Nonsense mutations in close proximity to the initiation codon fail to trigger full nonsense-mediated mRNA decay

Journal of Biological Chemistry

Volumn 279, Issue 31, 2004, Pages 32170-32180

  Inácios, Ângela ^a   Silva, Ana Luísa ^a   Pinto, Joana ^a   Ji, Xinjun ^b   Morgado, Ana ^a   Almeida, Fátima ^a   Faustino, Paula ^a   Lavinha, João ^a   Liebhaber, Stephen A ^b   Romão, Luísa ^a  

^a NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE   (Portugal)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; GENES;

MAMMALIAN CELLS; MUTATIONS;

RNA;

BETA GLOBIN; BETA GLOBIN MESSENGER RNA; BETA WT MESSENGER RNA; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BETA GLOBIN GENE; BETA THALASSEMIA GENE; CODON; CONTROLLED STUDY; ERYTHROID CELL; EXON; GENE; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; MAMMAL CELL; MOUSE; NONHUMAN; NONSENSE MEDIATED MESSENGER RNA DECAY; NONSENSE MUTATION; PRIORITY JOURNAL; PROMOTER REGION; RNA DEGRADATION; RNA SPLICING; RNA STABILITY; RNA TRANSLATION; STOP CODON; TERMINATION CODON; TRANSLATION INITIATION;

ANIMALS; CELL LINE; CODON; CODON, INITIATOR; CODON, NONSENSE; CODON, TERMINATOR; DNA; EXONS; GENES, DOMINANT; GLOBINS; HELA CELLS; HUMANS; INTRONS; MICE; MUTATION; OLIGONUCLEOTIDES; OPEN READING FRAMES; PLASMIDS; POLYRIBOSOMES; PROMOTER REGIONS (GENETICS); PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, TERTIARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIBONUCLEASES; RNA SPLICING; RNA, MESSENGER; SUCROSE; TIME FACTORS; TRANSFECTION;

ANIMALIA; MAMMALIA;

EID: 3543012545     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M405024200     Document Type: Article

References (56)

