-
1
-
-
0029968460
-
Trinucleotide repeats in neurogenetic disorders
-
Paulson HL, Fischbeck KH (1996) Trinucleotide repeats in neurogenetic disorders. Annu Rev Neurosci 19: 79-107.
-
(1996)
Annu Rev Neurosci
, vol.19
, pp. 79-107
-
-
Paulson, H.L.1
Fischbeck, K.H.2
-
2
-
-
23844525922
-
Huntington's disease genetics
-
Myers RH (2004) Huntington's disease genetics. NeuroRx 1: 255-262.
-
(2004)
NeuroRx
, vol.1
, pp. 255-262
-
-
Myers, R.H.1
-
3
-
-
0029055601
-
Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form
-
Trottier Y, Devys D, Imbert G, Saudou F, An I, et al. (1995) Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form. Nat Genet 10: 104-110.
-
(1995)
Nat Genet
, vol.10
, pp. 104-110
-
-
Trottier, Y.1
Devys, D.2
Imbert, G.3
Saudou, F.4
An, I.5
-
4
-
-
14644419638
-
Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation
-
Bowman AB, Yoo SY, Dantuma NP, Zoghbi HY (2005) Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation. Hum Mol Genet 14: 679-691.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 679-691
-
-
Bowman, A.B.1
Yoo, S.Y.2
Dantuma, N.P.3
Zoghbi, H.Y.4
-
5
-
-
2942708228
-
Mechanism of neurodegenerative disease: Role of the ubiquitin proteasome system
-
Petrucelli L, Dawson TM (2004) Mechanism of neurodegenerative disease: role of the ubiquitin proteasome system. Ann Med 36: 315-320.
-
(2004)
Ann Med
, vol.36
, pp. 315-320
-
-
Petrucelli, L.1
Dawson, T.M.2
-
6
-
-
4444274236
-
Accumulation of aberrant ubiquitin induces aggregate formation and cell death in polyglutamine diseases
-
de Pril R, Fischer DF, Maat-Schieman ML, Hobo B, de Vos RA, et al. (2004) Accumulation of aberrant ubiquitin induces aggregate formation and cell death in polyglutamine diseases. Hum Mol Genet 13: 1803-1813.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1803-1813
-
-
de Pril, R.1
Fischer, D.F.2
Maat-Schieman, M.L.3
Hobo, B.4
de Vos, R.A.5
-
7
-
-
0030016595
-
Structure and functions of the 20S and 26S proteasomes
-
Coux O, Tanaka K, Goldberg AL (1996) Structure and functions of the 20S and 26S proteasomes. Annu Rev Biochem 65: 801-847.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 801-847
-
-
Coux, O.1
Tanaka, K.2
Goldberg, A.L.3
-
8
-
-
27144512435
-
The ubiquitin-proteasome system and neurodegenerative disorders
-
Layfield R, Lowe J, Bedford L (2005) The ubiquitin-proteasome system and neurodegenerative disorders. Essays Biochem 41: 157-171.
-
(2005)
Essays Biochem
, vol.41
, pp. 157-171
-
-
Layfield, R.1
Lowe, J.2
Bedford, L.3
-
9
-
-
4444303263
-
Generalized brain and skin proteasome inhibition in Huntington's disease
-
Seo H, Sonntag KC, Isacson O (2004) Generalized brain and skin proteasome inhibition in Huntington's disease. Ann Neurol 56: 319-328.
-
(2004)
Ann Neurol
, vol.56
, pp. 319-328
-
-
Seo, H.1
Sonntag, K.C.2
Isacson, O.3
-
10
-
-
27644585391
-
Purification, crystallization, and X-ray analysis of the yeast 20S proteasome
-
Groll M, Huber R (2005) Purification, crystallization, and X-ray analysis of the yeast 20S proteasome. Methods Enzymol 398: 329-336.
-
(2005)
Methods Enzymol
, vol.398
, pp. 329-336
-
-
Groll, M.1
Huber, R.2
-
11
-
-
0033766480
-
A gated channel into the proteasome core particle
-
Groll M, Bajorek M, Kohler A, Moroder L, Rubin DM, et al. (2000) A gated channel into the proteasome core particle. Nat Struct Biol 7: 1062-1067.
-
(2000)
Nat Struct Biol
, vol.7
, pp. 1062-1067
-
-
Groll, M.1
Bajorek, M.2
Kohler, A.3
Moroder, L.4
Rubin, D.M.5
-
12
-
-
33646841837
-
Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate
-
Kisselev AF, Callard A, Goldberg AL (2006) Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate. J Biol Chem 281: 8582-8590.
