-
1
-
-
0028883828
-
Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
-
for the West of Scotland Coronary Prevention Study Group
-
Shepherd J, Cobbe SM, Ford I, Isles CG, Lorimer AR, MacFarlane PW, McKillop JH, Packard CJ, for the West of Scotland Coronary Prevention Study Group. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med 1995;333:1301-7.
-
(1995)
N Engl J Med
, vol.333
, pp. 1301-1307
-
-
Shepherd, J.1
Cobbe, S.M.2
Ford, I.3
Isles, C.G.4
Lorimer, A.R.5
MacFarlane, P.W.6
McKillop, J.H.7
Packard, C.J.8
-
2
-
-
0037840242
-
-
Collins R, Armitage J, Parish S, Sleigh P, Peto R. MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet 2003;361:2005-16.
-
Collins R, Armitage J, Parish S, Sleigh P, Peto R. MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet 2003;361:2005-16.
-
-
-
-
3
-
-
0036231636
-
Clinical efficacy of pitavastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in patients with hyperlipidemia. Dose-finding study using the double-blind, three-group parallel comparison
-
Saito Y, Yamada N, Teramoto T, Itakura H, Hata Y, Nakaya N, Mabuchi H, Tushima M, Sasaki J, Goto Y, Ogawa N. Clinical efficacy of pitavastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, in patients with hyperlipidemia. Dose-finding study using the double-blind, three-group parallel comparison. Arzneimittelforschung 2002;52:251-5.
-
(2002)
Arzneimittelforschung
, vol.52
, pp. 251-255
-
-
Saito, Y.1
Yamada, N.2
Teramoto, T.3
Itakura, H.4
Hata, Y.5
Nakaya, N.6
Mabuchi, H.7
Tushima, M.8
Sasaki, J.9
Goto, Y.10
Ogawa, N.11
-
4
-
-
0036804450
-
Factors affecting low-density lipoprotein and high-density lipoprotein cholesterol response to pravastatin in the West of Scotland Coronary Prevention Study (WOSCOPS)
-
Streja L, Packard CJ, Shepherd J, Cobbe S, Ford I. Factors affecting low-density lipoprotein and high-density lipoprotein cholesterol response to pravastatin in the West of Scotland Coronary Prevention Study (WOSCOPS). Am J Cardiol 2002;90:731-6.
-
(2002)
Am J Cardiol
, vol.90
, pp. 731-736
-
-
Streja, L.1
Packard, C.J.2
Shepherd, J.3
Cobbe, S.4
Ford, I.5
-
5
-
-
0034638746
-
Statins and the risk of dementia
-
Jick H, Zornberg GL, Jick SS, Seshadri S, Drachman DA. Statins and the risk of dementia. Lancet 2000;356:1627-31.
-
(2000)
Lancet
, vol.356
, pp. 1627-1631
-
-
Jick, H.1
Zornberg, G.L.2
Jick, S.S.3
Seshadri, S.4
Drachman, D.A.5
-
6
-
-
33745764469
-
The role of pleiotropic effects of statins in dementia
-
Crisby M. The role of pleiotropic effects of statins in dementia. Acta Neurol Scand Suppl 2006;185:115-18.
-
(2006)
Acta Neurol Scand Suppl
, vol.185
, pp. 115-118
-
-
Crisby, M.1
-
7
-
-
0034725352
-
HMG-CoA reductase inhibitors and the risk of fractures
-
Meier CR, Schlienger RG, Kraenzlin ME, Schlegel B, Jick H. HMG-CoA reductase inhibitors and the risk of fractures. JAMA 2000;283:3205-10.
-
(2000)
JAMA
, vol.283
, pp. 3205-3210
-
-
Meier, C.R.1
Schlienger, R.G.2
Kraenzlin, M.E.3
Schlegel, B.4
Jick, H.5
-
8
-
-
7544219925
-
Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer
-
Graaf MR, Richel DJ, van Noorden CJ, Guchelaar HJ. Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer. Cancer Treat Rev 2004;30:609-41.
-
(2004)
Cancer Treat Rev
, vol.30
, pp. 609-641
-
-
Graaf, M.R.1
Richel, D.J.2
van Noorden, C.J.3
Guchelaar, H.J.4
-
10
-
-
2542458153
-
Potential antitumor effects of statins
-
Jakobisiak M, Golab J. Potential antitumor effects of statins. Int J Oncol 2003;23:1055-69.
