A comparison of amyloid fibrillogenesis using the novel fluorescent compound K114

Journal of Neurochemistry

Volumn 86, Issue 6, 2003, Pages 1359-1368

  Crystal, Adam S ^a   Giasson, Benoit I ^a   Crowe, Alexander ^a   Kung, Mei Ping ^a   Zhuang, Zhi Ping ^a   Trojanowski, John Q ^a   Lee, Virginia M Y ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Amyloid; Amyloid dye; Congo Red; K114; Synuclein; Tau

Indexed keywords

1 BROMO 2,5 BIS(4 HYDROXY)STYRYLBENZENE; ALPHA SYNUCLEIN; AMYLOID; AMYLOID BETA PROTEIN; BENZENE DERIVATIVE; CONGO RED; DIRECT YELLOW 7; FLUORESCENT DYE; MONOMER; TAU PROTEIN; THIOFLAVINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CELL INCLUSION; CHEMICAL STRUCTURE; DEGENERATIVE DISEASE; HISTOLOGY; HUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; QUANTITATIVE ANALYSIS; STRUCTURE ANALYSIS;

ALPHA-SYNUCLEIN; AMYLOID; CONGO RED; FLUORESCENT DYES; HUMANS; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, FLUORESCENCE; STAINING AND LABELING; STYRENES; SYNUCLEINS; TAU PROTEINS;

ANIMALIA;

EID: 0141543878     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01949.x     Document Type: Article

References (43)