-
(2006)
J Biol Chem
, vol.281
, pp. 8582-8590
-
-
Kisselev, A.F.1
Callard, A.2
Goldberg, A.L.3
-
13
-
-
0141704418
-
The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites
-
Kisselev AF, Garcia-Calvo M, Overkleeft HS, Peterson E, Pennington MW, et al. (2003) The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites. J Biol Chem 278: 35869-35877.
-
(2003)
J Biol Chem
, vol.278
, pp. 35869-35877
-
-
Kisselev, A.F.1
Garcia-Calvo, M.2
Overkleeft, H.S.3
Peterson, E.4
Pennington, M.W.5
-
14
-
-
0033965851
-
The proteasome activator 11 S REG (PA28) and class I antigen presentation
-
Rechsteiner M, Realini C, Ustrell V (2000) The proteasome activator 11 S REG (PA28) and class I antigen presentation. Biochem J 345 Pt 1: 1-15.
-
(2000)
Biochem J
, vol.345
, Issue.PART 1
, pp. 1-15
-
-
Rechsteiner, M.1
Realini, C.2
Ustrell, V.3
-
15
-
-
0033529596
-
The proteasome, a novel protease regulated by multiple mechanisms
-
DeMartino GN, Slaughter CA (1999) The proteasome, a novel protease regulated by multiple mechanisms. J Biol Chem 274: 22123-22126.
-
(1999)
J Biol Chem
, vol.274
, pp. 22123-22126
-
-
DeMartino, G.N.1
Slaughter, C.A.2
-
16
-
-
0037101839
-
Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses
-
Sipione S, Rigamonti D, Valenza M, Zuccato C, Conti L, et al. (2002) Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses. Hum Mol Genet 11: 1953-1965.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1953-1965
-
-
Sipione, S.1
Rigamonti, D.2
Valenza, M.3
Zuccato, C.4
Conti, L.5
-
17
-
-
0029619753
-
Inhibition of ubiquitin-mediated proteolysis by the Arabidopsis 26 S protease subunit S5a
-
Deveraux Q, van Nocker S, Mahaffey D, Vierstra R, Rechsteiner M (1995) Inhibition of ubiquitin-mediated proteolysis by the Arabidopsis 26 S protease subunit S5a. J Biol Chem 270: 29660-29663.
-
(1995)
J Biol Chem
, vol.270
, pp. 29660-29663
-
-
Deveraux, Q.1
van Nocker, S.2
Mahaffey, D.3
Vierstra, R.4
Rechsteiner, M.5
-
18
-
-
0028087582
-
PA700, an ATP-dependent activator of the 20 S proteasome, is an ATPase containing multiple members of a nucleotide-binding protein family
-
DeMartino GN, Moomaw CR, Zagnitko OP, Proske RJ, Chu-Ping M, et al. (1994) PA700, an ATP-dependent activator of the 20 S proteasome, is an ATPase containing multiple members of a nucleotide-binding protein family. J Biol Chem 269: 20878-20884.
-
(1994)
J Biol Chem
, vol.269
, pp. 20878-20884
-
-
DeMartino, G.N.1
Moomaw, C.R.2
Zagnitko, O.P.3
Proske, R.J.4
Chu-Ping, M.5
-
19
-
-
0025899234
-
Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture
-
Cory AH, Owen TC, Barltrop JA, Cory JG (1991) Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun 3: 207-212.
-
(1991)
Cancer Commun
, vol.3
, pp. 207-212
-
-
Cory, A.H.1
Owen, T.C.2
Barltrop, J.A.3
Cory, J.G.4
-
20
-
-
0034737299
-
Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease
-
Yamamoto A, Lucas JJ, Hen R (2000) Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease. Cell 101: 57-66.
-
(2000)
Cell
, vol.101
, pp. 57-66
-
-
Yamamoto, A.1
Lucas, J.J.2
Hen, R.3
-
21
-
-
0035889973
-
Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease
-
Martin-Aparicio E, Yamamoto A, Hernandez F, Hen R, Avila J, et al. (2001) Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease. J Neurosci 21: 8772-8781.
