메뉴 건너뛰기




Volumn 34, Issue 11, 2007, Pages 4504-4513

Radioimmunotherapy with radioactive nanoparticles: First results of dosimetry for vascularized and necrosed solid tumors

Author keywords

Dosimetry; Monte Carlo; Nanomedicine; Radioimmunotherapy; Tumor model

Indexed keywords

CELL DEATH; DOSIMETRY; MEDICAL NANOTECHNOLOGY; MONOCLONAL ANTIBODIES; MONTE CARLO METHODS; NANOPARTICLES; RADIOACTIVITY; RADIOISOTOPES; RADIOTHERAPY;

EID: 35648966507     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.2791038     Document Type: Article
Times cited : (17)

References (67)
  • 1
    • 0036255688 scopus 로고    scopus 로고
    • Targeted therapy of cancer with radiolabeled antibodies
    • D. M. Goldenberg, " Targeted therapy of cancer with radiolabeled antibodies., " J. Nucl. Med. 43, 693-713 (2002).
    • (2002) J. Nucl. Med. , vol.43 , pp. 693-713
    • Goldenberg, D.M.1
  • 2
    • 33846549106 scopus 로고    scopus 로고
    • Advances in cancer therapy with radiolabeled monoclonal antibodies
    • D. M. Goldenberg and R. M. Sharkey, " Advances in cancer therapy with radiolabeled monoclonal antibodies., " Q. J. Nucl. Med. Mol. Imaging 50, 248-264 (2006).
    • (2006) Q. J. Nucl. Med. Mol. Imaging , vol.50 , pp. 248-264
    • Goldenberg, D.M.1    Sharkey, R.M.2
  • 3
    • 0037350545 scopus 로고    scopus 로고
    • Immunotherapy: Past, present and future
    • T. A. Waldmann, " Immunotherapy: Past, present and future., " Nat. Med. 9, 269-277 (2003).
    • (2003) Nat. Med. , vol.9 , pp. 269-277
    • Waldmann, T.A.1
  • 4
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • P. Carmeliet, " Angiogenesis in health and disease., " Nat. Med. 9, 653-660 (2003).
    • (2003) Nat. Med. , vol.9 , pp. 653-660
    • Carmeliet, P.1
  • 5
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • J. Folkman, " Angiogenesis in cancer, vascular, rheumatoid and other disease., " Nat. Med. 1, 27-31 (1995).
    • (1995) Nat. Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 7
    • 14544270602 scopus 로고    scopus 로고
    • Recent advances in pretargeted radio-immunotherapy
    • A. Gruaz-Guyon, O. Raguin, and J. Barbet, " Recent advances in pretargeted radio-immunotherapy., " Curr. Med. Chem. 12, 319-338 (2005).
    • (2005) Curr. Med. Chem. , vol.12 , pp. 319-338
    • Gruaz-Guyon, A.1    Raguin, O.2    Barbet, J.3
  • 9
    • 0002631056 scopus 로고    scopus 로고
    • Radioimmunotherapy for patients with relapsed B-cell non-Hodgkin lymphoma
    • T. E. Witzig, " Radioimmunotherapy for patients with relapsed B-cell non-Hodgkin lymphoma., " Cancer Chemother. Pharmacol. 48, 91S-95S (2001).
    • (2001) Cancer Chemother. Pharmacol. , vol.48
    • Witzig, T.E.1
  • 10
    • 0034570689 scopus 로고    scopus 로고
    • Antibody-targeted immunotherapy for treatment of non-Hodgkin's lymphoma
    • C. A. White, J. R. Berlfein, and A. J. Grillo-Lopez, " Antibody-targeted immunotherapy for treatment of non-Hodgkin's lymphoma., " Curr. Pharm. Biotechnol. 1, 303-312 (2000).
    • (2000) Curr. Pharm. Biotechnol. , vol.1 , pp. 303-312
    • White, C.A.1    Berlfein, J.R.2    Grillo-Lopez, A.J.3
  • 11
    • 0034970692 scopus 로고    scopus 로고
    • The role of radiolabeled antibodies in the treatment of non-Hodgkin's lymphoma: The coming of age of radioimmunotherapy
    • D. M. Goldenberg, " The role of radiolabeled antibodies in the treatment of non-Hodgkin's lymphoma: the coming of age of radioimmunotherapy., " Crit. Rev. Oncol. Hematol. 39, 195-201 (2001).