1. Wagner, E., and Lykke-Andersen, J. (2002) J. Cell Sci. 115, 3033-3038
2. Maquat, L. E. (1995) RNA (N. Y.) 1, 453-465
3. Kozak, M. (2002) Mamm. Genome. 13, 401-410
4. Maquat, L. E. (2004) Nat. Rev. Mol. Cell. Biol. 5, 89-99
5. Blencowe, B. J., Issner, R., Nickerson, J. A., and Sharp, P. A. (1998) Genes Dev. 12, 996-1009
6. Mayeda, A., Badolato, J., Kobayashi, R., Zhang, M. Q., Gardiner, E. M., and Krainer, A. R. (1999) EMBO J. 18, 4560-4570
7. Kataoka, N., Yong, J., Kim, V. N., Velazquez, F., Perkinson, R. A., Wang, F., and Dreyfuss, G. (2000) Mol. Cell 6, 673-682
8. Le Hir, H., Izaurralde, E., Maquat, L. E., and Moore, M. J. (2000) EMBO J. 19, 6860-6869
9. Le Hir, H., Moore, M. J., and Maquat, L. E. (2000) Genes Dev. 14, 1098-1108
10. Zhou, Z., Luo, M. J., Straesser, K., Katahira, J., Hurt, E., and Reed, R. (2000) Nature 407, 401-405
11. Kim, V. N., Kataoka, N., and Dreyfuss, G. (2001) Science 293, 1832-1836
12. Kim, V. N., Yong, J., Kataoka, N., Abel, L., Diem, M. D., and Dreyfuss, G. (2001) EMBO J. 20, 2062-2068
13. Lykke-Andersen, J., Shu, M.-D., and Steitz, J. A. (2001) Science 293, 1836-1839
14. Le Hir, H., Gatfield, D., Izaurralde, E., and Moore, M. J. (2001) EMBO J. 20, 4987-4997
15. Le Hir, H., Gatfield, D., Braun, I. C., Forler, D., and Izaurralde, E. (2001) EMBO Rep. 2, 1119-1124
16. Kataoka, N., Diem, M. D., Kim, V. N., Yong, J., and Dreyfuss, G. (2001) EMBO J. 20, 6424-6433
17. Gehring, N. H., Neu-Yilik, G., Schell, T., Hentze, M. W., and Kulozik, A. E. (2003) Mol. Cell 11, 939-949
18. Kataoka, N., and Dreyfuss, G. (2004) J. Biol. Chem. 20, 7009-7013
19. Lykke-Andersen, J., Shu, M.-D., and Steitz, J. A. (2000) Cell 103, 1121-1131
20. Serin, G., Gersappe, A., Black, J. D., Aronoff, R., and Maquat, L. E. (2001) Mol. Cell Biol. 21, 209-223
21. Ishigaki, Y., Li, X., Serin, G., and Maquat, L. E. (2001) Cell 106, 607-617
22. Pal, M., Ishigaki, Y., Nagy, E., and Maquat, L. E. (2001) RNA (N. Y.) 7, 5-15
23. Ohnishi, T., Yamashita, A., Kashima, A., Schell, T., Andres K. R., Grimson, A., Hachiya, T., Hentze, M. W., Andersen, P., and Ohno, S. (2003) Mol. Cell 12, 1187-1200
24. He, F., Brown, A. H., and Jacobson, A. (1997) Mol. Cell. Biol. 17, 1580-1594
25. Mendell, J. T., Medghalchi, S. M., Lake, R. G., Noensie, E. N., and Dietz, H. C. (2000) Mol. Cell. Biol. 20, 8944-8957
26. Schell, T., Kocher, T., Wilm, M., Seraphin, B., Kulozik, A., and Hentze, M. W. (2003) Biochem. J. 373, 775-783
27. Czaplinski, K., Ruiz-Echevarria, M. J., Paushkin, S. V., Han, X., Weng, Y., Perlick, H. A., Dietz, H. C., Ter-Avanesyan, M. D., and Peltz, S. W. (1998) Genes Dev. 12, 1665-1677
28. Zhang, J., Sun, X., Qian, Y., and Maquat, L. E. (1998) RNA (N. Y.) 4, 801-815
29. Thermann, R., Neu-Yilik, G., Deters, A., Frede, U., Wehr, K., Hagemeier, C., Hentze, M. W., and Kulozik, A. E. (1998) EMBO J. 17, 3484-3494
30. Zhang, J., Sun, X., Qian, Y., and Maquat, L. E. (1998) Mol. Cell. Biol. 18, 5272-5283
31. Zhang, J., and Maquat, L. E. (1997) EMBO J. 16, 826-833
32. Buzina, A., and Shulman, M. J. (1999) Mol. Biol. Cell 10, 515-524
33. Perrin-Vidoz, L., Sinilnikova, O. M., Stoppa-Lyonnet, D., Lenoir, G. M., and Mazoyer, S. (2002) Hum. Mol. Genet. 11, 2805-2814
34. Wang, J., Gudikote, J. P., Olivas, O. R., and Wilkinson, M. F. (2002) EMBO Rep. 3, 274-279
35. Asselta, R., Duga, S., Spena, S., Santagostino, E., Peyvandi, F., Piseddu, G., Targhetta, R., Malcovati, M., Mannucci, P. M., and Tenchini, M. L. (2001) Blood 98, 3685-3692
36. Denecke, J., Kranz, C., Kemming, D., Koch, H.-G., and Marquardt, T. (2004) Hum. Mutat. 23, 477-486
37. Romão, L., Inácio, A., Santos, S., Ávila, M., Faustino, P., Pacheco, P., and Lavinha, J. (2000) Blood 96, 2895-2901
38. Ji, X., Kong, J., and Liebhaber, S. A. (2003) Mol. Cell. Biol. 23, 899-907
39. Kong, J., Ji, X., and Liebhaber, S. A. (2003) Mol. Cell. Biol. 23, 1125-1134
40. Liebhaber, S. A., Wang, Z., Cash, F. E., Monks, B., and Russel, J. E. (1996) Mol. Cell. Biol. 16, 2637-2646
41. Baserga, S., and Benz, E. J., Jr. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 2056-2060
42. Couttet, P., and Grange, T. (2004) Nucleic Acids Res. 32, 488-494
43. Stevens, A., Wang, Y., Bremer, K., Zhang, J., Hoepfner, R., Antoniou, M., Scheuberg, D. R., and Maquat, L. E. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 12741-12746
44. Orkin, S. H., Kazazian, H. H., Jr., Antonarakis, S. E., Oster, H., Goff, Sc., and Sexton, J. P. (1982) Nature 300, 768-769
45. Goldsmith, M. E., Humphries, R. K., Ley, T., Cline, A., Kantor, J. A., and Nienhuis, A. W. (1983) Proc. Natl. Acad. Sci. U. S. A. 80, 2318-2322
46. Orkin, S. H., Antonarakis, S. E., and Loukopoulos, D. (1984) Blood 64, 311-313
47. Yang, K. G., Kutlar, F., George, E., Wilson, J. B., Kutlar, A., Stoming, T. A., Gonzalez-Redondo, J. M., and Huisman, T. H. J. (1989) Br. J. Haematol. 72, 73-80
48. Kozak, M. (1997) EMBO J. 16, 2482-2492
49. Hinnebusch, A. G. (1993) Mol. Cell. Biol. 10, 215-223
50. Janzen, D. M., Frolova, L., and Geballe, A. P. (2002) Mol. Cell. Biol. 22, 8562-8570
51. Yu, X., and Warner, J. R. (2001) J. Biol. Chem. 276, 33821-33825
52. Thein, S. L., Hesketh, C., Taylor, P., Temperley, I. J., Hutchinson, R. M., Old, J., Wood, W. G., Clegg, J. B., and Weatherall D. J. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 3924-3928
53. Hall, G. H., and Thein, S. (1994) Blood 83, 2031-2037
54. Lovett, P. S., and Rogers, E. J. (1996) Microbiol. Rev. 60, 366-385
55. Morris, D. R., and Geballe, P. (2000) Mol. Cell. Biol. 20, 8635-8642
56. Tenson, T., and Ehrenberg, M. (2002) Cell 108, 591-594