CD40 signaling is impaired in L. major-infected macrophages and is rescued by a p38MAPK activator establishing a host-protective memory T cell response

Journal of Experimental Medicine

Volumn 197, Issue 8, 2003, Pages 1037-1043

  Awasthi, Amit ^a   Mathur, Ramkumar ^a   Khan, Aslam ^a   Joshi, Bimba N ^a   Jain, Nitya ^a   Sawant, Sangeeta ^b   Boppana, Ramanamurthy ^a   Mitra, Debashis ^a   Saha, Bhaskar ^a  

^a NATIONAL CENTRE FOR CELL SCIENCE   (India)

^b UNIVERSITY OF PUNE   (India)

Author keywords

CD40 signaling; Immune evasion mechanism; Leishmaniasis; p38MAPK; T cell memory

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANISOMYCIN; CD40 ANTIGEN; CD40 LIGAND; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NITRIC OXIDE SYNTHASE; SYNAPTOPHYSIN;

AMASTIGOTE; ANIMAL CELL; ARTICLE; CROSS LINKING; HOST PATHOGEN INTERACTION; IMMUNE RESPONSE; LEISHMANIA MAJOR; MACROPHAGE; MALE; MEMORY CELL; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TH1 CELL;

ANIMALS; ANISOMYCIN; ANTIGENS, CD40; CELLS, CULTURED; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; IMIDAZOLES; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN SYNTHESIS INHIBITORS; PYRIDINES; SIGNAL TRANSDUCTION; TH1 CELLS;

EID: 0037460059     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20022033     Document Type: Article

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