메뉴 건너뛰기




Volumn 44, Issue 2, 2007, Pages 107-112

Analysis of molecular fingerprint and virulence factors of Helicobacter pylori strains;Análise das impressões digitais de DNA e de fatores de virulência de linhagens de Helicobacter pylori

Author keywords

Antigens; Bacterial; Bacterial proteins; DNA fingerprints; Helicobacter infections; Helicobacter pylori

Indexed keywords

CAGA PROTEIN; VACUOLATING TOXIN; VIRULENCE FACTOR;

EID: 35649017239     PISSN: 00042803     EISSN: 16784219     Source Type: Journal    
DOI: 10.1590/s0004-28032007000200004     Document Type: Article
Times cited : (4)

References (62)
  • 1
    • 0026675742 scopus 로고
    • DNA diversity among clinical isolates of Helicobacter pylori detected by PCR-based RAPD fingerprinting
    • Akopyanz N, Bukanov NO, Westblom TU, Kresovich S, Berg DE. DNA diversity among clinical isolates of Helicobacter pylori detected by PCR-based RAPD fingerprinting. Nucleic Acids Res. 1992;20:5137-42.
    • (1992) Nucleic Acids Res , vol.20 , pp. 5137-5142
    • Akopyanz, N.1    Bukanov, N.O.2    Westblom, T.U.3    Kresovich, S.4    Berg, D.E.5
  • 4
    • 0029059733 scopus 로고
    • Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of especific vacA types with cytotoxin production and peptic ulceration
    • Atherton JC, Cao P, Peek RM, Tummuru MK, Blaser MJ, Cover TL. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of especific vacA types with cytotoxin production and peptic ulceration. J Biol Chem. 1995;270:17771-7.
    • (1995) J Biol Chem , vol.270 , pp. 17771-17777
    • Atherton, J.C.1    Cao, P.2    Peek, R.M.3    Tummuru, M.K.4    Blaser, M.J.5    Cover, T.L.6
  • 5
    • 0031032033 scopus 로고    scopus 로고
    • Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori
    • Atherton JC, Peek RM, Tham KT, Cover TL, Blaser MJ. Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori. Gastroenterology. 1997;112:92-9.
    • (1997) Gastroenterology , vol.112 , pp. 92-99
    • Atherton, J.C.1    Peek, R.M.2    Tham, K.T.3    Cover, T.L.4    Blaser, M.J.5
  • 6
    • 0027443618 scopus 로고
    • Evaluation of the polymerase chain reaction for detecting the urease C gene of Helicobacter pylori in gastric biopsy samples and dental plaque
    • Bickley J, Owen RJ, Fraser AG, Pounder RE. Evaluation of the polymerase chain reaction for detecting the urease C gene of Helicobacter pylori in gastric biopsy samples and dental plaque. J Med Microbiol. 1993;39:338-44.
    • (1993) J Med Microbiol , vol.39 , pp. 338-344
    • Bickley, J.1    Owen, R.J.2    Fraser, A.G.3    Pounder, R.E.4
  • 8
    • 0029043658 scopus 로고
    • Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach
    • Blaser MJ, Perez-Perez GI, Kleanthous H, Cover TL, Peek RM, Chyou PH, Stemmermann GN, Nomura A. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res. 1995;55:2111-5.
    • (1995) Cancer Res , vol.55 , pp. 2111-2115
    • Blaser, M.J.1    Perez-Perez, G.I.2    Kleanthous, H.3    Cover, T.L.4    Peek, R.M.5    Chyou, P.H.6    Stemmermann, G.N.7    Nomura, A.8
  • 9
    • 0028242210 scopus 로고
    • Ordered cosmid library and high-resolution physical-genetic map of Helicobacter pylori strain NCTC11638
    • Bukanov NO, Berg DE. Ordered cosmid library and high-resolution physical-genetic map of Helicobacter pylori strain NCTC11638. Mol Microbiol. 1994;11:509-23.
