Blockade of alcohol's amnestic activity in humans by an α5 subtype benzodiazepine receptor inverse agonist

Neuropharmacology

Volumn 53, Issue 7, 2007, Pages 810-820

  Nutt, David J ^a   Besson, Marie ^a   Wilson, Susan J ^a   Dawson, Gerard R ^b   Lingford Hughes, Anne R ^b  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

5 subtype; Alcohol; Benzodiazepine; Inverse agonist; Memory

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ALCOHOL; BENZODIAZEPINE RECEPTOR ALPHA5; BENZODIAZEPINE RECEPTOR INVERSE STIMULATING AGENT; PLACEBO; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ADULT; ALCOHOL INTOXICATION; AMNESIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; EYE MOVEMENT; HUMAN; HUMAN EXPERIMENT; MALE; MEMORY; NORMAL HUMAN; PRIORITY JOURNAL; SEDATION; TRANQUILIZING ACTIVITY; WORD LIST RECALL;

ADULT; AFFINITY LABELS; ALCOHOLS; AMNESIA; ANTI-ANXIETY AGENTS; AZIDES; BENZODIAZEPINES; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; GABA AGONISTS; HUMANS; MALE; MODELS, BIOLOGICAL; NEUROPSYCHOLOGICAL TESTS; SEVERITY OF ILLNESS INDEX; SLEEP; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 36248952127     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2007.08.008     Document Type: Article

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