-
(2001)
J Neurosci
, vol.21
, pp. 8772-8781
-
-
Martin-Aparicio, E.1
Yamamoto, A.2
Hernandez, F.3
Hen, R.4
Avila, J.5
-
22
-
-
0037728958
-
Proteasome inhibitors induce intracellular protein aggregation and cell death by an oxygen-dependent mechanism
-
Demasi M, Davies KJ (2003) Proteasome inhibitors induce intracellular protein aggregation and cell death by an oxygen-dependent mechanism. FEBS Lett 542: 89-94.
-
(2003)
FEBS Lett
, vol.542
, pp. 89-94
-
-
Demasi, M.1
Davies, K.J.2
-
23
-
-
0033030565
-
Evidence for proteasome involvement in polyglutamine disease: Localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro
-
Chai Y, Koppenhafer SL, Shoesmith SJ, Perez MK, Paulson HL (1999) Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro. Hum Mol Genet 8: 673-682.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 673-682
-
-
Chai, Y.1
Koppenhafer, S.L.2
Shoesmith, S.J.3
Perez, M.K.4
Paulson, H.L.5
-
24
-
-
33644775636
-
Mutant huntingtin: Nuclear translocation and cytotoxicity mediated by GAPDH
-
Bae BI, Hara MR, Cascio MB, Wellington CL, Hayden MR, et al. (2006) Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH. Proc Natl Acad Sci U S A 103: 3405-3409.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 3405-3409
-
-
Bae, B.I.1
Hara, M.R.2
Cascio, M.B.3
Wellington, C.L.4
Hayden, M.R.5
-
25
-
-
2542436167
-
Modulating huntingtin half-life alters polyglutamine-dependent aggregate formation and cell toxicity
-
Kaytor MD, Wilkinson KD, Warren ST (2004) Modulating huntingtin half-life alters polyglutamine-dependent aggregate formation and cell toxicity. J Neurochem 89: 962-973.
-
(2004)
J Neurochem
, vol.89
, pp. 962-973
-
-
Kaytor, M.D.1
Wilkinson, K.D.2
Warren, S.T.3
-
26
-
-
4043057946
-
RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia
-
Xia H, Mao Q, Eliason SL, Harper SQ, Martins IH, et al. (2004) RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia. Nat Med 10: 816-820.
-
(2004)
Nat Med
, vol.10
, pp. 816-820
-
-
Xia, H.1
Mao, Q.2
Eliason, S.L.3
Harper, S.Q.4
Martins, I.H.5
-
27
-
-
33644540193
-
Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway
-
Yamamoto A, Cremona ML, Rothman JE (2006) Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway. J Cell Biol 172: 719-731.
-
(2006)
J Cell Biol
, vol.172
, pp. 719-731
-
-
Yamamoto, A.1
Cremona, M.L.2
Rothman, J.E.3
-
28
-
-
33644850056
-
Progressive disruption of cellular protein folding in models of polyglutamine diseases
-
Gidalevitz T, Ben-Zvi A, Ho KH, Brignull HR, Morimoto RI (2006) Progressive disruption of cellular protein folding in models of polyglutamine diseases. Science 311: 1471-1474.
-
(2006)
Science
, vol.311
, pp. 1471-1474
-
-
Gidalevitz, T.1
Ben-Zvi, A.2
Ho, K.H.3
Brignull, H.R.4
Morimoto, R.I.5
-
29
-
-
33746932115
-
-
J Neurochem
-
Diaz-Hernandez M, Valera AG, Moran MA, Gomez-Ramos P, Alvarez-Castelao B, et al. (2006) Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain. J Neurochem..
-
(2006)
Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain
-
-
Diaz-Hernandez, M.1
Valera, A.G.2
Moran, M.A.3
Gomez-Ramos, P.4
Alvarez-Castelao, B.5
-
30
-
-
0242499460
-
Will preventing protein aggregates live up to its promise as prophylaxis against neurodegenerative diseases?
-
Lee HG, Petersen RB, Zhu X, Honda K, Aliev G, et al. (2003) Will preventing protein aggregates live up to its promise as prophylaxis against neurodegenerative diseases? Brain Pathol 13: 630-638.
-
(2003)
Brain Pathol
, vol.13
, pp. 630-638
-
-
Lee, H.G.1
Petersen, R.B.2
Zhu, X.3
Honda, K.4
Aliev, G.5
-
31
-
-
0030919567
-
Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia
-
Browne SE, Bowling AC, MacGarvey U, Baik MJ, Berger SC, et al. (1997) Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia. Ann Neurol 41: 646-653.