1. Agdeppa E. D., Kepe V., Liu J., Flores-Torres S., Satyamurthy N., Petric A., Cole G. M., Small G. W., Huang S. C. and Barrio J. R. (2001) Binding characteristics of radiofluorinated 6-dialkylamino-2-naphthylethylidene derivatives as positron emission tomography imaging probes for beta-amyloid plaques in Alzheimer's disease. J. Neurosci. 21, RC189 (1-5).
2. Bronfman F. C., Carrido J., Alvarez A., Morgan C. and Inestrosa N. C. (1996) Laminin inhibits amyloid-beta-peptide fibrillation. Neurosci. Lett. 218, 201-203.
3. Bucciantini M., Giannoni E., Chiti F., Baroni F., Formigli L., Zurdo J., Taddei N., Ramponi G., Dobson C. M. and Stefani M. (2002) Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature 416, 507-511.
4. Carter D. B. and Chou K. C. (1998) A model for structure-dependent binding of Congo red to Alzheimer beta-amyloid fibrils. Neurobiol. Aging 19, 37-40.
5. Conway K. A., Rochet J. C., Bieganski R. M. and Lansbury P. T. Jr (2001) Kinetic stabilization of the alpha-synuclein protofibril by a dopamine- alpha-synuclein adduct. Science 294, 1346-1349.
6. Eanes E. D. and Glenner G. G. (1968) X-ray diffraction studies on amyloid filaments. J. Histochem. Cytochem. 16, 673-677.
7. Fezoui Y., Hartley D. M., Harper J. D., Khurana R., Walsh D. M., Condron M. M., Selkoe D. J., Lansbury P. T. Jr, Fink A. L. and Teplow D. B. (2000) An improved method of preparing the amyloid beta-protein for fibrillogenesis and neurotoxicity experiments. Amyloid 7, 166-178.
8. Giasson B. I., Uryu K., Trojanowski J. Q. and Lee V. M.-Y. (1999) Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro. J. Biol. Chem. 274, 7619-7622.
9. Giasson B. I., Murray I. V., Trojanowski J. Q. and Lee V. M.-Y. (2001) A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly. J. Biol. Chem. 276, 2380-2386.
10. Glenner G. G. (1980) Amyloid deposits and amyloidosis. The beta-fibrilloses (first of two parts). N. Engl. J. Med. 302, 1283-1292.
11. Glenner G. G., Eanes E. D., Bladen H. A., Linke R. P. and Termine J. D. (1974) Beta-pleated sheet fibrils. A comparison of native amyloid with synthetic protein fibrils. J. Histochem. Cytochem. 22, 1141-1158.
12. Goedert M. (2001) Alpha-synuclein and neurodegenerative diseases. Nat. Rev. Neurosci. 2, 492-501.
13. Goedert M., Jakes R., Spillantini M. G., Hasegawa M., Smith M. J. and Crowther R. A. (1996) Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Nature 383, 550-553.
14. Goldberg M. S. and Lansbury P. T. (2000) Is there a cause-and-effect relationship between α-synuclein fibrillization and Parkinson's disease? Nat. Cell Biol, 2, E115-E119.
15. Goldsbury C. S., Wirtz S., Muller S. A., Sunderji S., Wicki P., Aebi U. and Frey P. (2000) Studies on the in vitro assembly of a beta 1-40: implications for the search for a beta fibril formation inhibitors. J. Struct. Biol. 130, 217-231.
16. Gordon D. J., Sciarretta K. L., and Meredith S. C. (2001) Inhibition of beta-amyloid (40) fibrillogenesis and disassembly of beta-amyloid (40) fibrils by short beta-amyloid congeners containing N-methyl amino acids at alternate residues. Biochemistry 40, 8237-8245.
17. Hardy J. and Selkoe D. J. (2002) The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353-356.
18. Hong M. et al. (1998) Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17. Science 282, 1914-1917.
19. Inestrosa N. C., Alvarez A., Perez C. A., Moreno R. D., Vicente M., Linker C., Casanueva O. I., Soto C. and Garrido J. (1996) Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme. Neuron 16, 881-891.
20. Kayed R., Head E., Thompson J. L., McIntire T. M., Milton S. C., Cotman C. W. and Glade C. G. (2003) Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300, 486-489.
21. Klunk W. E., Pettegrew J. W. and Abraham D. J. (1989) Quantitative evaluation of congo red binding to amyloid-like proteins with a beta-pleated sheet conformation. J. Histochem. Cytochem. 37, 1273-1281.
22. Klunk W. E., Debnath M. L. and Pettegrew J. W. (1995) Chrysamine-G binding to Alzheimer and control brain: autopsy study of a new amyloid probe. Neurobiol. Aging 16, 541-548.
23. Klunk W. E., Jacob R. F. and Mason R. P. (1999a) Quantifying amyloid beta-peptide (Abeta) aggregation using the Congo red-Abeta (CR-abeta) spectrophotometric assay. Anal. Biochem. 266, 66-76.
24. Klunk W. E., Jacob R. F. and Mason R. P. (1999b) Quantifying amyloid by congo red spectral shift assay. Meth Enzymol. 309, 285-305.
25. Klunk W. E., Wang Y., Huang G. F., Debnath M. L., Holt D. P. and Mathis C. A. (2001) Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain. Life Sci. 69, 1471-1484.
26. Klunk W. E., Bacskai B. J., Mathis C. A., Kajdasz S. T., McLellan M. E., Frosch M. P., Debnath M. L., Holt D. P., Wang Y. and Hyman B. T., (2002) Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative. J. Neuropathol. Exp. Neurol. 61, 797-805.
27. Kung M. P., Hou C., Zhuang Z. P., Skovronsky D. M., Zhang B., Gur T. L., Trojanowski J. Q., Lee V. M.-Y. and Kung H. F. (2002) Radioiodinated styrylbenzene derivatives as potential SPECT imaging agents for amyloid plaque detection in Alzheimer's disease. J. Mol. Neurosci. 19, 7-10.
28. Lashuel H. A., Hartley D., Petre B. M., Walz T. and Lansbury P. T. (2002) Neurodegenerative disease: Amyloid pores from pathogenic mutations. Nature 418, 291.
29. Lee C. W., Zhuang Z. P., Kung M. P., Plossl K., Skovronsky D., Gur T., Hou C., Trojanowski J. Q., Lee V. M.-Y. and Kung H. F. (2001a) Isomerization of (Z,Z) to (E, E)1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene in strong base: probes for amyloid plaques in the brain. J. Med. Chem. 44, 2270-2275.
30. Lee V. M.-Y., Goedert M. and Trojanowski J. Q. (2001b) Neurodegenerative tauopathies. Annu. Rev. Neurosci, 24, 1121-1159.
31. LeVine H. III (1993) Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution. Protein Sci. 2, 404-410.
32. LeVine H. III (1999) Quantification of beta-sheet amyloid fibril structures with thioflavin T. Meth Enzymol. 309, 274-284.
33. Naiki H., Higuchi K., Hosokawa M. and Takeda T. (1989) Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavin T. Anal. Biochem. 177, 244-249.
34. Schmidt M. L. et al. (2001) The fluorescent Congo red derivative, (trans,trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene (BSB), labels diverse beta-pleated sheet structures in postmortem human neurodegenerative disease brains. Am. J. Pathol. 159, 937-943.
35. Selkoe D. J. (1999) Translating cell biology into therapeutic advances in Alzheimer's disease. Nature 399, A23-A31.
36. Serpell L. C., Berriman J., Jakes R., Goedert M. and Crowther R. A. (2000) Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid- like cross-beta conformation. Proc. Natl Acad. Sci. USA 97, 4897-4902.
37. Skovronsky D. M., Zhang B., Kung M. P., Kung H. F., Trojanowski J. Q. and Lee V. M.-Y. (2000) In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease. Proc. Natl Acad. Sci. USA 97, 7609-7614.
38. Spillantini M. G. and Goedert M. (1998) Tau protein pathology in neurodegenerative diseases. Trends Neurosci. 21, 428-433.
39. Spillantini M. G., Schmidt M. L., Lee V. M.-Y., Trojanowski J. Q., Jakes R. and Goedert M. (1997) Alpha-synuclein in Lewy bodies. Nature 388, 839-840.
40. Styren S. D., Hamilton R. L., Styren G. C. and Klunk W. E. (2000) X-34, a fluorescent derivative of Congo red: a novel histochemical stain for Alzheimer's disease pathology. J. Histochem. Cytochem. 48, 1223-1232.
41. Taylor J. P., Hardy J. and Fischbeck K. H. (2002) Toxic proteins in neurodegenerative disease. Science 296, 1991-1995.
42. Trojanowski J. Q. and Lee V. M.-Y. (2000) 'Fatal attractions' of proteins. A comprehensive hypothetical mechanism underlying Alzheimer's disease and other neurodegenerative disorders. Ann. N. Y. Acad. Sci. 924, 62-67.
43. Zhuang Z. P., Kung M. P., Hou C., Skovronsky D. M., Gur T. L., Plossl K., Trojanowski J. Q., Lee V. M.-Y. and Kung H. F. (2001) Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates. J. Med. Chem. 44, 1905-1914.