-
(2003)
Int J Oncol
, vol.23
, pp. 1055-1069
-
-
Jakobisiak, M.1
Golab, J.2
-
11
-
-
33749040295
-
Breast cancer growth prevention by statins
-
Campbell MJ, Esserman LJ, Zhou Y, Shoemaker M, Lobo M, Borman E, Baehner F, Kumar AS, Adduci K, Marx C, Petricoin EF, Liotta LA, et al. Breast cancer growth prevention by statins. Cancer Res 2006;66:8707-14.
-
(2006)
Cancer Res
, vol.66
, pp. 8707-8714
-
-
Campbell, M.J.1
Esserman, L.J.2
Zhou, Y.3
Shoemaker, M.4
Lobo, M.5
Borman, E.6
Baehner, F.7
Kumar, A.S.8
Adduci, K.9
Marx, C.10
Petricoin, E.F.11
Liotta, L.A.12
-
12
-
-
28844490054
-
Statins and cancer prevention
-
Demierre MF, Higgins PD, Gruber SB, Hawk E, Lippman SM. Statins and cancer prevention. Nat Rev Cancer 2005;5:930-42.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 930-942
-
-
Demierre, M.F.1
Higgins, P.D.2
Gruber, S.B.3
Hawk, E.4
Lippman, S.M.5
-
13
-
-
0027978838
-
Prevention of 1,2-dimethylhydrazine-induced colon tumorigenesis by HMG-CoA reductase inhibitors, pravastatin and simvastatin, in ICR mice
-
Narisawa T, Fukaura Y, Terada K, Umezawa A, Tanida N, Yazawa K, Ishikawa C. Prevention of 1,2-dimethylhydrazine-induced colon tumorigenesis by HMG-CoA reductase inhibitors, pravastatin and simvastatin, in ICR mice. Carcinogenesis 1994;15:2045-8.
-
(1994)
Carcinogenesis
, vol.15
, pp. 2045-2048
-
-
Narisawa, T.1
Fukaura, Y.2
Terada, K.3
Umezawa, A.4
Tanida, N.5
Yazawa, K.6
Ishikawa, C.7
-
14
-
-
0029815533
-
Chemoprevention by pravastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, of N-methyl-N-nitrosourea-induced colon carcinogenesis in F344 rats
-
Narisawa T, Morotomi M, Fukaura Y, Hasebe M, Ito M, Aizawa R. Chemoprevention by pravastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, of N-methyl-N-nitrosourea-induced colon carcinogenesis in F344 rats. Jpn J Cancer Res 1996;87:798-804.
-
(1996)
Jpn J Cancer Res
, vol.87
, pp. 798-804
-
-
Narisawa, T.1
Morotomi, M.2
Fukaura, Y.3
Hasebe, M.4
Ito, M.5
Aizawa, R.6
-
15
-
-
33646240343
-
Prevention of azoxymethane-induced colon cancer by combination of low doses of atorvastatin, aspirin, and celecoxib in F 344 rats
-
Reddy BS, Wang CX, Kong AN, Khor TO, Zheng X, Steele VE, Kopelovich L, Rao CV. Prevention of azoxymethane-induced colon cancer by combination of low doses of atorvastatin, aspirin, and celecoxib in F 344 rats. Cancer Res 2006;66:4542-6.
-
(2006)
Cancer Res
, vol.66
, pp. 4542-4546
-
-
Reddy, B.S.1
Wang, C.X.2
Kong, A.N.3
Khor, T.O.4
Zheng, X.5
Steele, V.E.6
Kopelovich, L.7
Rao, C.V.8
-
16
-
-
33746872856
-
Chemoprevention of familial adenomatous polyposis by low doses of atorvastatin and celecoxib given individually and in combination to APCMin mice
-
Swamy MV, Patlolla JM, Steele VE, Kopelovich L, Reddy BS, Rao CV. Chemoprevention of familial adenomatous polyposis by low doses of atorvastatin and celecoxib given individually and in combination to APCMin mice. Cancer Res 2006;66:7370-7.
-
(2006)
Cancer Res
, vol.66
, pp. 7370-7377
-
-
Swamy, M.V.1
Patlolla, J.M.2
Steele, V.E.3
Kopelovich, L.4
Reddy, B.S.5
Rao, C.V.6
-
17
-
-
9344256068
-
Simvastatin prevents vascular hyporeactivity during inflammation
-
Pleiner J, Schaller G, Mittermayer F, Zorn S, Marsik C, Polterauer S, Kapiotis S, Wolzt M. Simvastatin prevents vascular hyporeactivity during inflammation. Circulation 2004;110:3349-54.
