Intravenous siRNA of brain cancer with receptor targeting and avidin-biotin technology

Pharmaceutical Research

Volumn 24, Issue 12, 2007, Pages 2309-2316

  Xia, Chun Fang ^a   Zhang, Yufeng ^b   Zhang, Yun ^a,b   Boado, Ruben J ^a,b   Pardridge, William M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ArmaGen Technologies Inc   (United States)

Author keywords

Avidin; Biotin; Blood brain barrier; Monoclonal antibody; RNA interference

Indexed keywords

AVIDIN; BIOTIN; LUCIFERASE; MONOCLONAL ANTIBODY; SMALL INTERFERING RNA; STREPTAVIDIN;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CANCER; BRAIN CAPILLARY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; GENE EXPRESSION; GENETIC TRANSFECTION; GLIA CELL; IMPLANT; IN VIVO STUDY; INTRACRANIAL TUMOR; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

ANIMALS; ANTIBODIES, MONOCLONAL; BIOTIN; BIOTINYLATION; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; CELL LINE, TUMOR; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENES, REPORTER; HUMANS; LUCIFERASES; MALE; RATS; RATS, INBRED F344; RECEPTOR, INSULIN; RECEPTORS, TRANSFERRIN; RNA INTERFERENCE; RNA, SMALL INTERFERING; STREPTAVIDIN; TIME FACTORS; TRANSFECTION;

EID: 35848935409     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-007-9460-8     Document Type: Article

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