메뉴 건너뛰기




Volumn 130, Issue 2, 2000, Pages 129-132

Folate and carcinogenesis: An integrated scheme

Author keywords

Carcinogenesis; DNA integrity; DNA methylation; Folate; MTHFR gene

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); FOLIC ACID;

EID: 0033970043     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/130.2.129     Document Type: Review
Times cited : (824)

References (35)
  • 1
    • 0033007272 scopus 로고    scopus 로고
    • Folate and carcinogenesis: Evidence, mechanisms, and implications
    • Kim, Y.I. (1999) Folate and carcinogenesis: Evidence, mechanisms, and implications. J. Nutr. Biochem. 10: 66-88.
    • (1999) J. Nutr. Biochem. , vol.10 , pp. 66-88
    • Kim, Y.I.1
  • 2
    • 0026795472 scopus 로고
    • Folate deficiency enhances the development of colonic neoplasia in dimethylhydrazine-treated rats
    • Cravo, M.L., Mason, J.B., Dayal, Y., Hutchinson, M., Smith, D., Selhub, J. & Rosenberg, I.H. (1992) Folate Deficiency Enhances the Development of Colonic Neoplasia in Dimethylhydrazine-treated Rats. Cancer Res. 52: 5002-5006.
    • (1992) Cancer Res. , vol.52 , pp. 5002-5006
    • Cravo, M.L.1    Mason, J.B.2    Dayal, Y.3    Hutchinson, M.4    Smith, D.5    Selhub, J.6    Rosenberg, I.H.7
  • 3
    • 0030452582 scopus 로고    scopus 로고
    • Dietary folate protects against the development of macroscopic colonic neoplasia in a dose responsive manner in rats
    • Kim, Y.I., Salomon, R.N., Graeme-Cook, F., Choi, S.W., Smith, D.E., Dallal, G.E. & Mason, J.B. (1996 a). Dietary folate protects against the development of macroscopic colonic neoplasia in a dose responsive manner in rats. Gut 39: 732-740.
    • (1996) Gut , vol.39 , pp. 732-740
    • Kim, Y.I.1    Salomon, R.N.2    Graeme-Cook, F.3    Choi, S.W.4    Smith, D.E.5    Dallal, G.E.6    Mason, J.B.7
  • 4
  • 6
    • 0016435386 scopus 로고
    • Hepatocarcinogenesis by diethynitrosamine in rats fed high dietary levels of lipotropes
    • Poirier, L.A. (1975) Hepatocarcinogenesis by diethynitrosamine in rats fed high dietary levels of lipotropes. J. Natl. Cancer Inst. 54: 137-140.
    • (1975) J. Natl. Cancer Inst. , vol.54 , pp. 137-140
    • Poirier, L.A.1
  • 7
    • 0020473008 scopus 로고
    • Improvement in cervical dysplasia associated with folic acid therapy in users of oral contraceptives
    • Butterworth Jr, C.E., Hatch, K.D., Gore, H., Mueller, H. & Krumdieck, C.L. (1982) Improvement in cervical dysplasia associated with folic acid therapy in users of oral contraceptives. Am. J. Clin. Nutr. 35: 73-82.
    • (1982) Am. J. Clin. Nutr. , vol.35 , pp. 73-82
    • Butterworth C.E., Jr.1    Hatch, K.D.2    Gore, H.3    Mueller, H.4    Krumdieck, C.L.5
  • 9
    • 0028347021 scopus 로고
    • Folate deficiency induced homocysteinemia in rats: Disruption of S-adenosylmethionine coordinate regulation of homocysteine metabolism
    • Miller, J.W., Nadeau, M.R., Smith, J., Smith, D. & Selhub, J. (1994) Folate deficiency induced homocysteinemia in rats: disruption of S-adenosylmethionine coordinate regulation of homocysteine metabolism. Biochem. J. 298: 415-419.
    • (1994) Biochem. J. , vol.298 , pp. 415-419
    • Miller, J.W.1    Nadeau, M.R.2    Smith, J.3    Smith, D.4    Selhub, J.5
  • 10
    • 0024371483 scopus 로고
    • Rapid appearance of hypermethylated DNA in livers of rats fed cancer promoting, methyl-deficient diets
    • Wainfan, E., Dizik, M., Stender, M. & Christman, J.K. (1989) Rapid appearance of hypermethylated DNA in livers of rats fed cancer promoting, methyl-deficient diets. Cancer Res. 49: 4094-4097.
    • (1989) Cancer Res. , vol.49 , pp. 4094-4097
    • Wainfan, E.1    Dizik, M.2    Stender, M.3    Christman, J.K.4
