Recovery of liver mass without proliferation of hepatocytes after partial hepatectomy in Skp2-deficient mice

Cancer Research

Volumn 62, Issue 4, 2002, Pages 995-999

  Minamishima, Yohji A ^a   Nakayama, Keiko ^a   Nakayama, Kei Ichi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P27;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LIVER REGENERATION; MOUSE; NONHUMAN; PARTIAL HEPATECTOMY; POLYPLOIDY; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; CELL CYCLE PROTEINS; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; FEMALE; HEPATECTOMY; HEPATOCYTES; LIVER REGENERATION; MICE; MITOSIS; ORGAN SIZE; PLOIDIES; S-PHASE KINASE-ASSOCIATED PROTEINS; TUMOR SUPPRESSOR PROTEINS;

EID: 0036172085     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Coordination of cell growth with cell division
2. Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
3. Kip1, polyploidy and centrosome overduplication
4. Kip1 protein: Prognostic implications in primary breast cancer
5. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
6. Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
7. High expression of S-phase kinase-interacting protein 2, human F-box protein, correlates with poor prognosis in oral squamous cell carcinomas
8. Kip1 is haplo-insufficient for tumour suppression
9. Liver regeneration
10. 1 transition mediated by a Skp2-independent ubiquitination pathway
11. Skp2 are essential elements of the cyclin A-CDK2 S phase kinase
12. p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase
13. Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18
14. Liver gene disruptions: Winners by KO?
15. Skp2 is oncogenic and overexpressed in human cancers
16. Role of the F-box protein Skp2 in lymphomagenesis
17. Kip1 and of its ubiquitin ligase subunit Skp2 in colorectal carcinomas
18. Induction of hepatocyte proliferation and liver hyperplasia by the targeted expression of cyclin E and skp2
19. Hepatic polyploidy and liver growth control
20. Partial hepatectomy-induced polyploidy attenuates hepatocyte replication and activates cell aging events