메뉴 건너뛰기




Volumn 13, Issue 37, 2007, Pages 4955-4959

Effects of ethanol on hepatic cellular replication and cell cycle progression

Author keywords

Acetaldehyde; Alcoholic liver disease; Cell cycle; Cyclin dependent kinases; Ethanol metabolism; Liver regeneration

Indexed keywords

ACETALDEHYDE; ALCOHOL; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P21; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; STAT3 PROTEIN; UNCOUPLING PROTEIN 2;

EID: 34848860809     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v13.i37.4955     Document Type: Review
Times cited : (21)

References (45)
  • 1
    • 0024244685 scopus 로고
    • Biochemical and molecular basis of alcohol-induced injury to liver and other tissues
    • Lieber CS. Biochemical and molecular basis of alcohol-induced injury to liver and other tissues. N Engl J Med 1988; 319: 1639-1650
    • (1988) N Engl J Med , vol.319 , pp. 1639-1650
    • Lieber, C.S.1
  • 2
    • 0030935567 scopus 로고    scopus 로고
    • Cytochrome P-4502E1: Its physiological and pathological role
    • Lieber CS. Cytochrome P-4502E1: its physiological and pathological role. Physiol Rev 1997; 77: 517-544
    • (1997) Physiol Rev , vol.77 , pp. 517-544
    • Lieber, C.S.1
  • 3
    • 0018398044 scopus 로고
    • Inhibition of hepatic regeneration in rats by acute and chronic ethanol intoxication
    • Wands JR, Carter EA, Bucher NL, Isselbacher KJ. Inhibition of hepatic regeneration in rats by acute and chronic ethanol intoxication. Gastroenterology 1979; 77: 528-531
    • (1979) Gastroenterology , vol.77 , pp. 528-531
    • Wands, J.R.1    Carter, E.A.2    Bucher, N.L.3    Isselbacher, K.J.4
  • 4
    • 0020048371 scopus 로고
    • Inhibition of liver regeneration by chronic alcohol administration
    • Duguay L, Coutu D, Hetu C, Joly JG. Inhibition of liver regeneration by chronic alcohol administration. Gut 1982; 23: 8-13
    • (1982) Gut , vol.23 , pp. 8-13
    • Duguay, L.1    Coutu, D.2    Hetu, C.3    Joly, J.G.4
  • 5
    • 0022521779 scopus 로고
    • Incubation of rat hepatic tumor cells with ethanol and acetaldehyde in vitro: Effects on growth rate, albumin secretion and cellular protein content
    • Higgins PJ, Borenfreund E. Incubation of rat hepatic tumor cells with ethanol and acetaldehyde in vitro: effects on growth rate, albumin secretion and cellular protein content. Digestion 1986; 34: 161-168
    • (1986) Digestion , vol.34 , pp. 161-168
    • Higgins, P.J.1    Borenfreund, E.2
  • 6
    • 0023022069 scopus 로고
    • Alterations in growth rate and cell cycle kinetics of rat liver tumor cells cultured in ethanol-containing medium. In vitro model of proliferative restriction in response to ethanol exposure
    • Higgins PJ, Borenfreund E. Alterations in growth rate and cell cycle kinetics of rat liver tumor cells cultured in ethanol-containing medium. In vitro model of proliferative restriction in response to ethanol exposure. Biochem Pharmacol 1986; 35: 3857-3862
    • (1986) Biochem Pharmacol , vol.35 , pp. 3857-3862
    • Higgins, P.J.1    Borenfreund, E.2
  • 8
    • 0023809014 scopus 로고
    • Ethanol-induced inhibition of liver cell function: I. Effect of ethanol on hormone stimulated hepatocyte DNA synthesis and the role of ethanol metabolism
    • Carter EA, Wands JR. Ethanol-induced inhibition of liver cell function: I. Effect of ethanol on hormone stimulated hepatocyte DNA synthesis and the role of ethanol metabolism. Alcohol Clin Exp Res 1988; 12: 555-562