  • 12
    • 0031816123 scopus 로고    scopus 로고
    • Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women
    • Jacob, R.A., Gretz, D.M., Taylor, P.C., James, S.J., Pogribny, I.P., Miller, B.J., Henning, S.M. & Sendseid, M.E. (1998) Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women. J. Nutr. 128: 1204-1212.
    • (1998) J. Nutr. , vol.128 , pp. 1204-1212
    • Jacob, R.A.1    Gretz, D.M.2    Taylor, P.C.3    James, S.J.4    Pogribny, I.P.5    Miller, B.J.6    Henning, S.M.7    Sendseid, M.E.8
  • 14
  • 15
    • 0029815819 scopus 로고    scopus 로고
    • Exon-specific DNA hypomethylation of the p53 gene of rat colon induced by dimethylhydrazine. Modulation by dietary folate
    • Kim, Y.I., Pogribny, I.P., Salomon, R.N., Choi, S.W., Smith, D.E., James, S.J. & Mason, J. B. (1996 b) Exon-specific DNA hypomethylation of the p53 gene of rat colon induced by dimethylhydrazine. Modulation by dietary folate. Am. J. Pathol. 149: 1129-1137.
    • (1996) Am. J. Pathol. , vol.149 , pp. 1129-1137
    • Kim, Y.I.1    Pogribny, I.P.2    Salomon, R.N.3    Choi, S.W.4    Smith, D.E.5    James, S.J.6    Mason, J.B.7
  • 16
    • 0028794055 scopus 로고
    • A cytosine methyltransferase converts 5-methylcytosine in DNA to thymine
    • Yerba, M.J. & Bhagwat, A.S. (1995) A cytosine methyltransferase converts 5-methylcytosine in DNA to thymine. Biochem. 34: 14752-14757.
    • (1995) Biochem. , vol.34 , pp. 14752-14757
    • Yerba, M.J.1    Bhagwat, A.S.2
  • 17
    • 0027093283 scopus 로고
    • High frequency mutagenesis by a DNA methyltransferase
    • Shen, J.C., Rideout III, W.M. & Jones, P.A. (1992) High frequency mutagenesis by a DNA methyltransferase. Cell 71: 1073-1080.
    • (1992) Cell , vol.71 , pp. 1073-1080
    • Shen, J.C.1    Rideout W.M. III2    Jones, P.A.3
  • 19
    • 0033563083 scopus 로고    scopus 로고
    • CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression
    • Eads, C.A., Danenberg, K.D., Kawakami, K., Saltz, L.B., Danenberg, P.V. & Laird, P.W. (1999) CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression. Cancer Res. 59: 2302-2306.
    • (1999) Cancer Res. , vol.59 , pp. 2302-2306
    • Eads, C.A.1    Danenberg, K.D.2    Kawakami, K.3    Saltz, L.B.4    Danenberg, P.V.5    Laird, P.W.6
  • 20
    • 0031149098 scopus 로고    scopus 로고
    • Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat
    • Pogribny, I.P., Miller, B.J. & James, S.J. (1997) Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat. Cancer Letters 115: 31-38.
    • (1997) Cancer Letters , vol.115 , pp. 31-38
    • Pogribny, I.P.1    Miller, B.J.2    James, S.J.3
  • 21
    • 0021398869 scopus 로고
    • Effects of undermethylation on mRNA cytoplasmic appearance and half life
    • Camper, S.A., Albers, R.J., Coward, J.K. & Rottman, F.M. (1984) Effects of undermethylation on mRNA cytoplasmic appearance and half life. Mol. Cell. Biol. 4: 538-543.
    • (1984) Mol. Cell. Biol. , vol.4 , pp. 538-543
    • Camper, S.A.1    Albers, R.J.2    Coward, J.K.3    Rottman, F.M.4
  • 22
    • 0016766768 scopus 로고
    • Ethionine-induced changes in rat liver transfer RNA methylation
    • Wainfan, E., Moller, M.L., Maschio, F.A. & Balis, M.E. (1975) Ethionine-induced changes in rat liver transfer RNA methylation. Cancer Res. 35: 2830-2835.
    • (1975) Cancer Res. , vol.35 , pp. 2830-2835
    • Wainfan, E.1    Moller, M.L.2    Maschio, F.A.3    Balis, M.E.4
  • 23
    • 0343900117 scopus 로고    scopus 로고
    • Folate deficiency induces hypomethylation of the trimethylguanosine cap of small nuclear RNA in chinese hamster ovary cells: Implications for altered gene expression