-
(2004)
Circulation
, vol.110
, pp. 3349-3354
-
-
Pleiner, J.1
Schaller, G.2
Mittermayer, F.3
Zorn, S.4
Marsik, C.5
Polterauer, S.6
Kapiotis, S.7
Wolzt, M.8
-
18
-
-
0035901090
-
Inflammation and cancer: Back to Virchow?
-
Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet 200I;357:539-45.
-
Lancet
, vol.200 I
, Issue.357
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
19
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860-7.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
20
-
-
10744221150
-
Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis
-
Rutter M, Saunders B, Wilkinson K, Rumbles S, Schofield G, Kamm M, Williams C, Price A, Talbot I, Forbes A. Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis. Gastroenterology 2004;126:451-9.
-
(2004)
Gastroenterology
, vol.126
, pp. 451-459
-
-
Rutter, M.1
Saunders, B.2
Wilkinson, K.3
Rumbles, S.4
Schofield, G.5
Kamm, M.6
Williams, C.7
Price, A.8
Talbot, I.9
Forbes, A.10
-
21
-
-
0035080617
-
The risk of colorectal cancer in ulcerative colitis: A meta-analysis
-
Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut 2001;48:526-35.
-
(2001)
Gut
, vol.48
, pp. 526-535
-
-
Eaden, J.A.1
Abrams, K.R.2
Mayberry, J.F.3
-
22
-
-
0344237231
-
A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate
-
Tanaka T, Kohno H, Suzuki R, Yamada Y, Sugie S, Mori H. A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate. Cancer Sci 2003;94:965-73.
-
(2003)
Cancer Sci
, vol.94
, pp. 965-973
-
-
Tanaka, T.1
Kohno, H.2
Suzuki, R.3
Yamada, Y.4
Sugie, S.5
Mori, H.6
-
23
-
-
33646401129
-
Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis-related colon carcinogenesis in mice
-
Kohno H, Suzuki R, Curini M, Epifano F, Maltese F, Gonzales SP, Tanaka T. Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis-related colon carcinogenesis in mice. Int J Cancer 2006;118:2936-42.
-
(2006)
Int J Cancer
, vol.118
, pp. 2936-2942
-
-
Kohno, H.1
Suzuki, R.2
Curini, M.3
Epifano, F.4
Maltese, F.5
Gonzales, S.P.6
Tanaka, T.7
-
24
-
-
33746909830
-
Lack of enhancing effects of degraded λ-carrageenan on the development of β-catenin-aecumulated crypts in male DBA/2J mice initiated with azoxymethane
-
Hata K, Tanaka T, Kohno H, Suzuki R, Qiang SH, Kuno T, Hirose Y, Hara A, Mori H. Lack of enhancing effects of degraded λ-carrageenan on the development of β-catenin-aecumulated crypts in male DBA/2J mice initiated with azoxymethane. Cancer Lett 2006;238:69-75.
-
(2006)
Cancer Lett
, vol.238
, pp. 69-75
-
-
Hata, K.1
Tanaka, T.2
Kohno, H.3
Suzuki, R.4
Qiang, S.H.5
Kuno, T.6
Hirose, Y.7
Hara, A.8
Mori, H.9
-
25
-
-
14744302105
-
-
Mukhtar RY, Reid J, Reckless JP. Pitavastatin. Int J Clin Pract 2005;59:239-4.
-
Mukhtar RY, Reid J, Reckless JP. Pitavastatin. Int J Clin Pract 2005;59:239-4.
-
-
-
-
27
-
-
0036234655
-
A randomized, double-blind trial comparing the efficacy and safety of pitavastatin versus pravastatin in patients with primary hypercholesterolemia
-
Saito Y, Yamada N, Teramoto T, Itakura H, Hata Y, Nakaya N, Mabuchi H, Tushima M, Sasaki J, Ogawa N, Goto Y. A randomized, double-blind trial comparing the efficacy and safety of pitavastatin versus pravastatin in patients with primary hypercholesterolemia. Atherosclerosis 2002;162:373-9.
-
(2002)
Atherosclerosis
, vol.162
, pp. 373-379
-
-
Saito, Y.1
Yamada, N.2
Teramoto, T.3
Itakura, H.4
Hata, Y.5
Nakaya, N.6
Mabuchi, H.7
Tushima, M.8
Sasaki, J.9
Ogawa, N.10
Goto, Y.11
-
28
-
-
10744230409
-
New drugs for the treatment of hypercholesterolaemia
-
Iglesias P, Diez JJ. New drugs for the treatment of hypercholesterolaemia. Expert Opin Investig Drugs 2003;12:1777-89.
