High-affinity aptamers selectively inhibit human nonpancreatic secretory phospholipase A2 (hnps-PLA2)

Journal of Medicinal Chemistry

Volumn 41, Issue 6, 1998, Pages 778-786

  Bridonneau, Philippe ^a   Chang, Ying Fon ^a   O'Connell, Dan ^b   Gill, Stanley C ^b   Snyder, David W ^b   Johnson, Lea ^a   Goodson Jr , Theodore ^a   Herron, David K ^a   Parma, David H ^a  

^a GILEAD SCIENCES   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; BINDING PROTEIN; IMMUNOGLOBULIN G; LEUKOCYTE ELASTASE; OLIGONUCLEOTIDE; PHOSPHOLIPASE A2; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CONCENTRATION RESPONSE; ENZYME BINDING; ENZYME INHIBITION; GUINEA PIG; MALE; NONHUMAN; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DRUG DESIGN; ENZYME INHIBITORS; GENE LIBRARY; GUINEA PIGS; HUMANS; INDOLES; LUNG; MALE; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; PHOSPHOLIPASES A; PLEURA; RNA;

EID: 0032510316     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970579k     Document Type: Article

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