    • (1988) Alcohol Clin Exp Res , vol.12 , pp. 555-562
    • Carter, E.A.1    Wands, J.R.2
  • 9
    • 0036017180 scopus 로고    scopus 로고
    • Ethanol, oxidative stress, and cytokine-induced liver cell injury
    • Hoek JB, Pastorino JG. Ethanol, oxidative stress, and cytokine-induced liver cell injury. Alcohol 2002; 27: 63-68
    • (2002) Alcohol , vol.27 , pp. 63-68
    • Hoek, J.B.1    Pastorino, J.G.2
  • 10
    • 0035834739 scopus 로고    scopus 로고
    • Role of the FYVE finger and the RUN domain for the subcellular localization of Rabip4
    • Mari M, Macia E, Le Marchand-Brustel Y, Cormont M. Role of the FYVE finger and the RUN domain for the subcellular localization of Rabip4. J Biol Chem 2001; 276: 42501-42508
    • (2001) J Biol Chem , vol.276 , pp. 42501-42508
    • Mari, M.1    Macia, E.2    Le Marchand-Brustel, Y.3    Cormont, M.4
  • 12
    • 0036862006 scopus 로고    scopus 로고
    • Ethanol induces redox-sensitive cell-cycle inhibitors and inhibits liver regeneration after partial hepatectomy
    • Koteish A, Yang S, Lin H, Huang J, Diehl AM. Ethanol induces redox-sensitive cell-cycle inhibitors and inhibits liver regeneration after partial hepatectomy. Alcohol Clin Exp Res 2002; 26: 1710-1718
    • (2002) Alcohol Clin Exp Res , vol.26 , pp. 1710-1718
    • Koteish, A.1    Yang, S.2    Lin, H.3    Huang, J.4    Diehl, A.M.5
  • 13
    • 0034658541 scopus 로고    scopus 로고
    • Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
    • Hirano T, Ishihara K, Hibi M. Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors. Oncogene 2000; 19: 2548-2556
    • (2000) Oncogene , vol.19 , pp. 2548-2556
    • Hirano, T.1    Ishihara, K.2    Hibi, M.3
  • 14
    • 0031799747 scopus 로고    scopus 로고
    • Hepatic steatosis: Innocent bystander or guilty party?
    • Day CP, James OF. Hepatic steatosis: innocent bystander or guilty party? Hepatology 1998; 27: 1463-1466
    • (1998) Hepatology , vol.27 , pp. 1463-1466
    • Day, C.P.1    James, O.F.2
  • 15
    • 0035013288 scopus 로고    scopus 로고
    • Current concepts in the pathogenesis of alcoholic liver injury
    • Tsukamoto H, Lu SC. Current concepts in the pathogenesis of alcoholic liver injury. FASEB J 2001; 15: 1335-1349
    • (2001) FASEB J , vol.15 , pp. 1335-1349
    • Tsukamoto, H.1    Lu, S.C.2
  • 16
    • 0036314662 scopus 로고    scopus 로고
    • STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers
    • Torbenson M, Yang SQ, Liu HZ, Huang J, Gage W, Diehl AM. STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers. Am J Pathol 2002; 161: 155-156
    • (2002) Am J Pathol , vol.161 , pp. 155-156
    • Torbenson, M.1    Yang, S.Q.2    Liu, H.Z.3    Huang, J.4    Gage, W.5    Diehl, A.M.6
  • 17
    • 0033969421 scopus 로고    scopus 로고
    • Uncoupling proteins 2 and 3: Potential regulators of mitochondrial energy metabolism
    • Boss O, Hagen T, Lowell BB. Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism. Diabetes 2000; 49: 143-156
    • (2000) Diabetes , vol.49 , pp. 143-156
    • Boss, O.1    Hagen, T.2    Lowell, B.B.3
  • 18
    • 1242336976 scopus 로고    scopus 로고
    • Uncoupling protein-2 deficiency promotes oxidant stress and delays liver regeneration in mice
    • Horimoto M, Fulop P, Derdak Z, Wands JR, Baffy G. Uncoupling protein-2 deficiency promotes oxidant stress and delays liver regeneration in mice. Hepatology 2004; 39: 386-392
    • (2004) Hepatology , vol.39 , pp. 386-392
    • Horimoto, M.1    Fulop, P.2    Derdak, Z.3    Wands, J.R.4    Baffy, G.5
  • 21