    • Esfandiari, F., Moor, M.J., Paulson, E. & Mason, J.B. (1999) Folate deficiency induces hypomethylation of the trimethylguanosine cap of small nuclear RNA in Chinese hamster ovary cells: Implications for altered gene expression. Proc. Am. Ass. Cancer Res. 40: 548 A3616.
    • (1999) Proc. Am. Ass. Cancer Res. , vol.40 , pp. 548
    • Esfandiari, F.1    Moor, M.J.2    Paulson, E.3    Mason, J.B.4
  • 24
    • 0027383695 scopus 로고
    • Folate deficiency increases genetic damage caused by alkylating agents and y-irradiation in Chinese hamster ovary cells
    • Branda, R.F. & Blickensderfer, D.B. (1993) Folate deficiency increases genetic damage caused by alkylating agents and y-irradiation in Chinese hamster ovary cells. Cancer Res. 53: 5401-5408.
    • (1993) Cancer Res. , vol.53 , pp. 5401-5408
    • Branda, R.F.1    Blickensderfer, D.B.2
  • 26
    • 0031903189 scopus 로고    scopus 로고
    • Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults
    • Fenech, M., Aitken, C. & Rinaldi, J. (1998) Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults. Carcinogenesis 19: 1163-1171.
    • (1998) Carcinogenesis , vol.19 , pp. 1163-1171
    • Fenech, M.1    Aitken, C.2    Rinaldi, J.3
  • 29
    • 0031842970 scopus 로고    scopus 로고
    • Folate depletion impairs DNA excision repair in the colon of the rat
    • Choi, S.W., Kim, Y.I., Weitzel, J.N. & Mason, J.B. (1998) Folate depletion impairs DNA excision repair in the colon of the rat. Gut 43: 93-99.
    • (1998) Gut , vol.43 , pp. 93-99
    • Choi, S.W.1    Kim, Y.I.2    Weitzel, J.N.3    Mason, J.B.4
  • 30
    • 0031763502 scopus 로고    scopus 로고
    • DNA instability (strand breakage, uracil misincorporation, and defective repair) is increased by folic acid depletion in human lymphocytes in vitro
    • Duthie, S.J. & Hawdon, A. (1998) DNA instability (strand breakage, uracil misincorporation, and defective repair) is increased by folic acid depletion in human lymphocytes in vitro. FASEB J. 12: 1491-1497.
    • (1998) FASEB J. , vol.12 , pp. 1491-1497
    • Duthie, S.J.1    Hawdon, A.2
  • 32
    • 0031017268 scopus 로고    scopus 로고
    • Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
    • Kane, M.F., Loda, M., Gaida, G.M., Lipman, J., Mishra, R., Goldman, H., Jessup, J.M. & Kolodner, R. (1997) Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res. 57: 808-811.
    • (1997) Cancer Res. , vol.57 , pp. 808-811
    • Kane, M.F.1    Loda, M.2    Gaida, G.M.3    Lipman, J.4    Mishra, R.5    Goldman, H.6    Jessup, J.M.7    Kolodner, R.8
  • 34
    • 0032573077 scopus 로고    scopus 로고
    • A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells
    • Bagley, P.J. & Selhub, J. (1998) A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells. Proc. Natl. Aca. Sci. USA 95: 13217-13220.
    • (1998) Proc. Natl. Aca. Sci. USA , vol.95 , pp. 13217-13220
    • Bagley, P.J.1    Selhub, J.2
  • 35
    • 0004643258 scopus 로고    scopus 로고
    • A common polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene decreases genomic DNA methylation, but does not reduce DNA strand breaks, p53 methylation or uracil misincorporation: Implication for colorectal carcinogenesis
    • Choi, S.W., Lathrop Stern, L., Dzialo, H.M., Dolnikowski, G.G., Selhub, J. & Mason, JB. (1999) A common polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene decreases genomic DNA methylation, but does not reduce DNA strand breaks, p53 methylation or uracil misincorporation: Implication for colorectal carcinogenesis. Gastraenterology 116: A303.
    • (1999) Gastraenterology , vol.116
    • Choi, S.W.1    Lathrop Stern, L.2    Dzialo, H.M.3    Dolnikowski, G.G.4    Selhub, J.5    Mason, J.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.