-
(1997)
Ann Neurol
, vol.41
, pp. 646-653
-
-
Browne, S.E.1
Bowling, A.C.2
MacGarvey, U.3
Baik, M.J.4
Berger, S.C.5
-
32
-
-
1842533573
-
Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway
-
Ruan Q, Lesort M, MacDonald ME, Johnson GV (2004) Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway. Hum Mol Genet 13: 669-681.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 669-681
-
-
Ruan, Q.1
Lesort, M.2
MacDonald, M.E.3
Johnson, G.V.4
-
33
-
-
0022446150
-
Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid
-
Beal MF, Kowall NW, Ellison DW, Mazurek MF, Swartz KJ, et al. (1986) Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature 321: 168-171.
-
(1986)
Nature
, vol.321
, pp. 168-171
-
-
Beal, M.F.1
Kowall, N.W.2
Ellison, D.W.3
Mazurek, M.F.4
Swartz, K.J.5
-
34
-
-
0023788071
-
Systemic approaches to modifying quinolinic acid striatal lesions in rats
-
Beal MF, Kowall NW, Swartz KJ, Ferrante RJ, Martin JB (1988) Systemic approaches to modifying quinolinic acid striatal lesions in rats. J Neurosci 8: 3901-3908.
-
(1988)
J Neurosci
, vol.8
, pp. 3901-3908
-
-
Beal, M.F.1
Kowall, N.W.2
Swartz, K.J.3
Ferrante, R.J.4
Martin, J.B.5
-
35
-
-
0024401866
-
Short- and long-term survival of large neurons in the excitotoxic lesioned rat caudate nucleus: A light and electron microscopic study
-
Roberts RC, DiFiglia M (1989) Short- and long-term survival of large neurons in the excitotoxic lesioned rat caudate nucleus: a light and electron microscopic study. Synapse 3: 363-371.
-
(1989)
Synapse
, vol.3
, pp. 363-371
-
-
Roberts, R.C.1
DiFiglia, M.2
-
36
-
-
1542724417
-
Immune defects in 28-kDa proteasome activator gamma-deficient mice
-
Barton LF, Runnels HA, Schell TD, Cho Y, Gibbons R, et al. (2004) Immune defects in 28-kDa proteasome activator gamma-deficient mice. J Immunol 172: 3948-3954.
-
(2004)
J Immunol
, vol.172
, pp. 3948-3954
-
-
Barton, L.F.1
Runnels, H.A.2
Schell, T.D.3
Cho, Y.4
Gibbons, R.5
-
37
-
-
0027185178
-
Relationships between stress protein induction and NMDA-mediated neuronal death in the entorhinal cortex
-
Yee WM, Frim DM, Isacson O (1993) Relationships between stress protein induction and NMDA-mediated neuronal death in the entorhinal cortex. Exp Brain Res 94: 193-202.
-
(1993)
Exp Brain Res
, vol.94
, pp. 193-202
-
-
Yee, W.M.1
Frim, D.M.2
Isacson, O.3
-
38
-
-
33646585129
-
Quinolinic acid modulates the activity of src family kinases in rat striatum: In vivo and in vitro studies
-
Metere A, Mallozzi C, Minetti M, Domenici MR, Pezzola A, et al. (2006) Quinolinic acid modulates the activity of src family kinases in rat striatum: in vivo and in vitro studies. J Neurochem 97: 1327-1336.
-
(2006)
J Neurochem
, vol.97
, pp. 1327-1336
-
-
Metere, A.1
Mallozzi, C.2
Minetti, M.3
Domenici, M.R.4
Pezzola, A.5
-
39
-
-
0027289605
-
Mitochondrial impairment reduces the threshold for in vivo NMDA-mediated neuronal death in the striatum
-
Simpson JR, Isacson O (1993) Mitochondrial impairment reduces the threshold for in vivo NMDA-mediated neuronal death in the striatum. Exp Neurol 121: 57-64.
-
(1993)
Exp Neurol
, vol.121
, pp. 57-64
-
-
Simpson, J.R.1
Isacson, O.2
-
40
-
-
29144468251
-
3-Nitropropionic acid: A mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease
-
Brouillet E, Jacquard C, Bizat N, Blum D (2005) 3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease. J Neurochem 95: 1521-1540.
-
(2005)
J Neurochem
, vol.95
, pp. 1521-1540
-
-
Brouillet, E.1
Jacquard, C.2
Bizat, N.3
Blum, D.4
-
41
-
-
33845614355
-
Brain mitochondrial defects amplify intracellular [Ca2+] rise and neurodegeneration but not Ca2+ entry during NMDA receptor activation
-
Jacquard C, Trioulier Y, Cosker F, Escartin C, Bizat N, et al. (2006) Brain mitochondrial defects amplify intracellular [Ca2+] rise and neurodegeneration but not Ca2+ entry during NMDA receptor activation. Faseb J 20: 1021-1023.