-
(2003)
Expert Opin Investig Drugs
, vol.12
, pp. 1777-1789
-
-
Iglesias, P.1
Diez, J.J.2
-
29
-
-
0141988934
-
Pitavastatin: Efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor
-
Kajinami K, Takekoshi N, Saito Y. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor. Cardiovasc Drug Rev 2003;21:199-215.
-
(2003)
Cardiovasc Drug Rev
, vol.21
, pp. 199-215
-
-
Kajinami, K.1
Takekoshi, N.2
Saito, Y.3
-
30
-
-
17344385356
-
The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC. Human umbilical vein endothelial cells
-
Morikawa S, Takabe W, Mataki C, Kanke T, Itoh T, Wada Y, Izumi A, Saito Y, Hamakubo T, Kodama T. The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC. Human umbilical vein endothelial cells. J Atheroscler Thromb 2002;9:178-3.
-
(2002)
J Atheroscler Thromb
, vol.9
, pp. 178-173
-
-
Morikawa, S.1
Takabe, W.2
Mataki, C.3
Kanke, T.4
Itoh, T.5
Wada, Y.6
Izumi, A.7
Saito, Y.8
Hamakubo, T.9
Kodama, T.10
-
31
-
-
33748139379
-
Chemoprevention: Risk reduction with medical therapy of inflammatory bowel disease
-
Chan EP, Lichtenstein GR. Chemoprevention: risk reduction with medical therapy of inflammatory bowel disease. Gastroenterol Clin North Am 2006;35:675-712.
-
(2006)
Gastroenterol Clin North Am
, vol.35
, pp. 675-712
-
-
Chan, E.P.1
Lichtenstein, G.R.2
-
32
-
-
33745491465
-
Concomitant suppression of hyperlipidemia and intestinal polyp formation by increasing lipoprotein lipase activity in Ape-deficient mice
-
Mutoh M, Niho N, Wakabayashi K. Concomitant suppression of hyperlipidemia and intestinal polyp formation by increasing lipoprotein lipase activity in Ape-deficient mice. Biol Chem 2006;387:381-5.
-
(2006)
Biol Chem
, vol.387
, pp. 381-385
-
-
Mutoh, M.1
Niho, N.2
Wakabayashi, K.3
-
33
-
-
0027224059
-
Clinicopathologic study of dextran sulfate sodium experimental murine colitis
-
Cooper HS, Murthy SN, Shah RS, Sedergran DJ. Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 1993;69:238-49.
-
(1993)
Lab Invest
, vol.69
, pp. 238-249
-
-
Cooper, H.S.1
Murthy, S.N.2
Shah, R.S.3
Sedergran, D.J.4
-
36
-
-
0037322961
-
Modulation of the inflammatory process by statins
-
Crisby M. Modulation of the inflammatory process by statins. Drugs Today (Barc) 2003;39:137-43.
-
(2003)
Drugs Today (Barc)
, vol.39
, pp. 137-143
-
-
Crisby, M.1
-
38
-
-
33845943499
-
Simvastatin inhibits NF-κB signaling in intestinal epithelial cells and ameliorates acute murine colitis
-
Lee JY, Kim JS, Kim JM, Kim N, Jung HC, Song IS. Simvastatin inhibits NF-κB signaling in intestinal epithelial cells and ameliorates acute murine colitis. Im Immunopharmacol 2007;7:241-8.
-
(2007)
Im Immunopharmacol
, vol.7
, pp. 241-248
-
-
Lee, J.Y.1
Kim, J.S.2
Kim, J.M.3
Kim, N.4
Jung, H.C.5
Song, I.S.6
-
39
-
-
33745727522
-
Rosuvastatin, a new HMG-CoA reductase inhibitor, reduces the colonic inflammatory response in dextran sulfate sodium-induced colitis in mice
-
Naito Y, Katada K, Takagi T, Tsuboi H, Isozaki Y, Handa O, Kokura S, Yoshida N, Ichikawa H, Yoshikawa T. Rosuvastatin, a new HMG-CoA reductase inhibitor, reduces the colonic inflammatory response in dextran sulfate sodium-induced colitis in mice. Int J Mol Med 2006;17:997-1004.
