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Volumn 27, Issue 5 A, 2007, Pages 3345-3353

Promoter hypermethylation and quantitative expression analysis of CDKN2A (p14ARF and p16INK4a) gene in esophageal squamous cell carcinoma

Author keywords

Esophageal squamous cell carcinoma; Methylation; Methylation specific PCR; p14ARF; p16INK4a; Prognosis; Real time quantitative RT PCR

Indexed keywords

PROTEIN P14ARF; PROTEIN P16INK4A;

EID: 35348965692     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (20)

References (45)
  • 1
    • 10044292929 scopus 로고    scopus 로고
    • Three-field lymphadenectomy for carcinoma of the esophagus and gastroesophageal junction in 174 R0 resections: Impact on staging, disease-free survival, and outcome: a plea for adaptation of TNM classification in upper-half esophageal carcinoma
    • Lerut T, Nafteux P, Moons J, Coosemans W, Decker G, De Leyn P, Van Raemdonck D and Ectors N: Three-field lymphadenectomy for carcinoma of the esophagus and gastroesophageal junction in 174 R0 resections: impact on staging, disease-free survival, and outcome: a plea for adaptation of TNM classification in upper-half esophageal carcinoma. Ann Surg 240: 962-974, 2004.
    • (2004) Ann Surg , vol.240 , pp. 962-974
    • Lerut, T.1    Nafteux, P.2    Moons, J.3    Coosemans, W.4    Decker, G.5    De Leyn, P.6    Van Raemdonck, D.7    Ectors, N.8
  • 2
    • 0035756001 scopus 로고    scopus 로고
    • Outcomes of extended lymph node dissection for squamous cell carcinoma of the thoracic esophagus
    • Tsurumaru M, Kajiyama Y, Udagawa H and Akiyama H: Outcomes of extended lymph node dissection for squamous cell carcinoma of the thoracic esophagus. Ann Thorac Cardiovasc Surg 7: 325-329, 2001.
    • (2001) Ann Thorac Cardiovasc Surg , vol.7 , pp. 325-329
    • Tsurumaru, M.1    Kajiyama, Y.2    Udagawa, H.3    Akiyama, H.4
  • 3
    • 0034113807 scopus 로고    scopus 로고
    • Genetic steps in the development of squamous cell carcinoma of the esophagus
    • Mandard AM, Hainaut P and Hollstein M: Genetic steps in the development of squamous cell carcinoma of the esophagus. Mutat Res 462: 335-342, 2000.
    • (2000) Mutat Res , vol.462 , pp. 335-342
    • Mandard, A.M.1    Hainaut, P.2    Hollstein, M.3
  • 4
    • 0031710479 scopus 로고    scopus 로고
    • The INK4a/ARF tumor suppressor: One gene-two products-two pathways
    • Chin L, Pomerantz J and DePinho RA: The INK4a/ARF tumor suppressor: one gene-two products-two pathways. Trends Biochem Sci 23: 291-296, 1998.
    • (1998) Trends Biochem Sci , vol.23 , pp. 291-296
    • Chin, L.1    Pomerantz, J.2    DePinho, R.A.3
  • 8
    • 0032418416 scopus 로고    scopus 로고
    • A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice
    • Holland EC, Hively WP, DePinho RA and Varmus HE: A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. Genes Dev 12: 3675-3685, 1998.
    • (1998) Genes Dev , vol.12 , pp. 3675-3685
    • Holland, E.C.1    Hively, W.P.2    DePinho, R.A.3    Varmus, H.E.4
  • 9
    • 0033569423 scopus 로고    scopus 로고
    • INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53
    • Schmitt CA, McCurrach ME, de Stanchina E, Wallace-Brodeur RR and Lowe SW: INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53. Genes Dev 13: 2670-2677, 1999.
    • (1999) Genes Dev , vol.13 , pp. 2670-2677
    • Schmitt, C.A.1    McCurrach, M.E.2    de Stanchina, E.3    Wallace-Brodeur, R.R.4    Lowe, S.W.5
  • 10
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • Jones PA and Laird PW: Cancer epigenetics comes of age. Nature Genet 21: 163-167, 1999.
    • (1999) Nature Genet , vol.21 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 12
    • 0034077361 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations in carcinogenesis