    • (2001) Crit. Rev. Oncol. Hematol. , vol.39 , pp. 195-201
    • Goldenberg, D.M.1
  • 13
    • 24144486232 scopus 로고    scopus 로고
    • Targeted cancer therapy using radiolabeled monoclonal antibodies
    • W. A. Bethge and B. M. Sandmaier, " Targeted cancer therapy using radiolabeled monoclonal antibodies., " Technol. Cancer Res. Treat. 4, 393-405 (2005).
    • (2005) Technol. Cancer Res. Treat. , vol.4 , pp. 393-405
    • Bethge, W.A.1    Sandmaier, B.M.2
  • 15
    • 14844343723 scopus 로고    scopus 로고
    • Perspectives on cancer therapy with radiolabeled monoclonal antibodies
    • R. M. Sharkey and D. M. Goldenberg, " Perspectives on cancer therapy with radiolabeled monoclonal antibodies., " J. Nuc. Med. Treat. 46, 115S-127S (2005).
    • (2005) J. Nuc. Med. Treat. , vol.46
    • Sharkey, R.M.1    Goldenberg, D.M.2
  • 16
    • 0037615120 scopus 로고    scopus 로고
    • Advancing role of radiolabeled antibodies in the therapy of cancer
    • D. M. Goldenberg, " Advancing role of radiolabeled antibodies in the therapy of cancer., " Cancer Immunol. Immunother 52, 281-296 (2003).
    • (2003) Cancer Immunol. Immunother , vol.52 , pp. 281-296
    • Goldenberg, D.M.1
  • 17
    • 2442421780 scopus 로고    scopus 로고
    • Structure and magnetic properties of FePt alloy cluster-assembled film
    • D. L. Peng, T. Hihara, and K. Sumiyama, " Structure and magnetic properties of FePt alloy cluster-assembled film., " J. Magn. Magn. Mater. 277, 201-208 (2004).
    • (2004) J. Magn. Magn. Mater. , vol.277 , pp. 201-208
    • Peng, D.L.1    Hihara, T.2    Sumiyama, K.3
  • 19
    • 0033752307 scopus 로고    scopus 로고
    • Grazing-incidence small-angle x-ray scattering applied to the characterization of aggregates in surface regions
    • A. Naudon, D. Babonneau, D. Thiaudìre, and S. Lequien, " Grazing-incidence small-angle x-ray scattering applied to the characterization of aggregates in surface regions., " Physica B 283, 69-74 (2000).
    • (2000) Physica B , vol.283 , pp. 69-74
    • Naudon, A.1    Babonneau, D.2    Thiaudìre, D.3    Lequien, S.4
  • 20
    • 0029214768 scopus 로고
    • Nanoparticles and filled nanocapsules
    • Y. Saito, " Nanoparticles and filled nanocapsules., " Carbon 33, 979-988 (1995).
    • (1995) Carbon , vol.33 , pp. 979-988
    • Saito, Y.1
  • 21
    • 0034996764 scopus 로고    scopus 로고
    • Long-circulating and target-specific nanoparticles: Theory to practice
    • S. M. Moghimi, A. C. Hunter, and J. C. Murray, " Long-circulating and target-specific nanoparticles: Theory to practice., " Pharmacol. Rev. 53, 283-318 (2001).
    • (2001) Pharmacol. Rev. , vol.53 , pp. 283-318
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 22
    • 0141927263 scopus 로고    scopus 로고
    • Stealth liposomes and long circulating nanoparticles: Critical issues in pharmacokinetics, opsonization, and protein-binding properties
    • S. M. Moghimi and J. Szebeni, " Stealth liposomes and long circulating nanoparticles: Critical issues in pharmacokinetics, opsonization, and protein-binding properties., " Prog. Lipid Res. 42, 463-478 (2003).
    • (2003) Prog. Lipid Res. , vol.42 , pp. 463-478
    • Moghimi, S.M.1    Szebeni, J.2
  • 23
    • 0035045942 scopus 로고    scopus 로고
    • Recognition by macrophages and liver cells of opsonized phospholipid vesicles and phospholipid headgroups
    • S. M. Moghimi and A. C. Hunter, " Recognition by macrophages and liver cells of opsonized phospholipid vesicles and phospholipid headgroups., " Pharm. Res. 18, 1-8 (2001).
    • (2001) Pharm. Res. , vol.18 , pp. 1-8
    • Moghimi, S.M.1    Hunter, A.C.2
  • 24
    • 28844488494 scopus 로고    scopus 로고
    • Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles
    • E. D. Owens, III and N. A. Peppas, " Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles., " Int. J. Pharm. 307, 93-102 (2006).
