A novel functional approach toward identifying definitive drug targets

Current Medicinal Chemistry

Volumn 14, Issue 22, 2007, Pages 2380-2392

  Dey, Ranadhir ^a   Khan, Srijit ^a   Saha, Bhaskar ^a  

^a NATIONAL CENTRE FOR CELL SCIENCE   (India)

Author keywords

Drug development strategy; Drug resistance; Drug target identification; Genomics and proteomics; Host parasite interaction; Immunomodulation; Immunotherapy; Leishmania infection

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ADENOVIRUS VECTOR; AMPHOTERICIN B; AMPRENAVIR; ANISOMYCIN; ANTIBIOTIC AGENT; ANTIMONY GLUCONATE; ANTIRETROVIRUS AGENT; CEP 1347; CYCLOSPORIN; GENE PRODUCT; HERPESVIRUS VECTOR; MILTEFOSINE; N (2 METHYLAMINOETHYL) 5 ISOQUINOLINESULFONAMIDE; NELFINAVIR; PARVOVIRUS VECTOR; PENTAMIDINE; PROTEIN KINASE; PROTEIN KINASE C INHIBITOR; PROTEIN KINASE INHIBITOR; PROTEINASE; PROTEINASE INHIBITOR; RAPAMYCIN; RETROVIRUS VECTOR; SIALIDASE; SMALL INTERFERING RNA; STAUROSPORINE; UNINDEXED DRUG; ZANAMIVIR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; CELL SURVIVAL; COMBINATORIAL CHEMISTRY; DRUG RESEARCH; DRUG RESISTANCE; DRUG TARGETING; FUNCTIONAL GENOMICS; GASTROINTESTINAL DISEASE; GENE ACTIVATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE SILENCING; GENE THERAPY; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HIGH THROUGHPUT SCREENING; HOST PATHOGEN INTERACTION; HUMAN; HUMAN GENOME PROJECT; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOMODULATION; INFLUENZA; LEISHMANIA; LEISHMANIASIS; MEASLES VIRUS; METHODOLOGY; MICROARRAY ANALYSIS; MOLECULAR MECHANICS; PARAINFLUENZA VIRUS; PHARMACOGENOMICS; PROTEIN ANALYSIS; PROTEOMICS; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; RNA INTERFERENCE; ROBOTICS; SARS CORONAVIRUS; SERIAL ANALYSIS OF GENE EXPRESSION; SEVERE ACUTE RESPIRATORY SYNDROME; SIGNAL TRANSDUCTION; TRYPANOSOMA CRUZI; VIRAL GENE DELIVERY SYSTEM; X RAY CRYSTALLOGRAPHY;

CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; DRUG RESISTANCE; ENZYME ACTIVATORS; ENZYME INHIBITORS; GENOMICS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHARMACEUTICAL PREPARATIONS; PROTEOMICS; RNA, SMALL INTERFERING;

EID: 35448981511     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986707781745523     Document Type: Review

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