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Volumn 167, Issue , 2007, Pages 65-77

Mice that under- or overexpress glucocorticoid receptors as models for depression or posttraumatic stress disorder

Author keywords

behavior; glucocorticoid receptor; HPA system; learned helplessness; mice; stress

Indexed keywords

GLUCOCORTICOID RECEPTOR; IMIPRAMINE;

EID: 36248988437     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(07)67005-8     Document Type: Review
Times cited : (17)

References (50)
  • 1
    • 26844522889 scopus 로고    scopus 로고
    • Neural circuit changes mediating lasting brain and behavioral response to predator stress
    • Adamec R.E., Blundell J., and Burton P. Neural circuit changes mediating lasting brain and behavioral response to predator stress. Neurosci. Biobehav. Rev. 29 8 (2005) 225-1241
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , Issue.8 , pp. 225-1241
    • Adamec, R.E.1    Blundell, J.2    Burton, P.3
  • 2
    • 0035709356 scopus 로고    scopus 로고
    • Neural plasticity and stress induced changes in defense in the rat
    • Adamec R.E., Blundell J., and Collins A. Neural plasticity and stress induced changes in defense in the rat. Neurosci. Biobehav. Rev. 25 7-8 (2001) 721-744
    • (2001) Neurosci. Biobehav. Rev. , vol.25 , Issue.7-8 , pp. 721-744
    • Adamec, R.E.1    Blundell, J.2    Collins, A.3
  • 3
    • 0025754221 scopus 로고
    • Effect of age on the cortisol response to human corticotropin-releasing hormone in depressed patients pretreated with dexamethasone
    • von Bardeleben U., and Holsboer F. Effect of age on the cortisol response to human corticotropin-releasing hormone in depressed patients pretreated with dexamethasone. Biol. Psychiatry 29 10 (1991) 1042-1050
    • (1991) Biol. Psychiatry , vol.29 , Issue.10 , pp. 1042-1050
    • von Bardeleben, U.1    Holsboer, F.2
  • 4
    • 0030029963 scopus 로고    scopus 로고
    • Modulation of glucocorticoid receptor gene expression by antidepressant drugs
    • Barden N. Modulation of glucocorticoid receptor gene expression by antidepressant drugs. Pharmacopsychiatry 29 1 (1996) 12-22
    • (1996) Pharmacopsychiatry , vol.29 , Issue.1 , pp. 12-22
    • Barden, N.1
  • 5
    • 0030837391 scopus 로고    scopus 로고
    • Endocrine profile and neuroendocrine challenge tests in transgenic mice expressing antisense RNA against the glucocorticoid receptor
    • Barden N., Stec I.S., Montkowski A., Holsboer F., and Reul J.M. Endocrine profile and neuroendocrine challenge tests in transgenic mice expressing antisense RNA against the glucocorticoid receptor. Neuroendocrinology 66 3 (1997) 212-220
    • (1997) Neuroendocrinology , vol.66 , Issue.3 , pp. 212-220
    • Barden, N.1    Stec, I.S.2    Montkowski, A.3    Holsboer, F.4    Reul, J.M.5
  • 6
    • 0029618368 scopus 로고
    • Steroid hormone receptors: many actors in search of a plot
    • Beato M., Herrlich P., and Schütz G. Steroid hormone receptors: many actors in search of a plot. Cell 83 (1995) 851-857
    • (1995) Cell , vol.83 , pp. 851-857
    • Beato, M.1    Herrlich, P.2    Schütz, G.3
  • 7
    • 12244264438 scopus 로고    scopus 로고
    • Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior
    • Boyle M.P., Brewer J.A., Funatsu M., Wozniak D.F., Tsien J.Z., Izumi Y., et al. Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior. Proc. Natl. Acad. Sci. U.S.A. 102 2 (2005) 473-478
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , Issue.2 , pp. 473-478
    • Boyle, M.P.1    Brewer, J.A.2    Funatsu, M.3    Wozniak, D.F.4    Tsien, J.Z.5    Izumi, Y.6
  • 8
    • 33644506832 scopus 로고    scopus 로고
    • Forebrain glucocorticoid receptors modulate anxiety-associated locomotor activation and adrenal responsiveness
    • Boyle M.P., Kolber B.J., Vogt S.K., Wozniak D.F., and Muglia L.J. Forebrain glucocorticoid receptors modulate anxiety-associated locomotor activation and adrenal responsiveness. J. Neurosci. 26 7 (2006) 1971-1978
    • (2006) J. Neurosci. , vol.26 , Issue.7 , pp. 1971-1978
    • Boyle, M.P.1    Kolber, B.J.2    Vogt, S.K.3    Wozniak, D.F.4    Muglia, L.J.5
  • 10
    • 4143096768 scopus 로고    scopus 로고
    • CRH, stress, and major depression: a psychobiological interplay
    • Claes S.J. CRH, stress, and major depression: a psychobiological interplay. Vitam. Horm. 69 (2004) 117-150
    • (2004) Vitam. Horm. , vol.69 , pp. 117-150
    • Claes, S.J.1
  • 11
    • 0029088326 scopus 로고
    • Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation
    • Cole T.J., Blendy J.A., Monaghan A.P., Krieglstein K., Schmid W., Aguzzi A., et al. Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev. 9 13 (1995) 1608-1621
    • (1995) Genes Dev. , vol.9 , Issue.13 , pp. 1608-1621
    • Cole, T.J.1    Blendy, J.A.2    Monaghan, A.P.3    Krieglstein, K.4    Schmid, W.5    Aguzzi, A.6
  • 12
    • 0035931996 scopus 로고    scopus 로고
    • GRKO mice express an aberrant dexamethasone-binding glucocorticoid receptor, but are profoundly glucocorticoid resistant
    • Cole T.J., Myles K., Purton J.F., Brereton P.S., Solomon N.M., Godfrey D.I., et al. GRKO mice express an aberrant dexamethasone-binding glucocorticoid receptor, but are profoundly glucocorticoid resistant. Mol. Cell. Endocrinol. 173 1-2 (2001) 193-202
    • (2001) Mol. Cell. Endocrinol. , vol.173 , Issue.1-2 , pp. 193-202
    • Cole, T.J.1    Myles, K.2    Purton, J.F.3    Brereton, P.S.4    Solomon, N.M.5    Godfrey, D.I.6
  • 13
    • 2042546746 scopus 로고    scopus 로고
    • In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice
    • Cryan J.F., and Mombereau C. In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice. Mol. Psychiatry 9 4 (2004) 326-357
    • (2004) Mol. Psychiatry , vol.9 , Issue.4 , pp. 326-357
    • Cryan, J.F.1    Mombereau, C.2
  • 15
    • 0036752723 scopus 로고    scopus 로고
    • New insights into the role of cortisol and the glucocorticoid receptor in severe depression
    • Gold P.W., Drevets W.C., and Charney D.S. New insights into the role of cortisol and the glucocorticoid receptor in severe depression. Biol. Psychiatry 52 5 (2002) 381-385
    • (2002) Biol. Psychiatry , vol.52 , Issue.5 , pp. 381-385
    • Gold, P.W.1    Drevets, W.C.2    Charney, D.S.3
  • 16
    • 0029861030 scopus 로고    scopus 로고
    • Combined dexamethasone/CRH test in rats: hypothalamo-pituitary-adrenocortical system alterations in aging
    • Hatzinger M., Reul J.M.H.M., Landgraf R., Holsboer F., and Neumann I. Combined dexamethasone/CRH test in rats: hypothalamo-pituitary-adrenocortical system alterations in aging. Neuroendocrinology 64 (1996) 349-356
