The effect of folate deficiency on the cytotoxic and mutagenic responses to ethyl methanesulfonate in human lymphoblastoid cell lines that differ in p53 status

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 473, Issue 1, 2001, Pages 51-71

  Branda, Richard F ^a   O'Neill, J Patrick ^a   Brooks, Elice M ^a   Trombley, Lucy M ^a   Nicklas, Janice A ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

Alkylating agent; Folate; HPRT mutation spectrum; Human lymphoblast cells; p53

Indexed keywords

ALKYLATING AGENT; FOLIC ACID; GENE PRODUCT; MESYLIC ACID ETHYL ESTER; PROTEIN P53;

ARTICLE; BASE PAIRING; CHO CELL; CONTROLLED STUDY; CYTOTOXICITY; DNA FLANKING REGION; DOSE RESPONSE; FOLIC ACID DEFICIENCY; GENE LOCUS; GENETIC DAMAGE; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL LINE; MUTAGENICITY; MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SPLICING; SPLEEN CELL; TOXICITY;

ANTINEOPLASTIC AGENTS, ALKYLATING; BASE SEQUENCE; CELL DIVISION; CELL LINE; DNA MUTATIONAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHYL METHANESULFONATE; FOLIC ACID; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTAGENS; TUMOR SUPPRESSOR PROTEIN P53;

CRICETINAE; CRICETULUS GRISEUS;

EID: 0035945686     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(00)00138-X     Document Type: Article

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