A standardized root extract of Withania somnifera and its major constituent withanolide-A elicit humoral and cell-mediated immune responses by up regulation of Th1-dominant polarization in BALB/c mice

Life Sciences

Volumn 80, Issue 16, 2007, Pages 1525-1538

  Malik, Fayaz ^a   Singh, Jaswant ^a   Khajuria, Anamika ^a   Suri, Krishan A ^a   Satti, Naresh K ^a   Singh, Surjeet ^a   Kaul, Maharaj K ^a   Kumar, Arun ^a   Bhatia, Aruna ^b   Qazi, Ghulam N ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^b PUNJABI UNIVERSITY   (India)

Author keywords

Cytokines; Immunoglobulins; Lymphocyte surface markers; Withania somnifera; Withanolide A

Indexed keywords

CD19 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; DEXAMETHASONE; GAMMA INTERFERON; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN M; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 4; LEVAMISOLE; LYMPHOCYTE SURFACE MARKER; NITRITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WITHANIA SOMNIFERA EXTRACT; WITHANOLIDE; WITHANOLIDE A;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL POLARITY; CELL PROLIFERATION; CELL STIMULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HELPER CELL; HUMORAL IMMUNITY; IMMUNIZATION; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; POLARIZATION; SPLEEN CELL; T LYMPHOCYTE; TH1 CELL; TH2 CELL; UPREGULATION; WITHANIA SOMNIFERA;

ANIMALS; ANTIBODY FORMATION; FLOW CYTOMETRY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERFERON TYPE II; INTERLEUKIN-2; INTERLEUKIN-4; MACROPHAGES; MICE; MICE, INBRED BALB C; PLANT EXTRACTS; PLANT ROOTS; TH1 CELLS; UP-REGULATION; WITHANIA;

MUS; WITHANIA SOMNIFERA;

EID: 33947148594     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.01.029     Document Type: Article

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