    • (1996) Neuroendocrinology , vol.64 , pp. 349-356
    • Hatzinger, M.1    Reul, J.M.H.M.2    Landgraf, R.3    Holsboer, F.4    Neumann, I.5
  • 17
    • 0027988726 scopus 로고
    • The combined dexamethasone/CRH test: a refined laboratory test for psychiatric disorders
    • Heuser I., Yassouridis A., and Holsboer F. The combined dexamethasone/CRH test: a refined laboratory test for psychiatric disorders. J. Psychiatr. Res. 28 4 (1994) 341-356
    • (1994) J. Psychiatr. Res. , vol.28 , Issue.4 , pp. 341-356
    • Heuser, I.1    Yassouridis, A.2    Holsboer, F.3
  • 18
    • 0033797445 scopus 로고    scopus 로고
    • The corticosteroid receptor hypothesis of depression
    • Holsboer F. The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology 23 5 (2000) 477-501
    • (2000) Neuropsychopharmacology , vol.23 , Issue.5 , pp. 477-501
    • Holsboer, F.1
  • 19
    • 0036698167 scopus 로고    scopus 로고
    • Stress in the brain: implications for treatment of depression
    • de Kloet E.R. Stress in the brain: implications for treatment of depression. Acta Neuropsychiatrica 14 (2002) 155-166
    • (2002) Acta Neuropsychiatrica , vol.14 , pp. 155-166
    • de Kloet, E.R.1
  • 20
    • 33846463782 scopus 로고    scopus 로고
    • Therapy insight: is there an imbalanced response of mineralocorticoid and glucocorticoid receptors in depression?
    • de Kloet E.R., Derijk R.H., and Meijer O.C. Therapy insight: is there an imbalanced response of mineralocorticoid and glucocorticoid receptors in depression?. Nat. Clin. Pract. Endocrinol. Metab. 3 2 (2007) 168-179
    • (2007) Nat. Clin. Pract. Endocrinol. Metab. , vol.3 , Issue.2 , pp. 168-179
    • de Kloet, E.R.1    Derijk, R.H.2    Meijer, O.C.3
  • 21
    • 20044395965 scopus 로고    scopus 로고
    • Stress and the brain: from adaptation to disease
    • de Kloet E.R., Joels M., and Holsboer F. Stress and the brain: from adaptation to disease. Nat. Rev. Neurosci. 6 6 (2005) 463-475
    • (2005) Nat. Rev. Neurosci. , vol.6 , Issue.6 , pp. 463-475
    • de Kloet, E.R.1    Joels, M.2    Holsboer, F.3
  • 22
    • 0033215376 scopus 로고    scopus 로고
    • Stress and cognition: are corticosteroids good or bad guys?
    • de Kloet E.R., Oitzl M.S., and Joels M. Stress and cognition: are corticosteroids good or bad guys?. Trends Neurosci. 22 10 (1999) 422-426
    • (1999) Trends Neurosci. , vol.22 , Issue.10 , pp. 422-426
    • de Kloet, E.R.1    Oitzl, M.S.2    Joels, M.3
  • 23
    • 0032467785 scopus 로고    scopus 로고
    • Brain corticosteroid receptor balance in health and disease
    • de Kloet E.R., Vreugdenhil E., Oitzl M.S., and Joels M. Brain corticosteroid receptor balance in health and disease. Endocrinol. Rev. 19 3 (1998) 269-301
    • (1998) Endocrinol. Rev. , vol.19 , Issue.3 , pp. 269-301
    • de Kloet, E.R.1    Vreugdenhil, E.2    Oitzl, M.S.3    Joels, M.4
  • 24
    • 0035032992 scopus 로고    scopus 로고
    • Corticoids in relation to fear, anxiety and psychopathology
    • Korte S.M. Corticoids in relation to fear, anxiety and psychopathology. Neurosci. Behav. Rev. 25 (2001) 117-142
    • (2001) Neurosci. Behav. Rev. , vol.25 , pp. 117-142
    • Korte, S.M.1
  • 25
    • 1642447172 scopus 로고    scopus 로고
    • BDNF serum concentrations in healthy volunteers are associated with depression-related personality traits
