-
3
-
-
0001510491
-
The RB p53 pathways in cancer
-
Sherr CJ, McCormick F. The RB and p53 pathways in cancer. Cancer Cell 2002;2:103-12.
-
(2002)
Cancer Cell
, vol.2
, pp. 103-112
-
-
Sherr, C.J.1
McCormick, F.2
-
4
-
-
0029587551
-
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
-
Quelle DE, Zindy F, Ashmun RA, Sherr CJ. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell 1995;83:993-1000.
-
(1995)
Cell
, vol.83
, pp. 993-1000
-
-
Quelle, D.E.1
Zindy, F.2
Ashmun, R.A.3
Sherr, C.J.4
-
5
-
-
0036178622
-
Aberrations in the MTS1 tumor suppressor locus in oral squamous cell carcinoma lines preferentially affect the INK4A gene and result in increased cdk6 activity
-
Piboonniyom SO, Timmermann S, Hinds P, Munger K. Aberrations in the MTS1 tumor suppressor locus in oral squamous cell carcinoma lines preferentially affect the INK4A gene and result in increased cdk6 activity. Oral Oncol 2002;38:179-86.
-
(2002)
Oral Oncol
, vol.38
, pp. 179-186
-
-
Piboonniyom, S.O.1
Timmermann, S.2
Hinds, P.3
Munger, K.4
-
6
-
-
0032589742
-
Cyclin D1 and P16INK4A expression predict reduced survival in carcinoma of the anterior tongue
-
Bova RJ, Quinn DI, Nankervis JS, et al. Cyclin D1 and P16INK4A expression predict reduced survival in carcinoma of the anterior tongue. Clin Cancer Res 1999;5:2810-9.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2810-2819
-
-
Bova, R.J.1
Quinn, D.I.2
Nankervis, J.S.3
-
8
-
-
0036899257
-
Mutated p53 as a molecular marker for the diagnosis of head and neck cancer
-
van Houten VM, Tabor MP, van den Brekel MW, et al. Mutated p53 as a molecular marker for the diagnosis of head and neck cancer. J Pathol 2002;198:476-86.
-
(2002)
J Pathol
, vol.198
, pp. 476-486
-
-
Van Houten, V.M.1
Tabor, M.P.2
Van Den Brekel, M.W.3
-
9
-
-
0036568390
-
Expression of p53 and its homologues in primary and recurrent squamous cell carcinomas of the head and neck
-
Weber A, Bellmann U, Bootz F, Wittekind C, Tannapfel A. Expression of p53 and its homologues in primary and recurrent squamous cell carcinomas of the head and neck. Int J Cancer 2002;99:22-8.
-
(2002)
Int J Cancer
, vol.99
, pp. 22-28
-
-
Weber, A.1
Bellmann, U.2
Bootz, F.3
Wittekind, C.4
Tannapfel, A.5
-
11
-
-
0032984992
-
Mechanisms of p53-mediated apoptosis
-
Bates S, Vousden KH. Mechanisms of p53-mediated apoptosis. Cell Mol Life Sci 1999;55:28-37.
-
(1999)
Cell Mol Life Sci
, vol.55
, pp. 28-37
-
-
Bates, S.1
Vousden, K.H.2
-
12
-
-
0032493350
-
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
-
Kamijo T, Weber JD, Zambetti G, Zindy F, Roussel MF, Sherr CJ. Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2. Proc Natl Acad Sci U S A 1998;95:8292-7.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 8292-8297
-
-
Kamijo, T.1
Weber, J.D.2
Zambetti, G.3
Zindy, F.4
Roussel, M.F.5
Sherr, C.J.6
-
13
-
-
0033536063
-
P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2
-
Tao W, Levine AJ. P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2. Proc Natl Acad Sci U S A 1999;96:6937-41.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 6937-6941
-
-
Tao, W.1
Levine, A.J.2
-
14
-
-
0033130010
-
Nucleolar Arf sequesters Mdm2 and activates p53
-
Weber JD, Taylor LJ, Roussel MF, Sherr CJ, Bar-Sagi D. Nucleolar Arf sequesters Mdm2 and activates p53. Nat Cell Biol 1999;1:20-6.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 20-26
-
-
Weber, J.D.1
Taylor, L.J.2
Roussel, M.F.3
Sherr, C.J.4
Bar-Sagi, D.5
-
15
-
-
0032549704
-
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
Pomerantz J, Schreiber-Agus N, Liegeois NJ, et al. The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 1998;92:713-23.