    • (1994) Mol Microbiol , vol.11 , pp. 509-523
    • Bukanov, N.O.1    Berg, D.E.2
  • 10
    • 0032728091 scopus 로고    scopus 로고
    • Performance criteria of DNA fingerprinting methods for typing of Helicobacter pylori isolates: Experimental results and meta-analysis
    • Burucoa C, Lhomme V, Fauchere JL. Performance criteria of DNA fingerprinting methods for typing of Helicobacter pylori isolates: experimental results and meta-analysis. J Clin Microbiol. 1999;37:4071-80.
    • (1999) J Clin Microbiol , vol.37 , pp. 4071-4080
    • Burucoa, C.1    Lhomme, V.2    Fauchere, J.L.3
  • 12
    • 0026739795 scopus 로고
    • Purification and characterization of the vacuolating toxin from Helicobacter pylori
    • Cover TL, Blaser MJ. Purification and characterization of the vacuolating toxin from Helicobacter pylori. J Biol Chem. 1992;267:10570-5.
    • (1992) J Biol Chem , vol.267 , pp. 10570-10575
    • Cover, T.L.1    Blaser, M.J.2
  • 13
    • 0037373880 scopus 로고    scopus 로고
    • Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin
    • Cover TL, Krishna US, Israel DA, Peek RM Jr. Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin. Cancer Res. 2003;63:951
    • (2003) Cancer Res , vol.63 , pp. 951
    • Cover, T.L.1    Krishna, U.S.2    Israel, D.A.3    Peek Jr., R.M.4
  • 15
    • 0028303833 scopus 로고
    • Helicobacter pylori gastritis and primary gastric non-Hodgkin's lymphomas
    • Eidt S, Stolte M, Fischer R. Helicobacter pylori gastritis and primary gastric non-Hodgkin's lymphomas. J Clin Pathol. 1994;47:436-9.
    • (1994) J Clin Pathol , vol.47 , pp. 436-439
    • Eidt, S.1    Stolte, M.2    Fischer, R.3
  • 16
    • 0031686933 scopus 로고    scopus 로고
    • Helicobacter pylori cagA status and s and m alleles of vacA in isolates from individuals with a variety of H. pylori-associated gastric diseases
    • Evans DG, Queiroz DM, Mendes EN, Evans DJ Jr. Helicobacter pylori cagA status and s and m alleles of vacA in isolates from individuals with a variety of H. pylori-associated gastric diseases. J Clin Microbiol. 1998;36:3435-7.
    • (1998) J Clin Microbiol , vol.36 , pp. 3435-3437
    • Evans, D.G.1    Queiroz, D.M.2    Mendes, E.N.3    Evans Jr., D.J.4
  • 17
    • 17644434620 scopus 로고    scopus 로고
    • Association of Helicobacter pylori genotype with gastroesophageal reflux disease and other upper gastrointestinal disease
    • Fallone CA, Barkun AN, Friedman G, Mayrand S, Loo V, Beech R, Best L, Joseph L.. Association of Helicobacter pylori genotype with gastroesophageal reflux disease and other upper gastrointestinal disease. Am J Gastroenterol. 2000;95:659-69.
    • (2000) Am J Gastroenterol , vol.95 , pp. 659-669
    • Fallone, C.A.1    Barkun, A.N.2    Friedman, G.3    Mayrand, S.4    Loo, V.5    Beech, R.6    Best, L.7    Joseph, L.8
  • 18
    • 0029911612 scopus 로고    scopus 로고
    • Effects of aging and gastritis on gastric acid and pepsin secretion in humans: A prospective study
    • Feldman M, Cryer B, McArthur KE, Huet BA, Lee E. Effects of aging and gastritis on gastric acid and pepsin secretion in humans: a prospective study. Gastroenterology. 1996;110:1043-52.
    • (1996) Gastroenterology , vol.110 , pp. 1043-1052
    • Feldman, M.1    Cryer, B.2    McArthur, K.E.3    Huet, B.A.4    Lee, E.5
  • 20
    • 0028261929 scopus 로고
    • Intracellular Campylobacter-like organism from ferrets and hamsters with proliferative bowel disease is a Desulfovibrio sp
    • Fox JG, Dewhirst FE, Fraser GJ, Paster BJ, Shames B, Murphy JC. Intracellular Campylobacter-like organism from ferrets and hamsters with proliferative bowel disease is a Desulfovibrio sp. J Clin Microbiol. 1994;32:1229-37.