    • 0036242560 scopus 로고    scopus 로고
    • Relationship between acetaldehyde levels and cell survival in ethanol-metabolizing hepatoma cells
    • Clemens DL, Forman A, Jerrells TR, Sorrell MF, Tuma DJ. Relationship between acetaldehyde levels and cell survival in ethanol-metabolizing hepatoma cells. Hepatology 2002; 35: 1196-1204
    • (2002) Hepatology , vol.35 , pp. 1196-1204
    • Clemens, D.L.1    Forman, A.2    Jerrells, T.R.3    Sorrell, M.F.4    Tuma, D.J.5
  • 22
    • 0042265643 scopus 로고    scopus 로고
    • Ethanol metabolism results in a G2/M cell-cycle arrest in recombinant Hep G2 cells
    • Clemens DL, Calisto LE, Sorrell MF, Tuma DJ. Ethanol metabolism results in a G2/M cell-cycle arrest in recombinant Hep G2 cells. Hepatology 2003; 38: 385-393
    • (2003) Hepatology , vol.38 , pp. 385-393
    • Clemens, D.L.1    Calisto, L.E.2    Sorrell, M.F.3    Tuma, D.J.4
  • 23
    • 0025246110 scopus 로고
    • Universal control mechanism regulating onset of M-phase
    • Nurse P. Universal control mechanism regulating onset of M-phase. Nature 1990; 344: 503-508
    • (1990) Nature , vol.344 , pp. 503-508
    • Nurse, P.1
  • 24
    • 0031470835 scopus 로고    scopus 로고
    • Checkpoint pathways come of age
    • Nurse P. Checkpoint pathways come of age. Cell 1997; 91: 865-867
    • (1997) Cell , vol.91 , pp. 865-867
    • Nurse, P.1
  • 25
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • Abraham RT. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 2001; 15: 2177-2196
    • (2001) Genes Dev , vol.15 , pp. 2177-2196
    • Abraham, R.T.1
  • 28
    • 0038418869 scopus 로고    scopus 로고
    • Chk1 and Chk2 kinases in checkpoint control and cancer
    • Bartek J, Lukas J. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 2003; 3: 421-429
    • (2003) Cancer Cell , vol.3 , pp. 421-429
    • Bartek, J.1    Lukas, J.2
  • 29
    • 0030867582 scopus 로고    scopus 로고
    • Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
    • Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ. Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 1997; 277: 1497-1501
    • (1997) Science , vol.277 , pp. 1497-1501
    • Sanchez, Y.1    Wong, C.2    Thoma, R.S.3    Richman, R.4    Wu, Z.5    Piwnica-Worms, H.6    Elledge, S.J.7
  • 31
    • 0034142034 scopus 로고    scopus 로고
    • The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
    • Shieh SY, Ahn J, Tamai K, Taya Y, Prives C. The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev 2000; 14: 289-300
    • (2000) Genes Dev , vol.14 , pp. 289-300
    • Shieh, S.Y.1    Ahn, J.2    Tamai, K.3    Taya, Y.4    Prives, C.5
  • 32
    • 0030611095 scopus 로고    scopus 로고
    • Mitotic and G2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216
    • Peng CY, Graves PR, Thoma RS, Wu Z, Shaw AS, Piwnica-Worms H. Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 1997; 277: 1501-1505
    • (1997) Science , vol.277 , pp. 1501-1505
    • Peng, C.Y.1    Graves, P.R.2    Thoma, R.S.3    Wu, Z.4    Shaw, A.S.5    Piwnica-Worms, H.6
  • 33
    • 0033579412 scopus 로고    scopus 로고
    • Regulation of the p53 tumor suppressor protein
    • Oren M. Regulation of the p53 tumor suppressor protein. J Biol Chem 1999; 274: 36031-36034
    • (1999) J Biol Chem , vol.274 , pp. 36031-36034
    • Oren, M.1
  • 34
    • 0030667702 scopus 로고    scopus 로고
    • DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
    • Shieh SY, Ikeda M, Taya Y, Prives C. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 1997; 91: 325-334
