Inhibitory effect of pitavastatin (NK-104) on the C-reactive-protein- induced interleukin-8 production in human aortic endothelial cells

Clinical Science

Volumn 108, Issue 6, 2005, Pages 515-521

  Kibayashi, Etsuko ^a,b   Urakaze, Masaharu ^a   Kobashi, Chikaaki ^a   Kishida, Mika ^a   Takata, Michiyo ^a   Sato, Akira ^a   Yamazaki, Katsuya ^a   Kobayashi, Masashi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b Sonoda Women's University   (Japan)

Author keywords

Aortic endothelial cell; Atherosclerosis; C reactive protein; Inflammation; Interleukin 8; Mitogen activated protein kinase; Statin

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALPHA CHEMOKINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; C REACTIVE PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PITAVASTATIN; STRESS ACTIVATED PROTEIN KINASE;

ANTIINFLAMMATORY ACTIVITY; AORTA; ARTICLE; ATHEROSCLEROSIS; CELL ADHESION; CHOLESTEROL BLOOD LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MONOCYTE; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; AORTA; ARTERIOSCLEROSIS; BLOTTING, NORTHERN; BLOTTING, WESTERN; C-REACTIVE PROTEIN; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INTERLEUKIN-8; QUINOLINES;

EID: 20444500117     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20040315     Document Type: Article

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