Whitton, J. L., P. J. Southern, and M. B. A. Oldstone. 1988. Analyses of the cytotoxic T lymphocyte responses to glycoprotein and nucleoprotein components of lymphocytic choriomeningitis virus. Virology 162:321-327.
30. Xiang, Z., S. Spitalnik, M. Tran, W. H. Wunner, J. Cheng, and H. C. J. Ertl. 1994. Vaccination with a plasmid vector carrying the rabies virus glycoprotein gene induces protective immunity against rabies virus. Virology 199: 132-140.
31. Yang, Y., H. C. J. Ertl, and J. M. Wilson. 1994. MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses. Immunity 1:433-442.
32. Yang, Y., K. U. Jooss, Q. Su, H. C. J. Ertl, and J. M. Wilson. 1996. Immune responses to viral antigens versus transgene product in the elimination of recombinant adenovirus-infected hepatocytes in vivo. Gene Ther. 3:137-144.
33. Yang, Y., Q. Li, H. C. J. Ertl, and J. M. Wilson. 1995. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenovirus. J. Virol. 69:2004-2015.
34. Yang, Y., F. A. Nunes, K. Berencsi, E. E. Furth, E. Gonczol, and J. M. Wilson. 1994. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc. Natl. Acad. Sci. USA 91:4407-4411.
35. Yang, Y., F. A. Nunes, K. Berencsi, E. Gonczol, J. F. Engelhardt, and J. M. Wilson. 1994. Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis. Nat. Genet. 7:362-369.
36. Yang, Y., Z. Xiang, H. C. J. Ertl, and J. M. Wilson. 1995. Upregulation of class I major histocompatibility complex antigens by Interferon γ is necessary for T-cell mediated elimination of recombinant adenovirus-infected hepatocytes in vivo. Proc. Natl. Acad. Sci. USA 92:7257-7261.
37. Yewdell, J., J. R. Bennink, M. Mackett, L. Lefrancois, D. S. Lyles, and B. Moss. 1986. Recognition of cloned vesicular stromatitis virus internal and external gene products by cytotoxic T lymphocytes. J. Exp. Med. 163:1529-1538.
38. Yewdell, J. W., J. R. Bennink, G. L. Smith, and B. Moss. 1985. Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. USA 82:1785-1789.