-
(2006)
Int J Mol Med
, vol.17
, pp. 997-1004
-
-
Naito, Y.1
Katada, K.2
Takagi, T.3
Tsuboi, H.4
Isozaki, Y.5
Handa, O.6
Kokura, S.7
Yoshida, N.8
Ichikawa, H.9
Yoshikawa, T.10
-
40
-
-
33745505400
-
Pitavastatin-induced down-regulation of CCR2 and CCR5 in monocytes is associated with the arrest of cell-cycle in S phase
-
Fujino M, Miura S, Matsuo Y, Tanigawa H, Kawamura A, Saku K. Pitavastatin-induced down-regulation of CCR2 and CCR5 in monocytes is associated with the arrest of cell-cycle in S phase. Atherosclerosis 2006;187:301-8.
-
(2006)
Atherosclerosis
, vol.187
, pp. 301-308
-
-
Fujino, M.1
Miura, S.2
Matsuo, Y.3
Tanigawa, H.4
Kawamura, A.5
Saku, K.6
-
41
-
-
2142822265
-
Chemokines in inflammatory bowel disease
-
Papadakis KA. Chemokines in inflammatory bowel disease. Curr Allergy Asthma Rep 2004;4:83-9.
-
(2004)
Curr Allergy Asthma Rep
, vol.4
, pp. 83-89
-
-
Papadakis, K.A.1
-
42
-
-
14144256390
-
Pitavastatin at low dose activates endothelial nitric oxide synthase through PI3K-AKT pathway in endothelial cells
-
Wang J, Tokoro T, Matsui K, Higa S, Kitajima I. Pitavastatin at low dose activates endothelial nitric oxide synthase through PI3K-AKT pathway in endothelial cells. Life Sci 2005;76:2257-68.
-
(2005)
Life Sci
, vol.76
, pp. 2257-2268
-
-
Wang, J.1
Tokoro, T.2
Matsui, K.3
Higa, S.4
Kitajima, I.5
-
43
-
-
14344259226
-
Leukocytes on the move with phosphoinositide 3-kinase and its downstream effectors
-
Procko E, McColl SR. Leukocytes on the move with phosphoinositide 3-kinase and its downstream effectors. Bioessays 2005;27:153-63.
-
(2005)
Bioessays
, vol.27
, pp. 153-163
-
-
Procko, E.1
McColl, S.R.2
-
44
-
-
0035902180
-
Oncogenic kinase signalling
-
Blume-Jensen P, Hunter T. Oncogenic kinase signalling. Nature 2001;411:355-65.
-
(2001)
Nature
, vol.411
, pp. 355-365
-
-
Blume-Jensen, P.1
Hunter, T.2
-
45
-
-
0142227019
-
Targeting the PI3K-Akt pathway in human cancer: Rationale and promise
-
Luo J, Manning BD, Cantley LC. Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell 2003;4:257-62.
-
(2003)
Cancer Cell
, vol.4
, pp. 257-262
-
-
Luo, J.1
Manning, B.D.2
Cantley, L.C.3
-
46
-
-
33745325973
-
Targeted molecular therapy of the PI3K pathway: Therapeutic significance of PI3K subunit targeting in colorectal carcinoma
-
Rychahou PG, Jackson LN, Silva SR, Rajaraman S, Evers BM. Targeted molecular therapy of the PI3K pathway: therapeutic significance of PI3K subunit targeting in colorectal carcinoma. Ann Surg 2006;243:833-42.
-
(2006)
Ann Surg
, vol.243
, pp. 833-842
-
-
Rychahou, P.G.1
Jackson, L.N.2
Silva, S.R.3
Rajaraman, S.4
Evers, B.M.5
-
47
-
-
0037299903
-
Suppression of pro-inflammatory cytokine release by selective inhibition of inducible nitric oxide synthase in mucosal explants from patients with ulcerative colitis
-
Kankuri E, Hamalainen M, Hukkanen M, Salmenpera P, Kivilaakso E, Vapaatalo H, Moilanen E. Suppression of pro-inflammatory cytokine release by selective inhibition of inducible nitric oxide synthase in mucosal explants from patients with ulcerative colitis. Scand J Gastroenterol 2003;38:186-92.
-
(2003)
Scand J Gastroenterol
, vol.38
, pp. 186-192
-
-
Kankuri, E.1
Hamalainen, M.2
Hukkanen, M.3
Salmenpera, P.4
Kivilaakso, E.5
Vapaatalo, H.6
Moilanen, E.7
-
48
-
-
0031567576
-
What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo?
