A high affinity ligand for GABAA-receptor containing α5 subunit antagonizes ethanol's neurobehavioral effects in Long-Evans rats

Psychopharmacology

Volumn 172, Issue 4, 2004, Pages 455-462

  McKay, Peter F ^a   Foster, Katrina L ^a   Mason, Dynesha ^a   Cummimgs, Rancia ^a   Garcia, Marin ^a   Williams, La Shone ^a   Grey, Collette ^d   McCane, Shannan ^a   He, Xiaohui ^b   Cook, James M ^b   June, Harry L ^a,c  

^a INDIANA UNIVERSITY   (United States)

^b UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NONE

Author keywords

; Aminobutyric acid type A (GABA ) receptor; Alcohol reinforcement; Alcohol sedation; Locomotor activity; Motor impairing effects; Subunit

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; ALCOHOL; BENZODIAZEPINE RECEPTOR INVERSE STIMULATING AGENT; LIGAND; RY 024; UNCLASSIFIED DRUG; WATER;

ALCOHOL BLOOD LEVEL; ALCOHOLISM; ALPHA CHAIN; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ALCOHOL INTERACTION; DRUG RECEPTOR BINDING; LIGAND BINDING; LOCOMOTION; MALE; MOTOR DYSFUNCTION; NONHUMAN; OPEN FIELD BEHAVIOR; OSCILLATION; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; REINFORCEMENT; SEDATION;

ANIMALS; BEHAVIOR, ANIMAL; BENZODIAZEPINES; DRUG INTERACTIONS; ETHANOL; LIGANDS; MALE; MOTOR ACTIVITY; PROTEIN SUBUNITS; RATS; RATS, LONG-EVANS; RECEPTORS, GABA-A; REINFORCEMENT (PSYCHOLOGY);

EID: 2442585177     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-003-1671-z     Document Type: Article

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