    • Sugimura T and Ushijima T: Genetic and epigenetic alterations in carcinogenesis. Mutat Res 462: 235-246, 2000.
    • (2000) Mutat Res , vol.462 , pp. 235-246
    • Sugimura, T.1    Ushijima, T.2
  • 13
  • 14
    • 0036799084 scopus 로고    scopus 로고
    • Detection of multiple gene hypermethylation in the development of esophageal squamous cell carcinoma
    • Nie Y, Liao J, Zhao X, Song Y, Yang GY, Wang LD and Yang CS: Detection of multiple gene hypermethylation in the development of esophageal squamous cell carcinoma. Carcinogenesis 23: 1713-1720, 2002.
    • (2002) Carcinogenesis , vol.23 , pp. 1713-1720
    • Nie, Y.1    Liao, J.2    Zhao, X.3    Song, Y.4    Yang, G.Y.5    Wang, L.D.6    Yang, C.S.7
  • 18
    • 0027992428 scopus 로고
    • Multiple occurrence of carcinoma in the upper aerodigestive tract associated with esophageal cancer: Reference to smoking, drinking and family history
    • Morita M, Kuwano H, Ohno S, Sugimachi K, Seo Y, Tomoda H, Furusawa M and Nakashima T: Multiple occurrence of carcinoma in the upper aerodigestive tract associated with esophageal cancer: reference to smoking, drinking and family history. Int J Cancer 58: 207-210, 1994.
    • (1994) Int J Cancer , vol.58 , pp. 207-210
    • Morita, M.1    Kuwano, H.2    Ohno, S.3    Sugimachi, K.4    Seo, Y.5    Tomoda, H.6    Furusawa, M.7    Nakashima, T.8
  • 19
    • 0036160628 scopus 로고    scopus 로고
    • The relationship of alcohol consumption and cigarette smoking to the multiple occurrence of esophageal dysplasia and squamous cell carcinoma
    • Miyazaki M, Ohno S, Futatsugi M, Saeki H, Ohga T and Watanabe M: The relationship of alcohol consumption and cigarette smoking to the multiple occurrence of esophageal dysplasia and squamous cell carcinoma. Surgery 131: 7-13, 2002.
    • (2002) Surgery , vol.131 , pp. 7-13
    • Miyazaki, M.1    Ohno, S.2    Futatsugi, M.3    Saeki, H.4    Ohga, T.5    Watanabe, M.6
  • 20
    • 0034026918 scopus 로고    scopus 로고
    • Alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumlation in oesophageal squamous cell carcinoma in the Japanese
    • Saeki H, Ohno S, Araki K, Egashira A, Kawaguchi H, Ikeda Y, Morita M, Kitamura K and Sugimachi K: Alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumlation in oesophageal squamous cell carcinoma in the Japanese. Br J Cancer 82: 1892-1894, 2000.
    • (2000) Br J Cancer , vol.82 , pp. 1892-1894
    • Saeki, H.1    Ohno, S.2    Araki, K.3    Egashira, A.4    Kawaguchi, H.5    Ikeda, Y.6    Morita, M.7    Kitamura, K.8    Sugimachi, K.9
  • 25
    • 0033764297 scopus 로고    scopus 로고
    • Application of quantitative RT-PCR using "TaqMan" technology to evaluate the expression of CK 18 mRNA in various cell lines
    • Tokunaga E, Maehara Y, Oki E, Koga T, Kakeji Y and Sugimachi K: Application of quantitative RT-PCR using "TaqMan" technology to evaluate the expression of CK 18 mRNA in various cell lines. J Exp Clin Cancer Res 19: 375-381, 2000.
    • (2000) J Exp Clin Cancer Res , vol.19 , pp. 375-381
    • Tokunaga, E.1    Maehara, Y.2    Oki, E.3    Koga, T.4    Kakeji, Y.5    Sugimachi, K.6
  • 26
    • 0025982062 scopus 로고
    • Construction of T-vectors, a rapid and general system for direct cloning of unmodified PCR products
    • Marchuk D, Drumm M, Saulino A and Collins FS: Construction of T-vectors, a rapid and general system for direct cloning of unmodified PCR products. Nucleic Acids Res 19: 1154, 1991.
    • (1991) Nucleic Acids Res , vol.19 , pp. 1154
    • Marchuk, D.1    Drumm, M.2    Saulino, A.3    Collins, F.S.4
  • 27
    • 0036166191 scopus 로고    scopus 로고
    • Risk factors for esophageal cancer and the multiple occurrence of carcinoma in the upper aerodigestive tract
