Possible involvement of atypical protein kinase C (PKC) in glucose- sensitive expression of the human insulin gene: DNA-binding activity and transcriptional activity of pancreatic and duodenal homeobox gene-1 (PDX-1) are enhanced via calphostin C-sensitive but phorbol 12-myristate 13-acetate (PMA) and Go 6976-insensitive pathway

Endocrine Journal

Volumn 46, Issue 1, 1999, Pages 43-58

  Furukawa, Noboru ^a   Shirotani, Tetsuya ^a   Araki, Eiichi ^a   Kaneko, Kengo ^a   Todaka, Mikio ^a   Matsumoto, Kazuya ^a   Tsuruzoe, Kaku ^a   Motoshima, Hiroyuki ^a   Yoshizato, Kazuaki ^a   Kishikawa, Hideki ^a   Shichiri, Motoaki ^a  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Atypical protein kinase C; Insulin gene expression; MIN6 cell; Pancreatic and duodenal homeobox gene 1 (PDX 1)

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; CALPHOSTIN C; INSULIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C;

ARTICLE; DNA BINDING; ENZYME ACTIVATION; HOMEOBOX; HUMAN; IMMUNOCYTOCHEMISTRY; INSULIN SYNTHESIS; PROMOTER REGION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; TRANSCRIPTION REGULATION;

EID: 0032926648     PISSN: 09188959     EISSN: None     Source Type: Journal    
DOI: 10.1507/endocrj.46.43     Document Type: Article

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