    • (1994) J Clin Microbiol , vol.32 , pp. 1229-1237
    • Fox, J.G.1    Dewhirst, F.E.2    Fraser, G.J.3    Paster, B.J.4    Shames, B.5    Murphy, J.C.6
  • 22
    • 9444223670 scopus 로고    scopus 로고
    • Helicobacter pylori vacuolating cytotoxin: From cellular vacuolation to immunosuppressive activities
    • Gebert B, Fischer W, Haas R. Helicobacter pylori vacuolating cytotoxin: from cellular vacuolation to immunosuppressive activities. Rev Physiol Biochem Pharmacol. 2004;152:205-20.
    • (2004) Rev Physiol Biochem Pharmacol , vol.152 , pp. 205-220
    • Gebert, B.1    Fischer, W.2    Haas, R.3
  • 23
    • 0031899363 scopus 로고    scopus 로고
    • Proteins encoded by the cag pathogenicity island of Helicobacter pylori are required for NF-kappaB activation
    • Glocker E, Lange C, Covacci A, Bereswill S, Kist M, Pahl HL. Proteins encoded by the cag pathogenicity island of Helicobacter pylori are required for NF-kappaB activation. Infect Immun. 1998;66:2346-8.
    • (1998) Infect Immun , vol.66 , pp. 2346-2348
    • Glocker, E.1    Lange, C.2    Covacci, A.3    Bereswill, S.4    Kist, M.5    Pahl, H.L.6
  • 24
    • 0029078062 scopus 로고    scopus 로고
    • Go MF, Chan KY, Versalovic J, Koeuth T, Graham DY, Lupski JR. Cluster analysis of Helicobacter pylori genomic DNA fingerprints suggests gastroduodenal disease-specific associations. scand J Gastroenterol. 1995;30:640-6.
    • Go MF, Chan KY, Versalovic J, Koeuth T, Graham DY, Lupski JR. Cluster analysis of Helicobacter pylori genomic DNA fingerprints suggests gastroduodenal disease-specific associations. scand J Gastroenterol. 1995;30:640-6.
  • 25
    • 0029935007 scopus 로고    scopus 로고
    • Population genetic analysis of Helicobacter pylori by multilocus enzyme electrophoresis: Extensive allelic diversity and recombinational population structure
    • Go MF, Kapur V, Graham DY, Musser JM. Population genetic analysis of Helicobacter pylori by multilocus enzyme electrophoresis: extensive allelic diversity and recombinational population structure. J Bacteriol. 1996;178:3934-8.
    • (1996) J Bacteriol , vol.178 , pp. 3934-3938
    • Go, M.F.1    Kapur, V.2    Graham, D.Y.3    Musser, J.M.4
  • 27
    • 0031724261 scopus 로고    scopus 로고
    • The significance of cagA and vacA subtypes of Helicobacter pylori in the pathogenesis of inflammation and peptic ulceration
    • Gunn MC, Stephens JC, Stewart JA, Rathbone BJ, West KP. The significance of cagA and vacA subtypes of Helicobacter pylori in the pathogenesis of inflammation and peptic ulceration. J Clin Pathol. 1998;51:761-4.
    • (1998) J Clin Pathol , vol.51 , pp. 761-764
    • Gunn, M.C.1    Stephens, J.C.2    Stewart, J.A.3    Rathbone, B.J.4    West, K.P.5
  • 28
    • 0141718417 scopus 로고    scopus 로고
    • stability of randomly amplified polymorphic DNA fingerprinting in genotyping clinical isolates of Helicobacter pylori
    • Han FC, Ng HC, Ho B. stability of randomly amplified polymorphic DNA fingerprinting in genotyping clinical isolates of Helicobacter pylori. World J Gastroenterol. 2003 9:2021-4.