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liegeois, N.J.3
-
16
-
-
0034744224
-
Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus
-
Llanos S, Clark PA, Rowe J, Peters G. Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus. Nat Cell Biol 2001;3:445-52.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 445-452
-
-
Llanos, S.1
Clark, P.A.2
Rowe, J.3
Peters, G.4
-
17
-
-
0036133108
-
ARF function does not require p53 stabilization or Mdm2 relocalization
-
Korgaonkar C, Zhao L, Modestou M, Quelle DE. ARF function does not require p53 stabilization or Mdm2 relocalization. Mol Cell Biol 2002;22:196-206.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 196-206
-
-
Korgaonkar, C.1
Zhao, L.2
Modestou, M.3
Quelle, D.E.4
-
18
-
-
0036172197
-
Human tumor suppressor ARF impedes S-phase progression independent of p53
-
Yarbrough WG, Bessho M, Zanation A, Bisi JE, Xiong Y. Human tumor suppressor ARF impedes S-phase progression independent of p53. Cancer Res 2002;62:1171-7.
-
(2002)
Cancer Res
, vol.62
, pp. 1171-1177
-
-
Yarbrough, W.G.1
Bessho, M.2
Zanation, A.3
Bisi, J.E.4
Xiong, Y.5
-
19
-
-
0032504783
-
p14ARF links the tumour suppressors RB and p53
-
Bates S, Phillips AC, Clark PA, et al. p14ARF links the tumour suppressors RB and p53. Nature 1998;395:124-5.
-
(1998)
Nature
, vol.395
, pp. 124-125
-
-
Bates, S.1
Phillips, A.C.2
Clark, P.A.3
-
20
-
-
0029975913
-
Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity
-
Khleif SN, DeGregori J, Yee CL, et al. Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity. Proc Natl Acad Sci U S A 1996;93:4350-4.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 4350-4354
-
-
Khleif, S.N.1
DeGregori, J.2
Yee, C.L.3
-
21
-
-
0034961861
-
Inactivation of the p14(ARF), p15(INK4B) and p16(INK4A) genes is a frequent event in human oral squamous cell carcinomas
-
Shintani S, Nakahara Y, Mihara M, Ueyama Y, Matsumura T. Inactivation of the p14(ARF), p15(INK4B) and p16(INK4A) genes is a frequent event in human oral squamous cell carcinomas. Oral Oncol 2001;37:498-504.
-
(2001)
Oral Oncol
, vol.37
, pp. 498-504
-
-
Shintani, S.1
Nakahara, Y.2
Mihara, M.3
Ueyama, Y.4
Matsumura, T.5
-
22
-
-
0036373788
-
INK4a-ARF alterations and p53 mutations in primary and consecutive squamous cell carcinoma of the head and neck
-
Weber A, Bellmann U, Bootz F, Wittekind C, Tannapfel A. INK4a-ARF alterations and p53 mutations in primary and consecutive squamous cell carcinoma of the head and neck. Virchows Arch 2002;441:133-42.
-
(2002)
Virchows Arch
, vol.441
, pp. 133-142
-
-
Weber, A.1
Bellmann, U.2
Bootz, F.3
Wittekind, C.4
Tannapfel, A.5
-
23
-
-
9444255067
-
High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma
-
Reed AL, Califano J, Cairns P, et al. High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma. Cancer Res 1996;56:3630-3.
-
(1996)
Cancer Res
, vol.56
, pp. 3630-3633
-
-
Reed, A.L.1
Califano, J.2
Cairns, P.3
-
24
-
-
85047699497
-
Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2
-
Palmero I, Murga M, Zubiaga A, Serrano M. Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2. Oncogene 2002;21:2939-47.
-
(2002)
Oncogene
, vol.21
, pp. 2939-2947
-
-
Palmero, I.1
Murga, M.2
Zubiaga, A.3
Serrano, M.4
-
25
-
-
0036297530
-
Transcriptional regulation of the human tumor suppressor p14(ARF) by E2F1, E2F2, E2F3, and Sp1-like factors
-
Parisi T, Pollice A, Di Cristofano A, Calabro V, La Mantia G. Transcriptional regulation of the human tumor suppressor p14(ARF) by E2F1, E2F2, E2F3, and Sp1-like factors. Biochem Biophys Res Commun 2002;291:1138-45.
