PAR-2 activation at the time of reperfusion salvages myocardium via an ERK1/2 pathway in in vivo rat hearts

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 293, Issue 5, 2007, Pages

  Jiang, Rong ^a   Zatta, Amanda ^a   Kin, Hajime ^a   Wang, Ningping ^a   Reeves, James G ^a   Mykytenko, James ^a   Deneve, Jeremiah ^a   Zhao, Zhi Qing ^a   Guyton, Robert A ^a   Vinten Johansen, Jakob ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Infarct size; Protein kinases; Reperfusion injury

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; CHELERYTHRINE; DIMETHYL SULFOXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PEPTIDE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN BAD; PROTEIN KINASE B; PROTEIN KINASE C; PROTEINASE ACTIVATED RECEPTOR 2; SERYLLEUCYLISOLEUCYLGLYCYLARGINYLLEUCINAMIDE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HEART INFARCTION SIZE; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TIME; WESTERN BLOTTING;

ANIMALS; ENZYME ACTIVATION; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, PAR-2;

EID: 36148993325     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00209.2007     Document Type: Article

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