    • Morita M, Saeki H, Mori M, Kuwano H and Sugimachi K: Risk factors for esophageal cancer and the multiple occurrence of carcinoma in the upper aerodigestive tract. Surgery 131: S1-6, 2002.
    • (2002) Surgery , vol.131
    • Morita, M.1    Saeki, H.2    Mori, M.3    Kuwano, H.4    Sugimachi, K.5
  • 29
    • 0034796682 scopus 로고    scopus 로고
    • Molecular detection of p16 promoter methylation in the serum of patient with esophageal squamous cell carcinoma
    • Hibi K, Taguchi M, Nakayama H, Takase T, Kasai Y, Ito K, Akiyama S and Nakao A: Molecular detection of p16 promoter methylation in the serum of patient with esophageal squamous cell carcinoma. Clin Cancer Res 7: 3135-3138, 2001.
    • (2001) Clin Cancer Res , vol.7 , pp. 3135-3138
    • Hibi, K.1    Taguchi, M.2    Nakayama, H.3    Takase, T.4    Kasai, Y.5    Ito, K.6    Akiyama, S.7    Nakao, A.8
  • 30
    • 8644260860 scopus 로고    scopus 로고
    • p53 Mutation profiling of multiple esophageal carcinoma using laser capture microdissection to demonstrate field carcinogenesis
    • Ito S, Ohga T, Saeki H, Nakamura T, Watanabe M, Tanaka S, Kakeji Y and Maehara Y: p53 Mutation profiling of multiple esophageal carcinoma using laser capture microdissection to demonstrate field carcinogenesis. Int J Cancer 113: 22-28, 2005.
    • (2005) Int J Cancer , vol.113 , pp. 22-28
    • Ito, S.1    Ohga, T.2    Saeki, H.3    Nakamura, T.4    Watanabe, M.5    Tanaka, S.6    Kakeji, Y.7    Maehara, Y.8
  • 33
    • 0037068312 scopus 로고    scopus 로고
    • CpG island hypermethylation and tumor suppressor genes: A booming present, a brighter future
    • Esteller M: CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene 21: 5427-5440, 2002.
    • (2002) Oncogene , vol.21 , pp. 5427-5440
    • Esteller, M.1
  • 36
    • 9444268107 scopus 로고    scopus 로고
    • Inactivation of the CDKN2 gene by homozygous deletion and de novo methylation is associated with advanced stage esophageal squamous cell carcinoma
    • Maesawa C, Tamura G, Nishizuka S, Ogasawara S, Ishida K, Terashima M, Sakata K, Sato N, Saito K and Satodate R: Inactivation of the CDKN2 gene by homozygous deletion and de novo methylation is associated with advanced stage esophageal squamous cell carcinoma. Cancer Res 56: 3875-3878, 1996.
    • (1996) Cancer Res , vol.56 , pp. 3875-3878
    • Maesawa, C.1    Tamura, G.2    Nishizuka, S.3    Ogasawara, S.4    Ishida, K.5    Terashima, M.6    Sakata, K.7    Sato, N.8    Saito, K.9    Satodate, R.10
  • 43
    • 0030795157 scopus 로고    scopus 로고
    • Frequent loss of p16 expression and its correlation with clinicopathological parameters in pancreatic carcinoma
    • Hu YX, Watanabe H, Ohtsubo K, Yamaguchi Y, Ha A, Okai T and Sawabu N: Frequent loss of p16 expression and its correlation with clinicopathological parameters in pancreatic carcinoma. Clin Cancer Res 3: 1473-1477, 1997.
    • (1997) Clin Cancer Res , vol.3 , pp. 1473-1477
    • Hu, Y.X.1    Watanabe, H.2    Ohtsubo, K.3    Yamaguchi, Y.4    Ha, A.5    Okai, T.6    Sawabu, N.7
  • 44
    • 0031426989 scopus 로고    scopus 로고
    • Altered p16/MTS1/CDKN2 and cyclin D1/PRAD-1 gene expression is associated with the prognosis of squamous cell carcinoma of the esophagus
    • Takeuchi H, Ozawa S, Ando N, Shih CH, Koyanagi K, Ueda M and Kitajima M: Altered p16/MTS1/CDKN2 and cyclin D1/PRAD-1 gene expression is associated with the prognosis of squamous cell carcinoma of the esophagus. Clin Cancer Res 3: 2229-2236, 1997.
    • (1997) Clin Cancer Res , vol.3 , pp. 2229-2236
    • Takeuchi, H.1    Ozawa, S.2    Ando, N.3    Shih, C.H.4    Koyanagi, K.5    Ueda, M.6    Kitajima, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.