S-adenosylhomocysteine as a physiological modulator of Apo-1-mediated apoptosis

International Immunology

Volumn 8, Issue 7, 1996, Pages 1139-1147

  Ratter, Frank ^a   Germer, Matthias ^a   Fischbach, Thomas ^a   Schulze Osthoff, Klaus ^a   Peter, Marcus E ^a   Dröge, Wulf ^a   Krammer, Peter H ^a   Lehmann, Volker ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Adenosine; Anti APO 1 antibody; Arachidonic acid; Cell death; D,L homocysteine; DNA; Fragmentation

Indexed keywords

ADENOSINE; ANTIBODY; ARACHIDONIC ACID; DNA FRAGMENT; HOMOCYSTEINE; PHOSPHOLIPASE A2; PHOSPHOLIPID; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DEATH; CELL KILLING; CELL STRAIN L 929; CELL TYPE; CONTROLLED STUDY; METHYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION;

ADENOSINE; ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD95; APOPTOSIS; CYTOTOXICITY, IMMUNOLOGIC; L CELLS (CELL LINE); MICE; PHOSPHOLIPASES A; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE; TRANSFECTION;

EID: 0030018196     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/8.7.1139     Document Type: Article

References (41)

1. Trauth, B. C., Klas, C., Peters. A. M. J., Matzku, S., Möller, P., Falk, W., Debatin, K.-M. and Krammer, P. H. 1989. Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 245:301.
2. Yonehara, S., Ishii, A. and Yonehara, M. 1989. A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J. Exp. Med. 169:1747.
3. Itoh, N., Yonehara, S., Ishii, A., Yonehara, M., Mizushima, S.-l., Sameshima, M., Hase, A., Seto, Y. and Nagata, S. 1991. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66:233.
4. Oehm, A., Behrmann, I., Falk W., Pawlita, M., Maier, G., Klas, C., Li-Weber, M., Richards, S., Dhein, J., Trauth, B. C., Ponstingl, H. and Krammer, P. H. 1992, Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen, J. Biol. Chem. 267:10709.
5. Loetscher, H., Pan. Y. E., Lahm, H.-W., Gentz, R., Brockhaus, M., Tabuchi, H. and Lesslauer, W. 1990. Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor. Cell 61:351.
6. Schall, T. J., Lewis, M., Koller, K. J., Lee, A., Rice, G. l., Wong, G, H, W., Gatanaga, T., Granger, G. A. Lentz, R., Raab, H., Kohr, W. J. and Goeddel, D. V. 1990. Molecular cloning and expression of a receptor for human tumor necrosis factor. Cell 61:361.
7. Smith, C A., Davis, T., Anderson, D., Solam, L., Beckmann, M. P., Jerzy, R., Dower, S. K., Cosman, D. and Goodwin, R. G. 1990. A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. Science 248:1019.
8. Camerini, D., Walz, G., Loenen, W. A. M., Borst, J. and Seed, B. 1991. The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family. J. Immunol. 147:3165.
9. Dürkop, H., Latza. U., Hummel, M., Eitelbach, F., Seed, B. and Stein, H. 1992. Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease. Cell 68:421.
10. Stamenkovic, I., Clark, E. A. and Seed, B. 1989. A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. EMBO J. 8:1403.
11. Kwon, B S. and Weissman, S. M. 1989. cDNA sequences of two inducible T cell genes. Proc. Natl. Acad. Sci. USA 86:1963.
12. Beutler. B. and van Huffel, C. 1994. Unraveling function in the TNF ligand and receptor families (comment). Science 264:667.
13. Smith, C. A., Farrah, T. and Goodwin, R. G. 1994, The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell 76:959.
14. Suda, T., Takahashi.T.,Golstein,P. and Nagata, S. 1993. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75:1169.
15. Miyawaki, T., Uehara. T., Nibu, R., Tsuji, T., Yachie, A., Yonehara, S. and Taniguchi, N. 1992. Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J. Immunol. 149:3753.
16. Watanabe-Fukunaga, R., Brannan, C. I., Copeland, N. G., Jenkins, N. A. and Nagata N. 1992. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:314.
17. Dhein, J., Walczak, H., B̈umler, C., Debatin, K. M. and Krammer, P. H. 1995. Autocrine T-cell suicide mediated by APO-1 (Fas/ CD95). Nature 373: 438.
18. Brunner, T., Mogil, R. J., LaFace, D., Yoo, N. J., Mahboubl, A., Echeverri, J., Martin, J., Force, W R., Lynch, D. H., Ware, C. H. and Green, D. R. 1995. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 373:441.