-
(2002)
Biochem Biophys Res Commun
, vol.291
, pp. 1138-1145
-
-
Parisi, T.1
Pollice, A.2
Di Cristofano, A.3
Calabro, V.4
La Mantia, G.5
-
26
-
-
0141456448
-
Overexpression of E2F-1 is associated with increased disease-free survival in squamous cell carcinoma of the anterior tongue
-
Kwong RA, Nguyen TV, Bova RJ, et al. Overexpression of E2F-1 is associated with increased disease-free survival in squamous cell carcinoma of the anterior tongue. Clin Cancer Res 2003;9:3705-11.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3705-3711
-
-
Kwong, R.A.1
Nguyen, T.V.2
Bova, R.J.3
-
27
-
-
0035350918
-
The application of tissue microarrays to cancer research
-
Horvath L, Henshall S. The application of tissue microarrays to cancer research. Pathology 2001;33:125-9.
-
(2001)
Pathology
, vol.33
, pp. 125-129
-
-
Horvath, L.1
Henshall, S.2
-
30
-
-
0034193416
-
Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus
-
Lindstrom MS, Klangby U, Inoue R, et al. Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus. Exp Cell Res 2000;256:400-10.
-
(2000)
Exp Cell Res
, vol.256
, pp. 400-410
-
-
Lindstrom, M.S.1
Klangby, U.2
Inoue, R.3
-
31
-
-
0030738479
-
Distinct roles for E2F proteins in cell growth control and apoptosis
-
DeGregori J, Leone G, Miron A, Jakoi L, Nevins JR. Distinct roles for E2F proteins in cell growth control and apoptosis. Proc Natl Acad Sci U S A 1997;94:7245-50.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 7245-7250
-
-
DeGregori, J.1
Leone, G.2
Miron, A.3
Jakoi, L.4
Nevins, J.R.5
-
32
-
-
0032169516
-
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2
-
Stott FJ, Bates S, James MC, et al. The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J 1998;17:5001-14.
-
(1998)
EMBO J
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
Bates, S.2
James, M.C.3
-
34
-
-
0028073875
-
Lymph node prognostic factors in head and neck squamous cell carcinomas
-
Mamelle G, Pampurik J, Luboinski B, Lancar R, Lusinchi A, Bosq J. Lymph node prognostic factors in head and neck squamous cell carcinomas. Am J Surg 1994;168:494-8.
-
(1994)
Am J Surg
, vol.168
, pp. 494-498
-
-
Mamelle, G.1
Pampurik, J.2
Luboinski, B.3
Lancar, R.4
Lusinchi, A.5
Bosq, J.6
-
35
-
-
0034519444
-
Molecular markers predictive of response and prognosis in the patient with advanced squamous cell carcinoma of the head and neck: Evolution of a model beyond TNM staging
-
Salesiotis AN, Cullen KJ. Molecular markers predictive of response and prognosis in the patient with advanced squamous cell carcinoma of the head and neck: evolution of a model beyond TNM staging. Curr Opin Oncol 2000;12:229-39.
-
(2000)
Curr Opin Oncol
, vol.12
, pp. 229-239
-
-
Salesiotis, A.N.1
Cullen, K.J.2
-
36
-
-
0345276485
-
Tumor suppressor ARF degrades B23, a nucleolar protein Involved in ribosome biogenesis and cell proliferation
-
Itahana K, Bhat KP, Jin A, et al. Tumor suppressor ARF degrades B23, a nucleolar protein Involved in ribosome biogenesis and cell proliferation. Mol Cell 2003;12:1151-64.
-
(2003)
Mol Cell
, vol.12
, pp. 1151-1164
-
-
Itahana, K.1
Bhat, K.P.2
Jin, A.3
-
37
-
-
0037291204
-
Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing
-
Sugimoto M, Kuo ML, Roussel MF, Sherr CJ. Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing. Mol Cell 2003;11:415-24.
-
(2003)
Mol Cell
, vol.11
, pp. 415-424
-
-
Sugimoto, M.1
Kuo, M.L.2
Roussel, M.F.3
Sherr, C.J.4
-
38
-
-
0037015678
-
Human p14(Arf): An exquisite sensor of morphological changes and of short-lived perturbations in cell cycle and in nucleolar function
-
David-Pfeuty T, Nouvian-Dooghe Y. Human p14(Arf): an exquisite sensor of morphological changes and of short-lived perturbations in cell cycle and in nucleolar function. Oncogene 2002;21:6779-90.