-
Halliwell B. What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo? FEBS Lett 1997;411:157-60.
-
(1997)
FEBS Lett
, vol.411
, pp. 157-160
-
-
Halliwell, B.1
-
49
-
-
0031984809
-
Frequent nitric oxide synthase-2 expression in human colon adenomas: Implication for tumor angiogenesis and colon cancer progression
-
Ambs S, Merriam WG, Bennett WP, Felley-Bosco E, Ogunfusika MO, Oser SM, Klein S, Shields PG, Billiar TR, Harris CC. Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression. Cancer Res 1998;58:334-41.
-
(1998)
Cancer Res
, vol.58
, pp. 334-341
-
-
Ambs, S.1
Merriam, W.G.2
Bennett, W.P.3
Felley-Bosco, E.4
Ogunfusika, M.O.5
Oser, S.M.6
Klein, S.7
Shields, P.G.8
Billiar, T.R.9
Harris, C.C.10
-
50
-
-
0033924401
-
Altered expression of β-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis
-
Takahashi M, Mutoh M, Kawamori T, Sugimura T, Wakabayashi K. Altered expression of β-catenin, inducible nitric oxide synthase and cyclooxygenase-2 in azoxymethane-induced rat colon carcinogenesis. Carcinogenesis 2000;21:1319-27.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1319-1327
-
-
Takahashi, M.1
Mutoh, M.2
Kawamori, T.3
Sugimura, T.4
Wakabayashi, K.5
-
51
-
-
0030615201
-
-
Barnes PJ, Karin M. Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997;336:1066-71.
-
Barnes PJ, Karin M. Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997;336:1066-71.
-
-
-
-
52
-
-
0033621956
-
The Rel/NF-κB family directly activates expression of the apoptosis inhibitor Bcl-x(L)
-
Chen C, Edelstein LC, Gelinas C. The Rel/NF-κB family directly activates expression of the apoptosis inhibitor Bcl-x(L). Mol Cell Biol 2000;20:2687-95.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2687-2695
-
-
Chen, C.1
Edelstein, L.C.2
Gelinas, C.3
-
53
-
-
0033596127
-
Control of apoptosis by Rel/NF-κB transcription factors
-
Barkett M, Gilmore TD. Control of apoptosis by Rel/NF-κB transcription factors. Oncogene 1999;18:6910-24.
-
(1999)
Oncogene
, vol.18
, pp. 6910-6924
-
-
Barkett, M.1
Gilmore, T.D.2
-
54
-
-
33645537284
-
Anti-inflammatory effect of pitavastatin on NF-κB activated by TNF-α in hepatocellular carcinoma cells
-
Wang J, Tokoro T, Higa S, Kitajima I. Anti-inflammatory effect of pitavastatin on NF-κB activated by TNF-α in hepatocellular carcinoma cells. Biol Pharm Bull 2006;29:634-9.
-
(2006)
Biol Pharm Bull
, vol.29
, pp. 634-639
-
-
Wang, J.1
Tokoro, T.2
Higa, S.3
Kitajima, I.4
-
55
-
-
0043095361
-
Intracellular IL-IRa type 1 inhibits IL-1-induced IL-6 and IL-8 production in Caco-2 intestinal epithelial cells through inhibition of p38 mitogen-activated protein kinase and NF-κB pathways
-
Garat C, Arend WP. Intracellular IL-IRa type 1 inhibits IL-1-induced IL-6 and IL-8 production in Caco-2 intestinal epithelial cells through inhibition of p38 mitogen-activated protein kinase and NF-κB pathways. Cytokine 2003;23:31-40.
-
(2003)
Cytokine
, vol.23
, pp. 31-40
-
-
Garat, C.1
Arend, W.P.2
-
56
-
-
20444500117
-
Inhibitory effect of pitavastatin (NK-104) on the C-reactive-protein-induced interleukin-8 production in human aortic endothelial cells
-
Kibayashi E, Urakaze M, Kobashi C, Kishida M, Takata M, Sato A, Yamazaki K, Kobayashi M. Inhibitory effect of pitavastatin (NK-104) on the C-reactive-protein-induced interleukin-8 production in human aortic endothelial cells. Clin Sci (Lond) 2005;108:515-21.