    • (2006) Int. J. Pharm. , vol.307 , pp. 93-102
    • Owens III, E.D.1    Peppas, N.A.2
  • 25
    • 14644396096 scopus 로고    scopus 로고
    • Nanomedicine: Current status and future prospect
    • S. M. Moghimi, A. C. Hunter, and J. C. Murray, " Nanomedicine: Current status and future prospect., " FASEB J. 19, 311-330 (2005).
    • (2005) FASEB J. , vol.19 , pp. 311-330
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 26
    • 0343191443 scopus 로고    scopus 로고
    • Stealth corona-core nanoparticles surface modified by polyethylene glycol (PEG): Influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption
    • R. Gref, M. Luck, P. Quellec, M. Marchand, E. Dellacherie, S. Harnish, T. Blunk, and R. H. Muller, " Stealth corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption., " Colloids Surf., B 18, 301-313 (2000).
    • (2000) Colloids Surf., B , vol.18 , pp. 301-313
    • Gref, R.1    Luck, M.2    Quellec, P.3    Marchand, M.4    Dellacherie, E.5    Harnish, S.6    Blunk, T.7    Muller, R.H.8
  • 27
    • 16844384331 scopus 로고    scopus 로고
    • A polymeric nanoparticle consisting of mPEG-PLA-Toco and PLMA-COONa as a drug carrier: Improvements in cellular uptake and biodistribution
    • Y. Yi, J. H. Kim, H.-W. Kang, H. S. Oh, S. W. Kim, and M. H. Seo, " A polymeric nanoparticle consisting of mPEG-PLA-Toco and PLMA-COONa as a drug carrier: improvements in cellular uptake and biodistribution., " Pharm. Res. 22, 200-208 (2005).
    • (2005) Pharm. Res. , vol.22 , pp. 200-208
    • Yi, Y.1    Kim, J.H.2    Kang, H.-W.3    Oh, H.S.4    Kim, S.W.5    Seo, M.H.6
  • 28
    • 35648976223 scopus 로고    scopus 로고
    • Functionalisation of magnetic nanoparticles for applications in biomedicine
    • C. C. Berry and A. S. G. Curtis, " Functionalisation of magnetic nanoparticles for applications in biomedicine., " J. Leukoc Biol. 78, 585-594 (2005).
    • (2005) J. Leukoc Biol. , vol.78 , pp. 585-594
    • Berry, C.C.1    Curtis, A.S.G.2
  • 29
    • 24744447202 scopus 로고    scopus 로고
    • Nanotechnology for the biologist
    • S. E. McNeil, " Nanotechnology for the biologist., " J. Leukoc Biol. 78, 585-594 (2005).
    • (2005) J. Leukoc Biol. , vol.78 , pp. 585-594
    • McNeil, S.E.1
  • 30
    • 23744471772 scopus 로고    scopus 로고
    • Drug targeting with nano-sized carrier systems
    • M. Yokoyama, " Drug targeting with nano-sized carrier systems., " J. Artif. Organs 8, 77-84 (2005).
    • (2005) J. Artif. Organs , vol.8 , pp. 77-84
    • Yokoyama, M.1
  • 32
    • 0037225979 scopus 로고    scopus 로고
    • Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots
    • X. Wu, H. Liu, K. N. Haley, J. A. Treadway, J. P. Larson, N. Ge, F. Peale, and M. P. Bruchez, " Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots., " Nat. Biotechnol. 21, 41-46 (2003).
    • (2003) Nat. Biotechnol. , vol.21 , pp. 41-46
    • Wu, X.1    Liu, H.2    Haley, K.N.3    Treadway, J.A.4    Larson, J.P.5    Ge, N.6    Peale, F.7    Bruchez, M.P.8
  • 33
    • 3543022686 scopus 로고    scopus 로고
    • In vivo cancer targeting and imaging with semiconductor quantum dots
    • X. Gao, Y. Cui, R. M. Levenson, L. W. K. Chung, and S. Nie, " In vivo cancer targeting and imaging with semiconductor quantum dots., " Nat. Biotechnol. 22, 969-976 (2004).
    • (2004) Nat. Biotechnol. , vol.22 , pp. 969-976
    • Gao, X.1    Cui, Y.2    Levenson, R.M.3    Chung, L.W.K.4    Nie, S.5
  • 34
    • 34447258534 scopus 로고    scopus 로고
    • Quantum dots and multifunctional nanoparticles: New contrast agents for tumor imaging
    • M. N. Rhyner, A. M. Smith, X. Gao, H. Mao, L. Yang, and S. Nie, " Quantum dots and multifunctional nanoparticles: new contrast agents for tumor imaging., " Nanomedicine 1, 209-217 (2006).
