Folate deficiency enhances arsenic effects on expression of genes involved in epidermal differentiation in transgenic K6/ODC mouse skin

Toxicology

Volumn 241, Issue 3, 2007, Pages 134-145

  Nelson, Gail M ^a   Ahlborn, Gene J ^a   Delker, Don A ^a   Kitchin, Kirk T ^a   O'Brien, Thomas G ^b   Chen, Yan ^b   Kohan, Michael J ^a   Roop, Barbara C ^a   Ward, William O ^a   Allen, James W ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b ODC Mouse Group Inc   (United States)

Author keywords

Epidermal differentiation; Folate deficiency; Gene expression; ODC transgenic mouse; Skin; Sodium arsenite

Indexed keywords

ARSENIC; DRINKING WATER; FOLIC ACID; HOMOCYSTEINE; INVOLUCRIN; LORICRIN; RNA; TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; EPIDERMIS; EPIDERMIS CELL; FEMALE; FOLIC ACID DEFICIENCY; GENE EXPRESSION; GENE FUNCTION; HAIR GROWTH; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE METABOLISM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN TRANSPORT; SKIN CARCINOGENESIS; SKIN TUMOR;

ANIMALS; ARSENITES; BINDING SITES; CARCINOGENS, ENVIRONMENTAL; CELL DIFFERENTIATION; CELL PROLIFERATION; EPIDERMIS; FEMALE; FOLIC ACID; FOLIC ACID DEFICIENCY; GENE EXPRESSION; GENE EXPRESSION PROFILING; HOMOCYSTEINE; MICE; MICE, TRANSGENIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SKIN; SKIN NEOPLASMS; SODIUM COMPOUNDS; TRANSCRIPTION FACTORS;

ANIMALIA; MUS; MUS MUSCULUS;

EID: 35348954732     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.08.094     Document Type: Article

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