    • (2003) World J Gastroenterol , vol.9 , pp. 2021-2024
    • Han, F.C.1    Ng, H.C.2    Ho, B.3
  • 30
    • 0035022272 scopus 로고    scopus 로고
    • Clustering of south African Helicobacter pylori isolates from peptic ulcer disease patients is demonstrated by repetitive extragenic palindromic-PCR fingerprinting
    • Kidd M, Atherton JC, Lastovica AJ, Louw JA. Clustering of south African Helicobacter pylori isolates from peptic ulcer disease patients is demonstrated by repetitive extragenic palindromic-PCR fingerprinting. J Clin Microbiol. 2001;9:1833-9.
    • (2001) J Clin Microbiol , vol.9 , pp. 1833-1839
    • Kidd, M.1    Atherton, J.C.2    Lastovica, A.J.3    Louw, J.A.4
  • 32
    • 0030821856 scopus 로고    scopus 로고
    • Helicobacter pylori in gastro-oesophageal reflux disease: Causal agent, independent or protective factor?
    • Labenz J, Malfertheiner P. Helicobacter pylori in gastro-oesophageal reflux disease: causal agent, independent or protective factor? Gut.1997;41:277-80.
    • (1997) Gut , vol.41 , pp. 277-280
    • Labenz, J.1    Malfertheiner, P.2
  • 33
    • 0033761176 scopus 로고    scopus 로고
    • Colonization with cagA-positive Helicobacter pylori strains inversely associated with reflux esophagitis and Barrett's esophagus
    • Loffeld RJ, Werdmuller BF, Kusters JG, Perez-Perez GI, Blaser MJ, Kuipers EJ. Colonization with cagA-positive Helicobacter pylori strains inversely associated with reflux esophagitis and Barrett's esophagus. Digestion. 2000;62:95-9.
    • (2000) Digestion , vol.62 , pp. 95-99
    • Loffeld, R.J.1    Werdmuller, B.F.2    Kusters, J.G.3    Perez-Perez, G.I.4    Blaser, M.J.5    Kuipers, E.J.6
  • 34
    • 0029800122 scopus 로고    scopus 로고
    • Genetic diversity of Helicobacter pylori
    • Logan RP, Berg DE. Genetic diversity of Helicobacter pylori. Lancet. 1996;348:1462-3.
    • (1996) Lancet , vol.348 , pp. 1462-1463
    • Logan, R.P.1    Berg, D.E.2
  • 35
    • 0021259505 scopus 로고
    • Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration
    • Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet. 1984;1:1311-4.
    • (1984) Lancet , vol.1 , pp. 1311-1314
    • Marshall, B.J.1    Warren, J.R.2
  • 37
    • 0034583821 scopus 로고    scopus 로고
    • Prevalence of Helicobacter pylori resistance to metronidazole, clarithromycin, amoxicillin, tetracycline, and furazolidone in Brazil
    • Mendonça S, Ecclissato C, Sartori MS, Godoy APO, Guerzoni RA, Degger M, Pedrazzoli JJ. Prevalence of Helicobacter pylori resistance to metronidazole, clarithromycin, amoxicillin, tetracycline, and furazolidone in Brazil. Helicobacter. 2000;5:79-83.
    • (2000) Helicobacter , vol.5 , pp. 79-83
    • Mendonça, S.1    Ecclissato, C.2    Sartori, M.S.3    Godoy, A.P.O.4    Guerzoni, R.A.5    Degger, M.6    Pedrazzoli, J.J.7
  • 39
    • 0035135354 scopus 로고    scopus 로고
    • Nogueira C, Figueiredo C, Carneiro F, Gomes AT, Barreira R, Figueira P, Salgado C, Belo L, Peixoto A, Bravo JC, Bravo LE, Realpe JL, Plaisier AP, Quint WG, Ruiz B, Correa P, van Doorn LJ. Helicobacter pylori genotypes may determine gastric histopathology. Am J Pathol. 2001;158:647-54.2001;54.
    • Nogueira C, Figueiredo C, Carneiro F, Gomes AT, Barreira R, Figueira P, Salgado C, Belo L, Peixoto A, Bravo JC, Bravo LE, Realpe JL, Plaisier AP, Quint WG, Ruiz B, Correa P, van Doorn LJ. Helicobacter pylori genotypes may determine gastric histopathology. Am J Pathol. 2001;158:647-54.2001;54.
