Functional cloning of the miltefosine transporter: A novel p-type phospholipid translocase from leishmania involved in drug resistance

Journal of Biological Chemistry

Volumn 278, Issue 50, 2003, Pages 49965-49971

  Pérez Victoria, F Javier ^a   Gamarro, Francisco ^a   Ouellette, Marc ^b   Castanys, Santiago ^a  

^a INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; CELLS; CLONING; DRUG PRODUCTS; PATIENT TREATMENT; PHOSPHOLIPIDS; TUMORS;

PLASMA MEMBRANE;

BIOCHEMISTRY;

ADENOSINE TRIPHOSPHATASE; CARRIER PROTEIN; EDELFOSINE; GLYCEROPHOSPHOLIPID; MILTEFOSINE; PHOSPHOLIPID TRANSFER PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; DRUG RESISTANCE; ENDEMIC DISEASE; ENDOCYTOSIS; GENE LOCUS; GENE OVEREXPRESSION; GENETIC TRANSFECTION; LEISHMANIA; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHOLIPID TRANSFER; POINT MUTATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TUMOR CELL CULTURE; VISCERAL LEISHMANIASIS;

ADENOSINE TRIPHOSPHATASES; ALLELES; AMINO ACID SEQUENCE; ANIMALS; ANTIPROTOZOAL AGENTS; BIOLOGICAL TRANSPORT; BLOTTING, SOUTHERN; CARRIER PROTEINS; CELL MEMBRANE; CHROMOSOME MAPPING; CLONING, MOLECULAR; COSMIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; GENOTYPE; IMMUNOBLOTTING; LEISHMANIA DONOVANI; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICROSCOPY, FLUORESCENCE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; PHENOTYPE; PHOSPHODIESTERASE INHIBITORS; PHOSPHOLIPID ETHERS; PHOSPHOLIPID TRANSFER PROTEINS; PHOSPHORYLCHOLINE; PLASMIDS; POINT MUTATION; PROTOZOAN PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFECTION;

ANIMALIA; EUKARYOTA; LEISHMANIA DONOVANI; LEISHMANIA TARENTOLAE;

EID: 0346118937     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M308352200     Document Type: Article

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