19. Ju, S. T., Panka, D. J., Cui, H., Ettinger, R., EI-Khatib, M., Sherr, D. H. Stanger, B. Z. and Marshak-Rothstein, A. 1995. Fas (CD95) FasL interactions required for programmed cell death after T-cell activation Nature 373:444.
20. (2+)-independent T cell-mediated cytotoxicity. J. Exp. Med. 177:195.
21. Lowin, B., Hahne, M., Mattmann, C. and Tschopp, J. 1994. Cytolytic T cell cytotoxicity is mediated through perforin and Fas lytic pathways. Nature 370:650.
22. Raff, M. C. 1992. Social controls on cell survival and cell death. Nature 356:397.
23. Tartaglia, L. A., Ayres, T. M., Wong, G. H. W. and Goeddel, D. V. 1993. A novel domain within the 55 kd TNF receptor signals cell death. Cell 74:845.
24. Eischen, C. M., Dick, C. J. and Leibson, P. J. 1994. Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis. J. Immunol. 153.1947.
25. Sato, T., Irie, S., Kitada, S. and Reed, J. C. 1995. FAP-1: a protein tyrosine phosphatase that associates with Fas. 1995. Science 268:441.
26. Gulbins, E., Bissonnette, R., Mahboubi, A., Martin, S., Nishioka, W., Brunner, T., Baier, G., Baier-Bitterlich, G., Byrd, C., Lang, F., Kolesnick, R. and Altman, A. 1995. Fas-induced apoptosis is mediated via a ceramide-initiated Ras signaling pathway. Immunity 2:341.
27. Los, M., VandeCraen, M., Penning, L. C., Schenk, H., Westendorp, M., Bauerle, P. A., Dröge, W., Krammer, P. H., Fiers, W. and Schulze-Osthoff, K. 1995. Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature 375:81.
28. Schulze-Osthoff, K., Kramrner, P. H. and Dröe, W. 1994. Divergent signalling via APO-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death. EMBO J. 13:4587.
29. Luthman, H. and Magnusson, G. 1983. High efficiency polyoma DNA transfection with chloroquine treated cells. Nucleic Acids Res, 11:1295.
30. Sladowski, D., Steer, S. J., Clothier, R. H. and Balls, M. 1993. An improved MTT assay. J. Immunol. Methods 157:203.
31. Wyllie, A. H. and Morris, R. G. 1982 Hormone-induced cell death. Purification and properties of thymocytes undergoing apoptosis after glucocorticoid treatment. Am. J. Pathol. 109:78.
32. Riendeau, D., Guay, J., Weech, P. K., Laliberte, P., Yergey, J., Li, C., Desmarais, S., Perrier, H., Liu, S., Nicoll-Grifth, D. and Street, I. P. 1994. Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophorechallenged platelets. J. Biol. Chem. 269:15619.
33. Helland, S. and Ueland, P. M. 1982. Inactivation of S-adenosylhomocysteine hydrolase by 9-β-D-arabinofuranosyladenine in intact cells. Cancer Res. 42:1130.
34. Kredich, N. M. and Martin. D. W., Jr. 1977, Role of S-adenosylhomocysteine in adenosine mediated toxicily in cultured mouse T lymphoma cells. Cell 12:931.
35. Ueland, P. M. 1982. Pharmacological and biochemical aspects of S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase. Pharmacol. Rev. 34:223.
36. Chiang, P. K., Burbelo, P. D., Brugh, S. A., Gordon, R., Fukuda, K. and Yamada, Y. 1992. Activation of collagen IV gene expression in F9 teratocarcinoma cells by 3-deazaadenosine analogs. J. Biol. Chem. 267:4988.
37. Medzihradsky, J. L., Zimmerman,T. P., Wolberg, G.and Elion, G. B. 1982. Immunsuppressive effects of the S-adenosylhomocysteine hydrolase inhibitor, 3-deazaadenosine. J. Immunpharmacol. 4:29.
38. Bader, J. P., Brown, N. R., Chiang, P. K. and Cantoni, G. L. 1978. 3-deazaadenosine, an inhibitor of adenosylhomocysteine hydrolase, inhibit reproduction of rous sarcoma virus and transformation of chick embryo cells. Virology 89:494.
39. Clarke, S. 1993. Protein methylation. Curr. Opin. Cell Biol. 5:977.
40. Cifone, M. G., de Maria, R., Roncaioli, P., Rippo. M. R., Azuma, M., Lanier, L. L., Santoni, A. andTesti, R. 1994. Apoptotic signaling through CD95 (Fas/APO-1 ) activates an acidic sphingomyelinase. J. Exp. Med. 177:1547
41. Bergmann, S., Shatrov, V., Ratter, F., Schiemann, S., Schulze-Osthoff, K. and Lehmann, V. 1994 Adenosine and homocysteine together enhance TNF-mediated cytotoxicity but do not alter activation of nuclear factor KB in L929 cells. J. Immunol. 153:1736.