-
(2002)
Oncogene
, vol.21
, pp. 6779-6790
-
-
David-Pfeuty, T.1
Nouvian-Dooghe, Y.2
-
39
-
-
0035942177
-
Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation
-
Lin AW, Löwe SW. Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation. Proc Natl Acad Sci U S A 2001;98:5025-30.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5025-5030
-
-
Lin, A.W.1
Löwe, S.W.2
-
40
-
-
0035487104
-
The INK4a/ARF network in tumour suppression
-
Sherr CJ. The INK4a/ARF network in tumour suppression. Nat Rev Mol Cell Biol 2001;2:731-7.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 731-737
-
-
Sherr, C.J.1
-
41
-
-
0030728468
-
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
-
Kamijo T, Zindy F, Roussel MF, et al. Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell 1997;91:649-59.
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
-
42
-
-
0142258073
-
The tumor-suppressive functions of the human INK4A locus
-
Voorhoeve PM, Agami R. The tumor-suppressive functions of the human INK4A locus. Cancer Cell 2003;4:311-9.
-
(2003)
Cancer Cell
, vol.4
, pp. 311-319
-
-
Voorhoeve, P.M.1
Agami, R.2
-
43
-
-
0028108985
-
Database of p53 gene somatic mutations in human tumors and cell lines
-
Hollstein M, Rice K, Greenblatt MS, et al. Database of p53 gene somatic mutations in human tumors and cell lines. Nucleic Acids Res 1994;22:3551-5.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 3551-3555
-
-
Hollstein, M.1
Rice, K.2
Greenblatt, M.S.3
-
44
-
-
0032517341
-
The p16INK4a/CDKN2A tumor suppressor and its relatives
-
Ruas M, Peters G. The p16INK4a/CDKN2A tumor suppressor and its relatives. Biochim Biophys Acta 1998;1378:F115-77.
-
(1998)
Biochim Biophys Acta
, vol.1378
-
-
Ruas, M.1
Peters, G.2
-
45
-
-
0028239526
-
Overexpression of p53 protein in squamous cell carcinomas of head and neck without apparent gene mutations
-
Xu L, Chen YT, Huvos AG, et al. Overexpression of p53 protein in squamous cell carcinomas of head and neck without apparent gene mutations. Diagn Mol Pathol 1994;3:83-92.
-
(1994)
Diagn Mol Pathol
, vol.3
, pp. 83-92
-
-
Xu, L.1
Chen, Y.T.2
Huvos, A.G.3
-
46
-
-
0032504784
-
p19ARF links the tumour suppressor p53 to Ras
-
Palmero I, Pantoja C, Serrano M. p19ARF links the tumour suppressor p53 to Ras. Nature 1998;395:125-6.
-
(1998)
Nature
, vol.395
, pp. 125-126
-
-
Palmero, I.1
Pantoja, C.2
Serrano, M.3
-
47
-
-
0033614298
-
1 cyclin-dependent kinase activation by interacting with MDM2 and activating p53 in mouse fibroblasts
-
1 cyclin-dependent kinase activation by interacting with MDM2 and activating p53 in mouse fibroblasts. Oncogene 1999;18:2718-27.
-
(1999)
Oncogene
, vol.18
, pp. 2718-2727
-
-
Kurokawa, K.1
Tanaka, T.2
Kato, J.3
-
48
-
-
0034665749
-
p53-independent functions of the p19(ARF) tumor suppressor
-
Weber JD, Jeffers JR, Rehg JE, et al. p53-independent functions of the p19(ARF) tumor suppressor. Genes Dev 2000;14:2358-65.
-
(2000)
Genes Dev
, vol.14
, pp. 2358-2365
-
-
Weber, J.D.1
Jeffers, J.R.2
Rehg, J.E.3
-
49
-
-
0035300415
-
The alternative reading frame tumor suppressor inhibits growth through p21-dependent and p21-independent pathways
-
Modestou M, Puig-Antich V, Korgaonkar C, Eapen A, Quelle DE. The alternative reading frame tumor suppressor inhibits growth through p21-dependent and p21-independent pathways. Cancer Res 2001;61:3145-50.
-
(2001)
Cancer Res
, vol.61
, pp. 3145-3150
-
-
Modestou, M.1
Puig-Antich, V.2
Korgaonkar, C.3
Eapen, A.4
Quelle, D.E.5
|