-
(2005)
Clin Sci (Lond)
, vol.108
, pp. 515-521
-
-
Kibayashi, E.1
Urakaze, M.2
Kobashi, C.3
Kishida, M.4
Takata, M.5
Sato, A.6
Yamazaki, K.7
Kobayashi, M.8
-
57
-
-
0037342590
-
Pitavastatin-induced thrombomodulin expression by endothelial cells acts via inhibition of small G proteins of the Rho family
-
Masamura K, Oida K, Kanehara H, Suzuki J, Horie S, Ishii H, Miyamori I. Pitavastatin-induced thrombomodulin expression by endothelial cells acts via inhibition of small G proteins of the Rho family. Arterioscler Thromb Vasc Biol 2003;23:512-17.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 512-517
-
-
Masamura, K.1
Oida, K.2
Kanehara, H.3
Suzuki, J.4
Horie, S.5
Ishii, H.6
Miyamori, I.7
-
58
-
-
17044448335
-
Mechanisms of action of statins and their pleiotropic effects (in French)
-
Davignon J, Mabile L. Mechanisms of action of statins and their pleiotropic effects (in French). Ann Endocrinol (Paris) 2001;62 (Part 2):101-12.
-
(2001)
Ann Endocrinol (Paris)
, vol.62
, Issue.PART 2
, pp. 101-112
-
-
Davignon, J.1
Mabile, L.2
-
59
-
-
0032766426
-
Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells
-
Agarwal B, Bhendwal S, Halmos B, Moss SF, Ramey WG, Holt PR. Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells. Clin Cancer Res 1999;5:2223-9.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2223-2229
-
-
Agarwal, B.1
Bhendwal, S.2
Halmos, B.3
Moss, S.F.4
Ramey, W.G.5
Holt, P.R.6
-
60
-
-
19844367157
-
Statins activate the mitochondrial pathway of apoptosis in human lymphoblasts and myeloma cells
-
Cafforio P, Dammacco F, Gernone A, Silvestris F. Statins activate the mitochondrial pathway of apoptosis in human lymphoblasts and myeloma cells. Carcinogenesis 2005;26:883-91.
-
(2005)
Carcinogenesis
, vol.26
, pp. 883-891
-
-
Cafforio, P.1
Dammacco, F.2
Gernone, A.3
Silvestris, F.4
-
61
-
-
0031963951
-
Caspase-7 is activated during lovastatin-induced apoptosis of the prostate cancer cell line LNCaP
-
Marcelli M, Cunningham GR, Haidacher SJ, Padayatty SJ, Sturgis L, Kagan C, Denner L. Caspase-7 is activated during lovastatin-induced apoptosis of the prostate cancer cell line LNCaP. Cancer Res 1998;58:76-83.
-
(1998)
Cancer Res
, vol.58
, pp. 76-83
-
-
Marcelli, M.1
Cunningham, G.R.2
Haidacher, S.J.3
Padayatty, S.J.4
Sturgis, L.5
Kagan, C.6
Denner, L.7
-
62
-
-
0033982224
-
Induction of apoptosis by lovastatin through activation of caspase-3 and DNase II in leukaemia HL-60 cells
-
Wang IK, Lin-Shiau SY, Lin JK. Induction of apoptosis by lovastatin through activation of caspase-3 and DNase II in leukaemia HL-60 cells. Pharmacol Toxicol 2000;86:83-91.
-
(2000)
Pharmacol Toxicol
, vol.86
, pp. 83-91
-
-
Wang, I.K.1
Lin-Shiau, S.Y.2
Lin, J.K.3
-
63
-
-
32444440805
-
Apoptosis of rheumatoid synovial cells by statins through the blocking of protein geranylgeranylation: A potential therapeutic approach to rheumatoid arthritis
-
Nagashima T, Okazaki H, Yudoh K, Matsuno H, Minota S. Apoptosis of rheumatoid synovial cells by statins through the blocking of protein geranylgeranylation: a potential therapeutic approach to rheumatoid arthritis. Arthritis Rheum 2006;54:579-86.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 579-586
-
-
Nagashima, T.1
Okazaki, H.2
Yudoh, K.3
Matsuno, H.4
Minota, S.5
-
64
-
-
33750614511
-
A therapeutic dose of the lipophilic statin pitavastatin enhances oxidant-induced apoptosis in human vascular smooth muscle cells
-
Tsujimoto A, Takemura G, Mikami A, Aoyama T, Ohno T, Maruyama R, Nakagawa M, Minatoguchi S, Fujiwara H. A therapeutic dose of the lipophilic statin pitavastatin enhances oxidant-induced apoptosis in human vascular smooth muscle cells. J Cardiovasc Pharmacol 2006;48:160-5.
