2001 Warkany lecture: To die or not to die, the role of apoptosis in normal and abnormal mammalian development

Teratology

Volumn 65, Issue 5, 2002, Pages 228-239

  Mirkes, Philip E ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 9; CYTOCHROME C; DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2;

APOPTOSIS; BIRTH DEFECT; CAENORHABDITIS ELEGANS; CELL DEATH; CONFERENCE PAPER; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; MAMMAL; MITOCHONDRION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; TERATOGENESIS;

ANIMALS; APOPTOSIS; CAENORHABDITIS ELEGANS; CASPASES; EMBRYONIC AND FETAL DEVELOPMENT; HUMANS; MAMMALS; MICE; NECROSIS; TERATOGENS;

CAENORHABDITIS ELEGANS; INTRACISTERNAL A-PARTICLES; MAMMALIA; NEMATODA;

EID: 0036245045     PISSN: 00403709     EISSN: None     Source Type: Journal    
DOI: 10.1002/tera.10049     Document Type: Conference Paper

References (50)

1. Apaf-1 (CED4 homolog) regulates PCD in mammalian development
2. Proteases for cell suicide: Functions and regulation of caspases
3. Targeted disruption of caspases in mice: What they tell us about the functions of individual caspases in apoptosis
4. X-linked IAP is a direct inhibitor of cell death proteases
5. IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
6. IAP family proteins-suppressors of apoptosis
7. Molecular genetics of cell death in the nematode Caenorhabditis elegans
8. Selective vulnerability of embryonic cell populations to ethanol-induced apoptosis: Implications for alcohol-related birth defects and neurodevelopmental disorder
9. Genetic control of PCD in the nematode Caenorhabditis elegans
10. Activation of apoptosis in early mouse embryos by 2′-deoxyadenosine exposure
11. Cell deaths in normal vertebrate ontogeny
12. Differential requirement for caspase 9 in apoptotic pathways in vivo
13. Characterization of XIAP-deficient mice
14. The biochemistry of apoptosis
15. C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
16. Apaf-1 deficiency and neural tube closure defects are found in fog mice
17. Livin, a novel inhibitor of apoptosis protein family member
18. Apoptosis: A basic phenomenon with wide-ranging implications in tissue kinetics
19. The postembryonic cell lineages of the hermaphrodite and male gonads in Caenorhabditis elegans
20. Cell death
21. Caspase-3-generated fragment of gelsolin: Effector of morphological change in apoptosis
22. Decreased apoptosis in the brain and premature lethality in CPP-32 deficient mice
23. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
24. Teratogen-induced activation of caspace-6 and caspase-7 in day 9 mouse embryos
25. Caspase-3-induced augmentation of the intrinsic, mitochondrial apoptotic pathway
26. The molecular mechanism of PCD in C. elegans
27. Cell death in teratogenesis
28. Genetics of PCD in C. elegans: Past, present and future
29. Hereditary and induced modifications of the normal necrotic patterns in the developing limb buds of the rat and mouse; facts and hypotheses
30. Teratogen-induced cell death in postimplantation mouse embryos: Differential tissue sensitivity and hallmarks of apoptosis
31. Cytochrome c release from mitochondria of early postimplantation murine embryos exposed to 4-hydroperoxycyclophosphamide, heat shock, and staurosporine
32. Cell death during development of the nervous system
33. Characterization of DNA fragmentation events caused by genotoxic and non-genotoxic agents
34. Lamin proteolysis facilitates nuclear events during apoptosis
35. Bcl-2 family proteins
36. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
37. Cell death and reduced proliferative rate
38. Apoptosis signaling
39. Teratogens and craniofacial malformations: Relationships to cell death
40. Post-embryonic cell lineage of the nematode Caenorhabditis elegans
41. The embryonic cell lineage of the nematode Caenorhabditis elegans
42. PCD and N-acetoxy-2-acetylaminofluorene-induced apoptosis in the rat embryo
43. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
44. Protease involvement in fodrin cleavage and phosphatidylserine exposure in apoptosis
45. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
46. Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
47. Apaf-1 is required for mitochondrial pathways of apoptosis and brain development
48. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin b-converting enzyme
49. Caspase knockouts: Matters of life and death