    • (2006) Nanomedicine , vol.1 , pp. 209-217
    • Rhyner, M.N.1    Smith, A.M.2    Gao, X.3    Mao, H.4    Yang, L.5    Nie, S.6
  • 35
    • 0021844359 scopus 로고
    • Magnetic separation techniques: Their application to medicine
    • J. T. Kemshead and J. Ugelstad, " Magnetic separation techniques: their application to medicine., " Mol. Cell. Biochem. 67, 11-18 (1985).
    • (1985) Mol. Cell. Biochem. , vol.67 , pp. 11-18
    • Kemshead, J.T.1    Ugelstad, J.2
  • 36
    • 3543114327 scopus 로고    scopus 로고
    • A relevant immunomagnetic assay to detect and characterize epithelial cell adhesion molecule-positive cells in bone marrow from patients with breast carcinoma: Immunomagnetic purification of micrometastases
    • V. Choesmel, P. Anract, H. Hoifodt, J. P. Thiery, and N. Blin, " A relevant immunomagnetic assay to detect and characterize epithelial cell adhesion molecule-positive cells in bone marrow from patients with breast carcinoma: immunomagnetic purification of micrometastases., " Cancer 101, 693-703 (2004).
    • (2004) Cancer , vol.101 , pp. 693-703
    • Choesmel, V.1    Anract, P.2    Hoifodt, H.3    Thiery, J.P.4    Blin, N.5
  • 37
    • 18144410597 scopus 로고    scopus 로고
    • Immunotargeted nanoshells for integreted cancer imaging and therapy
    • C. Loo, A. Lowery, N. Halas, J. West, and R. Drezek, " Immunotargeted nanoshells for integreted cancer imaging and therapy., " Nano Lett. 5, 709-711 (2005).
    • (2005) Nano Lett. , vol.5 , pp. 709-711
    • Loo, C.1    Lowery, A.2    Halas, N.3    West, J.4    Drezek, R.5
  • 39
    • 12444304458 scopus 로고    scopus 로고
    • Near-IR luminescence of monolayer-protected metal clusters
    • G. Wang, T. Huang, R. W. Murray, L. Menard, and R. G. Nuzzo, " Near-IR luminescence of monolayer-protected metal clusters., " J. Am. Chem. Soc. 127, 812-813 (2005).
    • (2005) J. Am. Chem. Soc. , vol.127 , pp. 812-813
    • Wang, G.1    Huang, T.2    Murray, R.W.3    Menard, L.4    Nuzzo, R.G.5
  • 40
    • 37149001634 scopus 로고    scopus 로고
    • Determination of biological vector characteristics and nanoparticle dimensions for radioimmunotherapy with radioactive nanoparticles
    • V. E. Nuttens, A.-C. Wera, V. Bouchat, and S. Lucas, " Determination of biological vector characteristics and nanoparticle dimensions for radioimmunotherapy with radioactive nanoparticles., " Appl. Radiat. Isot. (accepted).
    • Appl. Radiat. Isot.
    • Nuttens, V.E.1    Wera, A.-C.2    Bouchat, V.3    Lucas, S.4
  • 41
    • 0033205573 scopus 로고    scopus 로고
    • The role of vascular phase in solid tumor growth: A historical review
    • D. Ribatti, A. Vacca, and F. Dammacco, " The role of vascular phase in solid tumor growth: A historical review., " Neoplasia 1, 293-302 (1999).
    • (1999) Neoplasia , vol.1 , pp. 293-302
    • Ribatti, D.1    Vacca, A.2    Dammacco, F.3
  • 42
    • 0015008620 scopus 로고
    • Isolation of a tumor factor responsible or angiogenesis
    • J. Folkman, E. Merler, C. Abernathy, and G. Williams, " Isolation of a tumor factor responsible or angiogenesis., " J. Exp. Med. 133, 275-288 (1971).
    • (1971) J. Exp. Med. , vol.133 , pp. 275-288
    • Folkman, J.1    Merler, E.2    Abernathy, C.3    Williams, G.4
  • 43
    • 0024281372 scopus 로고
    • Cell and environment interactions in tumor microregions: The multicell spheroid model
    • R. M. Sutherland, " Cell and environment interactions in tumor microregions: The multicell spheroid model., " Science 240, 177-184 (1988).