  • 40
    • 0033584434 scopus 로고    scopus 로고
    • Helicobacter pylori vacuolating cytotoxin (VacA) disorganizes the cytoskeletal architecture of gastric epithelial cells
    • Pai R, Cover TL, Tarnawski AS. Helicobacter pylori vacuolating cytotoxin (VacA) disorganizes the cytoskeletal architecture of gastric epithelial cells. Biochem Biophys Res Commun. 1999;262:245-50.
    • (1999) Biochem Biophys Res Commun , vol.262 , pp. 245-250
    • Pai, R.1    Cover, T.L.2    Tarnawski, A.S.3
  • 41
    • 0030951122 scopus 로고    scopus 로고
    • seroprevalence of CagA-positive strains among Helicobacter pylori-infected, healthy young adults
    • Parsonnet J, Replogle M, Yang S, Hiatt R. seroprevalence of CagA-positive strains among Helicobacter pylori-infected, healthy young adults. J Infect Dis. 1997;175:1240-2.
    • (1997) J Infect Dis , vol.175 , pp. 1240-1242
    • Parsonnet, J.1    Replogle, M.2    Yang, S.3    Hiatt, R.4
  • 43
    • 0035096391 scopus 로고    scopus 로고
    • Genetic diversity in the Helicobacter pylori cag pathogenicity island and effect on expression of anti-CagA serum antibody in UK patients with dyspepsia
    • Peters TM, Owen RJ, Slater E, Varea R, Teare EL, Saverymuttu S. Genetic diversity in the Helicobacter pylori cag pathogenicity island and effect on expression of anti-CagA serum antibody in UK patients with dyspepsia. J Clin Pathol. 2001;54:219-23.
    • (2001) J Clin Pathol , vol.54 , pp. 219-223
    • Peters, T.M.1    Owen, R.J.2    Slater, E.3    Varea, R.4    Teare, E.L.5    Saverymuttu, S.6
  • 44
    • 0023475048 scopus 로고
    • Indicator medium for isolation of Campylobacter pylori
    • Queiroz DMM, Mendes EN, Rocha GA. Indicator medium for isolation of Campylobacter pylori. J Clin Microbiol. 1987;25:2378-9.
    • (1987) J Clin Microbiol , vol.25 , pp. 2378-2379
    • Queiroz, D.M.M.1    Mendes, E.N.2    Rocha, G.A.3
  • 48
    • 0031594103 scopus 로고    scopus 로고
    • Diversity of Helicobacter pylori vacA and cagA genes and relationship to VacA and CagA protein expression, cytotoxin production, and associated diseases
    • Rudi J, Kolb C, Maiwald M, Kuck D, Sieg A, Galle PR, Stremmel W. Diversity of Helicobacter pylori vacA and cagA genes and relationship to VacA and CagA protein expression, cytotoxin production, and associated diseases. J Clin Microbiol. 1998;36:944-8.
    • (1998) J Clin Microbiol , vol.36 , pp. 944-948
    • Rudi, J.1    Kolb, C.2    Maiwald, M.3    Kuck, D.4    Sieg, A.5    Galle, P.R.6    Stremmel, W.7
  • 49
    • 0001442557 scopus 로고
    • Genetic analysis of amplified DNA with immobilized sequence-specific oligonucleotide probes
    • Saiki RK, Walsh PS, Levenson CH, Erlich HA. Genetic analysis of amplified DNA with immobilized sequence-specific oligonucleotide probes. Proc Natl Acad U S A. 1989;86:6230-4.
    • (1989) Proc Natl Acad U S A , vol.86 , pp. 6230-6234
    • Saiki, R.K.1    Walsh, P.S.2    Levenson, C.H.3    Erlich, H.A.4
  • 51
    • 0035795998 scopus 로고    scopus 로고
    • Helicobacter pylori and symptomatic relapse of gastro-oesophageal reflux disease: A randomised controlled trial
    • Schwizer W, Thumshirn M, Dent J, Guldenschuh I, Menne D, Cathomas G, Fried M. Helicobacter pylori and symptomatic relapse of gastro-oesophageal reflux disease: a randomised controlled trial. Lancet. 2001;357:1738-42.