    • Lang U.E., Hellweg R., and Gallinat J. BDNF serum concentrations in healthy volunteers are associated with depression-related personality traits. Neuropsychopharmacology 29 4 (2004) 795-798
    • (2004) Neuropsychopharmacology , vol.29 , Issue.4 , pp. 795-798
    • Lang, U.E.1    Hellweg, R.2    Gallinat, J.3
  • 26
    • 0036321861 scopus 로고    scopus 로고
    • Memory mechanisms in posttraumatic stress disorder
    • Layton B., and Krikorian R. Memory mechanisms in posttraumatic stress disorder. J. Neuropsychiatry Clin. Neurosci. 14 3 (2002) 254-261
    • (2002) J. Neuropsychiatry Clin. Neurosci. , vol.14 , Issue.3 , pp. 254-261
    • Layton, B.1    Krikorian, R.2
  • 27
    • 0036113348 scopus 로고    scopus 로고
    • Stress and depression: possible links to neuron death in the hippocampus
    • Lee A.L., Ogle W.O., and Sapolsky R.M. Stress and depression: possible links to neuron death in the hippocampus. Bipolar Disord. 4 2 (2002) 117-128
    • (2002) Bipolar Disord. , vol.4 , Issue.2 , pp. 117-128
    • Lee, A.L.1    Ogle, W.O.2    Sapolsky, R.M.3
  • 28
    • 0036803673 scopus 로고    scopus 로고
    • Studies of hormone action in the hippocampal formation: possible relevance to depression and diabetes
    • McEwen B.S., Magarinos A.M., and Reagan L.P. Studies of hormone action in the hippocampal formation: possible relevance to depression and diabetes. J. Psychosom. Res. 53 4 (2002) 883-890
    • (2002) J. Psychosom. Res. , vol.53 , Issue.4 , pp. 883-890
    • McEwen, B.S.1    Magarinos, A.M.2    Reagan, L.P.3
  • 29
    • 0028894954 scopus 로고
    • Long-term antidepressant treatment reduces behavioural deficits in transgenic mice with impaired glucocorticoid receptor function
    • Montkowski A., Barden N., Wotjak C., Stec I., Ganster J., Meaney M., et al. Long-term antidepressant treatment reduces behavioural deficits in transgenic mice with impaired glucocorticoid receptor function. J. Neuroendocrinol. 7 11 (1995) 841-845
    • (1995) J. Neuroendocrinol. , vol.7 , Issue.11 , pp. 841-845
    • Montkowski, A.1    Barden, N.2    Wotjak, C.3    Stec, I.4    Ganster, J.5    Meaney, M.6
  • 31
    • 0037079060 scopus 로고    scopus 로고
    • Behavioral and neural analysis of extinction
    • Myers K.M., and Davis M. Behavioral and neural analysis of extinction. Neuron 36 4 (2002) 567-584
    • (2002) Neuron , vol.36 , Issue.4 , pp. 567-584
    • Myers, K.M.1    Davis, M.2
  • 32
    • 0030229916 scopus 로고    scopus 로고
    • The corticotropin-releasing factor (CRF) hypothesis of depression: new findings and new directions
    • Nemeroff C.B. The corticotropin-releasing factor (CRF) hypothesis of depression: new findings and new directions. Mol. Psychiatry 1 4 (1996) 336-342
    • (1996) Mol. Psychiatry , vol.1 , Issue.4 , pp. 336-342
    • Nemeroff, C.B.1
  • 34
    • 0034112299 scopus 로고    scopus 로고
    • Neurobiology of posttraumatic stress disorder
    • Newport D.J., and Nemeroff C.B. Neurobiology of posttraumatic stress disorder. Curr. Opin. Neurobiol. 10 (2000) 211-218
    • (2000) Curr. Opin. Neurobiol. , vol.10 , pp. 211-218
    • Newport, D.J.1    Nemeroff, C.B.2
  • 35
    • 2542495763 scopus 로고    scopus 로고