    • (1988) Science , vol.240 , pp. 177-184
    • Sutherland, R.M.1
  • 44
  • 45
    • 0024565290 scopus 로고
    • Macroscopic dosimetry for radioimmuno-therapy: Nonuniform activity distributions in solid tumors
    • R. W. Howell, D. V. Rao, and K. S. R. Sastry, " Macroscopic dosimetry for radioimmuno-therapy: Nonuniform activity distributions in solid tumors., " Med. Phys. 16, 66-74 (1989).
    • (1989) Med. Phys. , vol.16 , pp. 66-74
    • Howell, R.W.1    Rao, D.V.2    Sastry, K.S.R.3
  • 46
    • 0029789267 scopus 로고    scopus 로고
    • Absorbed dose distribution of the auger emitters 67Ga and 125I and the Β -emitters 67Cu, 90Y, 131I, and 186Re as a function of tumor size, uptake, and intracellular distributin
    • E. B. Van Dieren, M. A. B. D. Plaizier, A. Van Lingen, J. C. Roos, G. W. Barendsen, and G. J. J. Teule, " Absorbed dose distribution of the auger emitters 67Ga and 125I and the Β -emitters 67Cu, 90Y, 131I, and 186Re as a function of tumor size, uptake, and intracellular distributin., " Int. J. Radiat. Oncol., Biol., Phys. 36, 197-204 (1996).
    • (1996) Int. J. Radiat. Oncol., Biol., Phys. , vol.36 , pp. 197-204
    • Van Dieren, E.B.1    Plaizier, M.A.B.D.2    Van Lingen, A.3    Roos, J.C.4    Barendsen, G.W.5    Teule, G.J.J.6
  • 48
    • 33750379802 scopus 로고    scopus 로고
    • Homopolyvalent antibody-antigen interaction kinetic studies with use of a dual-polarization interferometric biosensor
    • S. Lin, C.-K. Lee, Y.-H. Lin, S.-Y. Lee, B.-C. Sheu, J.-C. Tsai, and S.-M. Hsu, " Homopolyvalent antibody-antigen interaction kinetic studies with use of a dual-polarization interferometric biosensor., " Biosens. Bioelectron. 22, 715-721 (2006).
    • (2006) Biosens. Bioelectron. , vol.22 , pp. 715-721
    • Lin, S.1    Lee, C.-K.2    Lin, Y.-H.3    Lee, S.-Y.4    Sheu, B.-C.5    Tsai, J.-C.6    Hsu, S.-M.7
  • 49
    • 0034054531 scopus 로고    scopus 로고
    • High-resolution imaging of antibodies by tapping-mode atomic force microscopy: Attractive and repulsive tip-sample interaction regimes
    • A. S. Paulo and R. Garcia, " High-resolution imaging of antibodies by tapping-mode atomic force microscopy: attractive and repulsive tip-sample interaction regimes., " Biophys. J. 78, 1599-1605 (2006).
    • (2006) Biophys. J. , vol.78 , pp. 1599-1605
    • Paulo, A.S.1    Garcia, R.2
  • 50
  • 51
    • 0025981665 scopus 로고
    • Structure of solid tumors and their vasculature: Implications for therapy with monoclonal antibodies
    • H. F. Dvorak, J. A. Nagy, and A. M. Dvorak, " Structure of solid tumors and their vasculature: Implications for therapy with monoclonal antibodies., " Cancer Cells 3, 77-85 (1991).
    • (1991) Cancer Cells , vol.3 , pp. 77-85
    • Dvorak, H.F.1    Nagy, J.A.2    Dvorak, A.M.3
  • 52
    • 0036067866 scopus 로고    scopus 로고
    • Vascularization of cutaneous melanoma involves vessel co-option and has clinical significance
    • B. Döme, S. Paku, B. Somlai, and J. Timar, " Vascularization of cutaneous melanoma involves vessel co-option and has clinical significance., " J. Pathol. 197, 355-362 (2002).
    • (2002) J. Pathol. , vol.197 , pp. 355-362
    • Döme, B.1    Paku, S.2    Somlai, B.3    Timar, J.4
  • 53
    • 0032868402 scopus 로고    scopus 로고
    • Relation between vascularization and proliferation in invasive breast cancer
    • J. A. M. Belin, P. J. van Diest, and J. P. A. Baak, " Relation between vascularization and proliferation in invasive breast cancer., " J. Pathol. 189, 309-318 (1999).