    • (2001) Lancet , vol.357 , pp. 1738-1742
    • Schwizer, W.1    Thumshirn, M.2    Dent, J.3    Guldenschuh, I.4    Menne, D.5    Cathomas, G.6    Fried, M.7
  • 52
    • 0030034805 scopus 로고    scopus 로고
    • Helicobacter pylori attachment to gastric cells induces cytoskeletal rearrangements and tyrosine phosphorylation of host cell proteins
    • Segal ED, Falkow S, Tompkins LS. Helicobacter pylori attachment to gastric cells induces cytoskeletal rearrangements and tyrosine phosphorylation of host cell proteins. Proc Natl Acad U S A. 1996;93:1259-64.
    • (1996) Proc Natl Acad U S A , vol.93 , pp. 1259-1264
    • Segal, E.D.1    Falkow, S.2    Tompkins, L.S.3
  • 54
    • 0027230726 scopus 로고
    • Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: Evidence of linkage to cytotoxin production
    • Tummuru MK, Cover TL, Blaser MJ. Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: evidence of linkage to cytotoxin production. Infect Immun. 1993;61:1799-809.
    • (1993) Infect Immun , vol.61 , pp. 1799-1809
    • Tummuru, M.K.1    Cover, T.L.2    Blaser, M.J.3
  • 58
    • 0032253792 scopus 로고    scopus 로고
    • Relationship of vacA genotypes of Helicobacter pylori to cagA status, cytotoxin production, and clinical outcome
    • Yamaoka Y, Kodama T, Kita M, Imanishi J, Kashima K, Graham DY. Relationship of vacA genotypes of Helicobacter pylori to cagA status, cytotoxin production, and clinical outcome. Helicobacter. 1998;3:241-53.
    • (1998) Helicobacter , vol.3 , pp. 241-253
    • Yamaoka, Y.1    Kodama, T.2    Kita, M.3    Imanishi, J.4    Kashima, K.5    Graham, D.Y.6
  • 59
    • 0032587923 scopus 로고    scopus 로고
    • Relationship between Helicobacter pylori iceA, cagA, and vacA status and clinical outcome: Studies in four different countries
    • Yamaoka Y, Kodama T, Gutierrez O, Kim JG, Kashima K, Graham DY. Relationship between Helicobacter pylori iceA, cagA, and vacA status and clinical outcome: studies in four different countries. J Clin Microbiol. 1999;37:2274-9.
    • (1999) J Clin Microbiol , vol.37 , pp. 2274-2279
    • Yamaoka, Y.1    Kodama, T.2    Gutierrez, O.3    Kim, J.G.4    Kashima, K.5    Graham, D.Y.6
  • 60
    • 0031914577 scopus 로고    scopus 로고
    • Clinical and histological associations of cagA and vacA genotypes in Helicobacter pylori gastritis
    • Warburton VJ, Everett S, Mapstone NP, Axon AT, Hawkey P, Dixon MF. Clinical and histological associations of cagA and vacA genotypes in Helicobacter pylori gastritis. J Clin Pathol. 1998;51:55-61.
    • (1998) J Clin Pathol , vol.51 , pp. 55-61
    • Warburton, V.J.1    Everett, S.2    Mapstone, N.P.3    Axon, A.T.4    Hawkey, P.5    Dixon, M.F.6
  • 61
    • 1642431978 scopus 로고    scopus 로고
    • Helicobacter pylori vacuolating cytotoxin enters cells, localizes to the mitochondria, and induces mitochondrial membrane permeability changes correlated to toxin channel activity
    • Willhite DC, Blanke ER. Helicobacter pylori vacuolating cytotoxin enters cells, localizes to the mitochondria, and induces mitochondrial membrane permeability changes correlated to toxin channel activity. Cell Microbiol. 2004;6:143-54.
    • (2004) Cell Microbiol , vol.6 , pp. 143-154
    • Willhite, D.C.1    Blanke, E.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.