Sensitive fluorescence polarization technique for rapid screening of α-synuclein oligomerization/fibrillization inhibitors

Biochemistry

Volumn 46, Issue 44, 2007, Pages 12522-12529

  Luk, Kelvin C ^a   Hyde, Edward G ^a   Trojanowski, John Q ^a   Lee, Virginia M Y ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; DISEASES; FLUORESCENCE; MOLECULAR MASS; OLIGOMERIZATION;

AMYLOID DYES; FLUORESCENCE POLARIZATION (FP); PARKINSON'S DISEASE; PATHOGENESIS;

ENZYME INHIBITION;

ALPHA SYNUCLEIN; AMYLOID;

ARTICLE; CONTROLLED STUDY; DIFFUSE LEWY BODY DISEASE; DISEASE COURSE; FLUORESCENCE POLARIZATION; GENE MUTATION; HUMAN; LEWY BODY; MOLECULAR WEIGHT; MOTOR DYSFUNCTION; NERVE DEGENERATION; NONHUMAN; OLIGOMERIZATION; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY;

ALPHA-SYNUCLEIN; ANTIOXIDANTS; ANTIPARKINSON AGENTS; DIMERIZATION; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; EPINEPHRINE; FLAVANONES; FLUORESCENCE POLARIZATION; FLUORESCENT DYES; LEVODOPA; NEUROFIBRILS; NOREPINEPHRINE; POLYMERS;

EID: 35848966149     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi701128c     Document Type: Article

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