Different effects of inorganic and dimethylated arsenic compounds on cell morphology, cytoskeletal organization, and DNA synthesis in cultured chinese hamster V79 cells

Archives of Toxicology

Volumn 72, Issue 9, 1998, Pages 566-573

  Ochi, Takafumi ^a   Nakajima, Fumie ^a   Fukumori, Nobutaka ^b  

^a TEIKYO UNIVERSITY   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

Arsenic compounds; DNA synthesis; Microtubule network; Mitotic arrest; Multinucleated cells

Indexed keywords

ANIMAL CELL; ARTICLE; CELL GROWTH; CHO CELL; CYTOPATHOGENIC EFFECT; DNA SYNTHESIS; GROWTH INHIBITION; MALE; NONHUMAN; PRIORITY JOURNAL; TOXICITY;

ANIMALS; ARSENITES; CACODYLIC ACID; CELL LINE; CELL SIZE; CRICETINAE; CRICETULUS; CYTOSKELETON; DNA; FLUORESCENT ANTIBODY TECHNIQUE; MALE; MITOSIS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0031716519     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050544     Document Type: Article

References (31)

1. Alberts B, Bray D, Lewis J, Raff M, Roberts K, Watson JD (eds) (1983) Molecular biology of the cell. Garland Press, New York, pp 549-668
2. Braman RS, Foreback CC (1973) Methylated forms of arsenic in the environment. Science 182: 1247-1249
3. Buchet JP, Lauwerys R, Roels H (1981) Comparison of the urinary excretion of arsenic metabolites after a single oral dose of sodium arsenite, monomethylarsonate or dimethylarsinate in man. Int Arch Occup Environ Health 48: 71-79
4. Caltabiano MM, Koestler TP, Poste G, Greig RG (1986) Induction of 32-and 34-kDa stress proteins by sodium arsenite, heavy metals, and thiol-reactive agents. J Biol Chem 261: 13381-13386
5. Crecelius EA (1977) Changes in the chemical speciation of arsenic following ingestion by man. Environ Health Perspect 19: 147-150
6. Da Costa EWB (1971) Suppression of the inhibitory effects of arsenic compounds by phosphate. Nature New Biol 231: 32
7. Deneke SM (1992) Induction of cystine transport in bovine pulmonary artery endothelial cells by sodium arsenite. Biochim Biophys Acta 1109: 127-131
8. Fischer AB, Buchet JP, Lauwerys RR (1985) Arsenic uptake, cytotoxicity and detoxification studies in mammalian cells in culture. Arch Toxicol 57: 168-172
9. Goyer RA (1986) Toxic effects of metals. In: Klaassen CD, Amdur MO, Doull J (eds) Casarett and Doull's toxicology. Macmillan, New York, pp 582-635
10. Hiwasa T, Sakiyama S (1986) Increase in the synthesis of a Mr 32,000 protein in BALB/c 3T3 cells after treatment with tumor promoters, chemical carcinogens, metal salts and heat shock. Cancer Res 46: 2474-2481
11. Johnston D, Oppermann H, Jackson J, Levinson W (1980) Induction of four proteins in chick embryo cells by sodium arsenite. J Biol Chem 255: 6975-6980
12. Keyse SM, Tyrell RM (1989) Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. Proc Natl Acad Sci USA 86: 99-103
13. Kuriyama R, Sakai H (1974) Role of tubulin-SH groups in polymerization to microtubules. J Biochem 76: 651-654
14. Lakso JU, Peaples SAJ (1975) Methylation of inorganic arsenic by mammals. J Agric Food Chem 23: 674-676
15. Leung MF, Chou IN (1989) Relationship between 1-chloro-2,4-dinitrobenzene-induced cytoskeletal perturbations and cellular glutathione. Cell Biol Toxicol 5: 51-66
16. Levinson W, Oppermann H, Jackson J (1980) Transition series metals and sulfhydryl reagents induce the synthesis of four proteins in eukaryotic cells. Biochim Biophys Acta 606: 170-180
17. Li W, Chou IN (1992) Effects of sodium arsenite on the cytoskeleton and cellular glutathione levels in cultured cells. Toxicol Appl Pharmacol 114: 132-139
18. Lowry OH, Rosebrough NJ, Farr NJ, Randall RJ (1951) Protein measurements with Folin phenol reagent. J Biol Chem 193: 265-275
19. Mellon M, Rebhun LI (1976) Studies on the accessible sulfhydryls of polymerizable tubulin. In: Goldman R, Pollard T, Rosenbaum J (eds) Cell motility. Cold Spring Harbor Laboratory, New York, pp 1146-1164
20. Mirabelli F, Salis A, Marinoni V, Finardi G, Bellomo G, Thor H, Orrrenius S (1988) Menadione-induced bleb formation in hepatocytes is associated with the oxidation of thiol groups in actin. Arch Biochem Biophys 264: 261-269
21. Ochi T (1997) Arsenic compound-induced increases in glutathione levels in cultured Chinese hamster V79 cells and mechanisms associated with changes in γ-glutamylcysteine synthetase activity, cystine uptake and utilization of cysteine. Arch Toxicol 71: 730-740
22. Ochi T, Kaise T, Oya-Ohta Y (1994) Glutathione plays different roles in the induction of the cytotoxic effects of inorganic and organic arsenic compounds in cultured BALB/c 3T3 cells. Experientia 50: 115-120
23. Ochi T, Nakajima F, Sakurai T, Kaise T, Oya-Ohta Y (1996) Dimethylarsinic acid causes apoptosis in HL-60 cells via interaction with glutathione. Arch Toxicol 70: 815-821
24. Oppenheim JJ, Fischbein WN (1965) Induction of chromosome breaks in cultured normal human leukocytes by potassium arsenite, hydroxyurea and related compounds. Cancer Res 25: 980-985
25. Oya-Ohta Y, Kaise T, Ochi T (1996) Induction of chromosomal aberrations in cultured human fibroblasts by inorganic and organic arsenic compounds and the different roles of glutathione in such induction. Mutat Res 357: 123-129
26. Petres J, Baron D, Hagedorn M (1977) Effects of arsenic on cell metabolism and cell proliferation. Cytogenetic and biochemical studies. Environ Health Perspect 19: 223-227
27. Rossman TG, Meyn MS, Troll W (1977) Effects of arsenite on DNA repair in Excherichia coli. Environ Health Perspect 19: 229-233
28. 32P into nucleic acids of lymphatic cells. Exp Cell Res 17: 131-143
29. 74As. Anal Biochem 86: 505-511
30. Vahter M (1981) Biotransformation of trivalent and pentavalent inorganic arsenic in mice and rats. Environ Res 25: 286-293
31. Vallee BL, Ulmer DD, Wacker WEC (1960) Arsenic toxicology and biochemistry. AMA Arch Ind Health 21: 132-151