    • (1999) J. Pathol. , vol.189 , pp. 309-318
    • Belin, J.A.M.1    Van Diest, P.J.2    Baak, J.P.A.3
  • 55
    • 33144475089 scopus 로고    scopus 로고
    • Flow correlated percolation during vascular remodeling in growing tumors
    • D.-S. Lee, H. Rieger, and K. Bartha, " Flow correlated percolation during vascular remodeling in growing tumors., " Phys. Rev. Lett. 96, 058104 (2006).
    • (2006) Phys. Rev. Lett. , vol.96 , pp. 058104
    • Lee, D.-S.1    Rieger, H.2    Bartha, K.3
  • 56
    • 33746260079 scopus 로고    scopus 로고
    • Vascular network remodeling via vessel cooption, regression and growth in tumors
    • K. Bartha and H. Rieger, " Vascular network remodeling via vessel cooption, regression and growth in tumors., " J. Theor. Biol. 241, 903-918 (2006).
    • (2006) J. Theor. Biol. , vol.241 , pp. 903-918
    • Bartha, K.1    Rieger, H.2
  • 57
    • 0025073214 scopus 로고
    • Nonuniformity of tumor dose in radioimmunotherapy
    • J. L. Humm and L. M. Cobb, " Nonuniformity of tumor dose in radioimmunotherapy., " J. Nucl. Med. 31, 75-83 (1990).
    • (1990) J. Nucl. Med. , vol.31 , pp. 75-83
    • Humm, J.L.1    Cobb, L.M.2
  • 59
    • 0036798699 scopus 로고    scopus 로고
    • Parameter dependence of the MCNP electron transport in determining dose distributions
    • N. Reynaert, H. Palmans, H. Thierens, and R. Jeraj, " Parameter dependence of the MCNP electron transport in determining dose distributions., " Med. Phys. 29, 2446-2454 (2002).
    • (2002) Med. Phys. , vol.29 , pp. 2446-2454
    • Reynaert, N.1    Palmans, H.2    Thierens, H.3    Jeraj, R.4
  • 60
    • 0037035394 scopus 로고    scopus 로고
    • A comparison of MCNP4C electron transport with ITS 3.0 and experiment at incident energies between 100 keV and 20 MeV: Influence of voxel size, substeps and energy indexing algorithm
    • D. R. Schaart, J. Th.M. Jansen, J. Zoetelief, and P. F. A. de Leege, " A comparison of MCNP4C electron transport with ITS 3.0 and experiment at incident energies between 100 keV and 20 MeV: influence of voxel size, substeps and energy indexing algorithm., " Phys. Med. Biol. 47, 1459-1484 (2002).
    • (2002) Phys. Med. Biol. , vol.47 , pp. 1459-1484
    • Schaart, D.R.1    Th.m., J.J.2    Zoetelief, J.3    De Leege, P.F.A.4
  • 61
    • 0141568194 scopus 로고    scopus 로고
    • Targeting endothelial growth with monoclonal antibodies against Tie-1 kinase in mouse models
    • P. Karnami and K. Kairemo, " Targeting endothelial growth with monoclonal antibodies against Tie-1 kinase in mouse models., " Clin. Cancer Res. 9, 3821s-3826s (2003).
    • (2003) Clin. Cancer Res. , vol.9
    • Karnami, P.1    Kairemo, K.2
  • 62
    • 0029999273 scopus 로고    scopus 로고
    • In vivo modulators of antibody kinetics
    • A. Jekunen, K. Kairemo, and P. Karnami, " In vivo modulators of antibody kinetics., " Acta Oncol. 35, 267-271 (1996).
    • (1996) Acta Oncol. , vol.35 , pp. 267-271
    • Jekunen, A.1    Kairemo, K.2    Karnami, P.3
  • 66
    • 7144250528 scopus 로고    scopus 로고
    • Feasibility and pharmacokinetic study of a chimeric anti-CD20 monoclonal antibody (IDEC-C2B8, rituximab) in relapsed B-cell lymphoma
    • K. Tobinai, Y. Kobayashi, and M. Narabayashi, " Feasibility and pharmacokinetic study of a chimeric anti-CD20 monoclonal antibody (IDEC-C2B8, rituximab) in relapsed B-cell lymphoma., " Ann. Oncol. 9, 527-534 (1998).
    • (1998) Ann. Oncol. , vol.9 , pp. 527-534
    • Tobinai, K.1    Kobayashi, Y.2    Narabayashi, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.