    • Inactivation of the glucocorticoid receptor in hepatocytes leads to fasting hypoglycemia and ameliorates hyperglycemia in streptozotocin-induced diabetes mellitus
    • Opherk C., Tronche F., Kellendonk C., Kohlmuller D., Schulze A., Schmid W., et al. Inactivation of the glucocorticoid receptor in hepatocytes leads to fasting hypoglycemia and ameliorates hyperglycemia in streptozotocin-induced diabetes mellitus. Mol. Endocrinol. 18 6 (2004) 1346-1353
    • (2004) Mol. Endocrinol. , vol.18 , Issue.6 , pp. 1346-1353
    • Opherk, C.1    Tronche, F.2    Kellendonk, C.3    Kohlmuller, D.4    Schulze, A.5    Schmid, W.6
  • 36
    • 0034460335 scopus 로고    scopus 로고
    • Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock
    • Reichardt H.M., Umland T., Bauer A., Kretz O., and Schutz G. Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock. Mol. Cell. Biol. 20 23 (2000) 9009-9017
    • (2000) Mol. Cell. Biol. , vol.20 , Issue.23 , pp. 9009-9017
    • Reichardt, H.M.1    Umland, T.2    Bauer, A.3    Kretz, O.4    Schutz, G.5
  • 37
    • 0034730465 scopus 로고    scopus 로고
    • The brain mineralocorticoid receptor: greedy for ligand, mysterious in function
    • Reul J.M., Gesing A., Droste S., Stec I.S., Weber A., Bachmann C., et al. The brain mineralocorticoid receptor: greedy for ligand, mysterious in function. Eur. J. Pharmacol. 405 1-3 (2000) 235-249
    • (2000) Eur. J. Pharmacol. , vol.405 , Issue.1-3 , pp. 235-249
    • Reul, J.M.1    Gesing, A.2    Droste, S.3    Stec, I.S.4    Weber, A.5    Bachmann, C.6
  • 38
    • 21544434047 scopus 로고    scopus 로고
    • Mice with genetically altered glucocorticoid receptor expression show altered sensitivity for stress-induced depressive reactions
    • Ridder S., Chourbaji S., Hellweg R., Urani A., Zacher C., Schmid W., et al. Mice with genetically altered glucocorticoid receptor expression show altered sensitivity for stress-induced depressive reactions. J. Neurosci. 25 26 (2005) 6243-6250
    • (2005) J. Neurosci. , vol.25 , Issue.26 , pp. 6243-6250
    • Ridder, S.1    Chourbaji, S.2    Hellweg, R.3    Urani, A.4    Zacher, C.5    Schmid, W.6
  • 39
    • 5344245987 scopus 로고    scopus 로고
    • Molecular mechanisms underlying emotional learning and memory in the lateral amygdala
    • Rodrigues S.M., Schafe G.E., and LeDoux J.E. Molecular mechanisms underlying emotional learning and memory in the lateral amygdala. Neuron 44 1 (2004) 75-91
    • (2004) Neuron , vol.44 , Issue.1 , pp. 75-91
    • Rodrigues, S.M.1    Schafe, G.E.2    LeDoux, J.E.3
  • 40
    • 33746409003 scopus 로고    scopus 로고
    • Toward an animal model of posttraumatic stress disorder
    • Siegmund A., and Wotjak C.T. Toward an animal model of posttraumatic stress disorder. Ann. N.Y. Acad. Sci. 1071 (2006) 324-334
    • (2006) Ann. N.Y. Acad. Sci. , vol.1071 , pp. 324-334
    • Siegmund, A.1    Wotjak, C.T.2
  • 41
    • 0029555826 scopus 로고
    • Effects of stress on neurotrophic factor expression in the rat brain
    • Smith M.A., Makino S., Kvetnansky R., and Post R.M. Effects of stress on neurotrophic factor expression in the rat brain. Ann. N.Y. Acad. Sci. 771 (1995) 234-239
    • (1995) Ann. N.Y. Acad. Sci. , vol.771 , pp. 234-239
    • Smith, M.A.1    Makino, S.2    Kvetnansky, R.3    Post, R.M.4
  • 42
    • 0032842478 scopus 로고    scopus 로고
    • Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety
    • Tronche F., Kellendonk C., Kretz O., Gass P., Anlag K., Orban P.C., et al. Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nat. Genet. 23 1 (1999) 99-103
    • (1999) Nat. Genet. , vol.23 , Issue.1 , pp. 99-103
    • Tronche, F.1    Kellendonk, C.2    Kretz, O.3    Gass, P.4    Anlag, K.5    Orban, P.C.6
  • 44
    • 19944386640 scopus 로고    scopus 로고
    • Mutant mouse models of depression: candidate genes and current mouse lines
    • Urani A., Chourbaji S., and Gass P. Mutant mouse models of depression: candidate genes and current mouse lines. Neurosci. Biobehav. Rev. 29 4-5 (2005) 805-828
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , Issue.4-5 , pp. 805-828
    • Urani, A.1    Chourbaji, S.2    Gass, P.3
  • 45
    • 0344442811 scopus 로고    scopus 로고
    • The neurotrophin hypothesis of depression revisited by transgenic mice
    • Urani A., Chourbaji S., Henn F., and Gass P. The neurotrophin hypothesis of depression revisited by transgenic mice. Clin. Neurosci. Res. 3 (2003) 263-269
    • (2003) Clin. Neurosci. Res. , vol.3 , pp. 263-269
    • Urani, A.1    Chourbaji, S.2    Henn, F.3    Gass, P.4
  • 46
    • 4143091546 scopus 로고    scopus 로고
    • Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability
    • Wei Q., Lu X.Y., Liu L., Schafer G., Shieh K.R., Burke S., et al. Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability. Proc. Natl. Acad. Sci. U.S.A. 101 32 (2004) 11851-11856
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , Issue.32 , pp. 11851-11856
    • Wei, Q.1    Lu, X.Y.2    Liu, L.3    Schafer, G.4    Shieh, K.R.5    Burke, S.6
  • 47
    • 0036642255 scopus 로고    scopus 로고
    • Knockout mice: simple solutions to the problems of genetic background and flanking genes
    • Wolfer D.P., Crusio W.E., and Lipp H.P. Knockout mice: simple solutions to the problems of genetic background and flanking genes. Trends Neurosci. 25 7 (2002) 336-340
    • (2002) Trends Neurosci. , vol.25 , Issue.7 , pp. 336-340
    • Wolfer, D.P.1    Crusio, W.E.2    Lipp, H.P.3
  • 48
    • 0035348160 scopus 로고    scopus 로고
    • Research and treatment approaches to depression
    • Wong M.L., and Licinio J. Research and treatment approaches to depression. Nat. Rev. Neurosci. 2 5 (2001) 343-351
    • (2001) Nat. Rev. Neurosci. , vol.2 , Issue.5 , pp. 343-351
    • Wong, M.L.1    Licinio, J.2
  • 49
    • 0037330692 scopus 로고    scopus 로고
    • Synthesis of novel arylpyrazolo corticosteroids as potential ligands for imaging brain glucocorticoid receptors
    • Wüst F., Carlson K.E., and Katzenellenbogen J.A. Synthesis of novel arylpyrazolo corticosteroids as potential ligands for imaging brain glucocorticoid receptors. Steroids 68 (2003) 177-191
    • (2003) Steroids , vol.68 , pp. 177-191
    • Wüst, F.1    Carlson, K.E.2    Katzenellenbogen, J.A.3
  • 50
    • 33746433010 scopus 로고    scopus 로고
    • Advances in understanding neuroendocrine alterations in PTSD and their therapeutic implications
    • Yehuda R. Advances in understanding neuroendocrine alterations in PTSD and their therapeutic implications. Ann. N.Y. Acad. Sci. 1071 (2006) 137-166
    • (2006) Ann. N.Y. Acad. Sci. , vol.1071 , pp. 137-166
    • Yehuda, R.1


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