GRKO mice express an aberrant dexamethasone-binding glucocorticoid receptor, but are profoundly glucocorticoid resistant

Molecular and Cellular Endocrinology

Volumn 173, Issue 1-2, 2001, Pages 193-202

  Cole, Timothy J ^a   Myles, Kathy ^a   Purton, Jared F ^a,b   Brereton, Phillip S ^a   Solomon, Nicola M ^a   Godfrey, Dale I ^b   Funder, John W ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Gene targeting; Glucocorticoid receptors; Glucocorticoids

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; MESSENGER RNA;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CELL CULTURE; CONTROLLED STUDY; EXON; FETUS; GENE INSERTION; GENE LOCUS; HORMONE RESISTANCE; IMMUNOBLOTTING; IN VITRO STUDY; KIDNEY; KNOCKOUT MOUSE; LIVER; LIVER CELL; LUNG; MOUSE; MUTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR BINDING; THYMOCYTE;

ADRENALECTOMY; ANIMALS; BLOTTING, WESTERN; CELL DEATH; CELL EXTRACTS; DEXAMETHASONE; DRUG RESISTANCE; ENZYME INDUCTION; GENE DELETION; GLUCOCORTICOIDS; GLUCOSE-6-PHOSPHATASE; HEPATOCYTES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEASE PROTECTION ASSAYS; PHENOTYPE; POLYMERASE CHAIN REACTION; RECEPTORS, GLUCOCORTICOID; RNA, MESSENGER; THYMUS GLAND;

EID: 0035931996     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(00)00407-X     Document Type: Article

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