-
(2006)
Faseb J
, vol.20
, pp. 1021-1023
-
-
Jacquard, C.1
Trioulier, Y.2
Cosker, F.3
Escartin, C.4
Bizat, N.5
-
42
-
-
17044444591
-
Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1
-
Kominami K, Okura N, Kawamura M, DeMartino GN, Slaughter CA, et al. (1997) Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1. Mol Biol Cell 8: 171-187.
-
(1997)
Mol Biol Cell
, vol.8
, pp. 171-187
-
-
Kominami, K.1
Okura, N.2
Kawamura, M.3
DeMartino, G.N.4
Slaughter, C.A.5
-
43
-
-
0035075334
-
Molecular dissection of the 11S REG (PA28) proteasome activators
-
Li J, Rechsteiner M (2001) Molecular dissection of the 11S REG (PA28) proteasome activators. Biochimie 83: 373-383.
-
(2001)
Biochimie
, vol.83
, pp. 373-383
-
-
Li, J.1
Rechsteiner, M.2
-
44
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
Glickman MH, Ciechanover A (2002) The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82: 373-428.
-
(2002)
Physiol Rev
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
45
-
-
29644433718
-
Proteasome impairment does not contribute to pathogenesis in R6/2 Huntington's disease mice: Exclusion of proteasome activator REGgamma as a therapeutic target
-
Bett JS, Goellner GM, Woodman B, Pratt G, Rechsteiner M, et al. (2006) Proteasome impairment does not contribute to pathogenesis in R6/2 Huntington's disease mice: exclusion of proteasome activator REGgamma as a therapeutic target. Hum Mol Genet 15: 33-44.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 33-44
-
-
Bett, J.S.1
Goellner, G.M.2
Woodman, B.3
Pratt, G.4
Rechsteiner, M.5
-
46
-
-
55349085552
-
Generalized ubiquitin proteasome inhibitiion in Huntington's disease patients' brains is modeled in some but not all HD transgenic mice
-
Seo H, Sonntag KC, Lee CH, Kim HT, Isacson O (2005) Generalized ubiquitin proteasome inhibitiion in Huntington's disease patients' brains is modeled in some but not all HD transgenic mice. Annual conference of Society for Neuroscience.
-
(2005)
Annual conference of Society for Neuroscience
-
-
Seo, H.1
Sonntag, K.C.2
Lee, C.H.3
Kim, H.T.4
Isacson, O.5
-
47
-
-
0033587760
-
Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity
-
Hansson O, Petersen A, Leist M, Nicotera P, Castilho RF, et al. (1999) Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity. Proc Natl Acad Sci U S A 96: 8727-8732.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 8727-8732
-
-
Hansson, O.1
Petersen, A.2
Leist, M.3
Nicotera, P.4
Castilho, R.F.5
-
48
-
-
0031743608
-
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
-
Zufferey R, Dull T, Mandel RJ, Bukovsky A, Quiroz D, et al. (1998) Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J Virol 72: 9873-9880.
-
(1998)
J Virol
, vol.72
, pp. 9873-9880
-
-
Zufferey, R.1
Dull, T.2
Mandel, R.J.3
Bukovsky, A.4
Quiroz, D.5
-
49
-
-
0034657112
-
Wild-type huntingtin protects from apoptosis upstream of caspase-3
-
Rigamonti D, Bauer JH, De-Fraja C, Conti L, Sipione S, et al. (2000) Wild-type huntingtin protects from apoptosis upstream of caspase-3. J Neurosci 20: 3705-3713.
-
(2000)
J Neurosci
, vol.20
, pp. 3705-3713
-
-
Rigamonti, D.1
Bauer, J.H.2
De-Fraja, C.3
Conti, L.4
Sipione, S.5
-
50
-
-
0030926777
-
Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation
-
Craiu A, Gaczynska M, Akopian T, Gramm CF, Fenteany G, et al. (1997) Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation. J Biol Chem 272: 13437-13445.
-
(1997)
J Biol Chem
, vol.272
, pp. 13437-13445
-
-
Craiu, A.1
Gaczynska, M.2
Akopian, T.3
Gramm, C.F.4
Fenteany, G.5
|