-
(2006)
J Cardiovasc Pharmacol
, vol.48
, pp. 160-165
-
-
Tsujimoto, A.1
Takemura, G.2
Mikami, A.3
Aoyama, T.4
Ohno, T.5
Maruyama, R.6
Nakagawa, M.7
Minatoguchi, S.8
Fujiwara, H.9
-
65
-
-
33749577598
-
Differential efficacy of 3-hydroxy-3-methylglutaryl CoA reductase inhibitors on the cell cycle of prostate cancer cells
-
Sivaprasad U, Abbas T, Dutta A. Differential efficacy of 3-hydroxy-3-methylglutaryl CoA reductase inhibitors on the cell cycle of prostate cancer cells. Mol Cancer Ther 2006;5:2310-16.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2310-2316
-
-
Sivaprasad, U.1
Abbas, T.2
Dutta, A.3
-
67
-
-
33645522099
-
Hypertriglyceridemia is positively correlated with the development of colorectal tubular adenoma in Japanese men
-
Tabuchi M, Kitayama J, Nagawa H. Hypertriglyceridemia is positively correlated with the development of colorectal tubular adenoma in Japanese men. World J Gastroenterol 2006;12:1261-4.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 1261-1264
-
-
Tabuchi, M.1
Kitayama, J.2
Nagawa, H.3
-
68
-
-
0031730011
-
Relation of serum total cholesterol, serum triglycerides and fasting plasma glucose to colorectal carcinoma in situ
-
Yamada K, Araki S, Tamura M, Sakai I, Takahashi Y, Kashihara H, Kono S. Relation of serum total cholesterol, serum triglycerides and fasting plasma glucose to colorectal carcinoma in situ. Int J Epidemiol 1998;27:794-8.
-
(1998)
Int J Epidemiol
, vol.27
, pp. 794-798
-
-
Yamada, K.1
Araki, S.2
Tamura, M.3
Sakai, I.4
Takahashi, Y.5
Kashihara, H.6
Kono, S.7
-
69
-
-
33645866760
-
Possible involvement of hyperlipidemia in increasing risk of colorectal tumor development in human familial adenomatous polyposis
-
Mutoh M, Akasu T, Takahashi M, Niho N, Yoshida T, Sugimura T, Wakabayashi K. Possible involvement of hyperlipidemia in increasing risk of colorectal tumor development in human familial adenomatous polyposis. Jpn J Clin Oncol 2006;36:166-71.
-
(2006)
Jpn J Clin Oncol
, vol.36
, pp. 166-171
-
-
Mutoh, M.1
Akasu, T.2
Takahashi, M.3
Niho, N.4
Yoshida, T.5
Sugimura, T.6
Wakabayashi, K.7
-
70
-
-
33750804476
-
Impact of lipoprotein lipase gene polymorphisms on ulcerative colitis
-
Kosaka T, Yoshino J, Inui K, Wakabayashi T, Okushima K, Kobayashi T, Miyoshi H, Nakamura Y, Hayashi S, Shiraishi T, Watanabe M, Yamamoto T et al. Impact of lipoprotein lipase gene polymorphisms on ulcerative colitis. World J Gastroenterol 2006;12:6325-30.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 6325-6330
-
-
Kosaka, T.1
Yoshino, J.2
Inui, K.3
Wakabayashi, T.4
Okushima, K.5
Kobayashi, T.6
Miyoshi, H.7
Nakamura, Y.8
Hayashi, S.9
Shiraishi, T.10
Watanabe, M.11
Yamamoto, T.12
-
71
-
-
0036895605
-
Cancer prevention in patients with inflammatory bowel disease
-
Itzkowitz SH. Cancer prevention in patients with inflammatory bowel disease. Gastroenterol Clin North Am 2002;31:1133-44.
-
(2002)
Gastroenterol Clin North Am
, vol.31
, pp. 1133-1144
-
-
Itzkowitz, S.H.1
-
72
-
-
33744955457
-
Colorectal cancer in inflammatory bowel disease: Molecular and clinical considerations
-
Rubin DT, Parekh N. Colorectal cancer in inflammatory bowel disease: molecular and clinical considerations. Curr Treat Options Gastroenterol 2006;9:211-20.
-
(2006)
Curr Treat Options Gastroenterol
, vol.9
, pp. 211-220
-
-
Rubin, D.T.1
Parekh, N.2
|