Essential role of p53 in trophoblastic apoptosis induced in the developing rodent placenta by treatment with a DNA-damaging agent

Apoptosis

Volumn 12, Issue 10, 2007, Pages 1743-1754

  Yamauchi, Hirofumi ^a   Katayama, Kei Ichi ^a   Ueno, Masaki ^a   He, Xi Jun ^a   Mikami, Takashi ^a   Uetsuka, Koji ^a   Doi, Kunio ^a   Nakayama, Hiroyuki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Apoptosis; DNA damage; p53; Placenta; Trophoblast

Indexed keywords

CASPASE 9; CHECKPOINT KINASE 1; CYTARABINE; CYTOCHROME C; DNA; HISTONE H2AX; MESSENGER RNA; PROTEIN P53; TRANSCRIPTION FACTOR; TRYPSIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL STRESS; CONTROLLED STUDY; DNA DAMAGE; DRUG MECHANISM; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; GENE FUNCTION; MOUSE; NONHUMAN; PHYSIOLOGY; PLACENTA; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RODENT; TROPHOBLAST; UPREGULATION; WILD TYPE;

ANIMALS; ANTIGENS, CD95; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; CASPASE 9; CYTARABINE; CYTOCHROMES C; DNA DAMAGE; ENZYME ACTIVATION; FEMALE; IN SITU NICK-END LABELING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; PLACENTA; PREGNANCY; RANDOM ALLOCATION; RATS; RATS, WISTAR; TROPHOBLASTS; TUMOR SUPPRESSOR PROTEIN P53;

ARA; MUS; RATTUS; RODENTIA;

EID: 34848877478     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-007-0099-z     Document Type: Article

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