    • (1997) Cell , vol.91 , pp. 325-334
    • Shieh, S.Y.1    Ikeda, M.2    Taya, Y.3    Prives, C.4
  • 35
    • 0037184969 scopus 로고    scopus 로고
    • Acetylation of p53 inhibits its ubiquitination by Mdm2
    • Li M, Luo J, Brooks CL, Gu W. Acetylation of p53 inhibits its ubiquitination by Mdm2. J Biol Chem 2002; 277: 50607-50611
    • (2002) J Biol Chem , vol.277 , pp. 50607-50611
    • Li, M.1    Luo, J.2    Brooks, C.L.3    Gu, W.4
  • 36
    • 33646757232 scopus 로고    scopus 로고
    • The complexity of p53 stabilization and activation
    • Lavin MF, Gueven N. The complexity of p53 stabilization and activation. Cell Death Differ 2006; 13: 941-950
    • (2006) Cell Death Differ , vol.13 , pp. 941-950
    • Lavin, M.F.1    Gueven, N.2
  • 37
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997; 88: 323-331
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 38
    • 0035810054 scopus 로고    scopus 로고
    • Regulation of the G2/M transition by p53
    • Taylor WR, Stark GR. Regulation of the G2/M transition by p53. Oncogene 2001; 20: 1803-1815
    • (2001) Oncogene , vol.20 , pp. 1803-1815
    • Taylor, W.R.1    Stark, G.R.2
  • 39
    • 0035120616 scopus 로고    scopus 로고
    • Heterogeneity and plasticity of hepatocyte lineage cells
    • Sell S. Heterogeneity and plasticity of hepatocyte lineage cells. Hepatology 2001; 33: 738-750
    • (2001) Hepatology , vol.33 , pp. 738-750
    • Sell, S.1
  • 40
    • 0031913873 scopus 로고    scopus 로고
    • Inhibition of in vivo rat liver regeneration by 2-acetylaminofluorene affects the regulation of cell cycle-related proteins
    • Ohlson LC, Koroxenidou L, Hallstrom IP. Inhibition of in vivo rat liver regeneration by 2-acetylaminofluorene affects the regulation of cell cycle-related proteins. Hepatology 1998; 27: 691-696
    • (1998) Hepatology , vol.27 , pp. 691-696
    • Ohlson, L.C.1    Koroxenidou, L.2    Hallstrom, I.P.3
  • 41
    • 0033985856 scopus 로고    scopus 로고
    • Failure of regeneration of the steatotic rat liver: Disruption at two different levels in the regeneration pathway
    • Selzner M, Clavien PA. Failure of regeneration of the steatotic rat liver: disruption at two different levels in the regeneration pathway. Hepatology 2000; 31: 35-42
    • (2000) Hepatology , vol.31 , pp. 35-42
    • Selzner, M.1    Clavien, P.A.2
  • 43
    • 1242291937 scopus 로고    scopus 로고
    • Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease
    • Yang S, Koteish A, Lin H, Huang J, Roskams T, Dawson V, Diehl AM. Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease. Hepatology 2004; 39: 403-411
    • (2004) Hepatology , vol.39 , pp. 403-411
    • Yang, S.1    Koteish, A.2    Lin, H.3    Huang, J.4    Roskams, T.5    Dawson, V.6    Diehl, A.M.7
  • 44
    • 16244416190 scopus 로고    scopus 로고
    • Fibrosis correlates with a ductular reaction in hepatitis C: Roles of impaired replication, progenitor cells and steatosis
    • Clouston AD, Powell EE, Walsh MJ, Richardson MM, Demetris AJ, Jonsson JR. Fibrosis correlates with a ductular reaction in hepatitis C: roles of impaired replication, progenitor cells and steatosis. Hepatology 2005; 41: 809-818
    • (2005) Hepatology , vol.41 , pp. 809-818
    • Clouston, A.D.1    Powell, E.E.2    Walsh, M.J.3    Richardson, M.M.4    Demetris, A.J.5    Jonsson, J.R.6
  • 45
    • 0027413031 scopus 로고
    • Bile duct changes in alcoholic liver disease. The Veterans Administration Cooperative Study Group
    • Ray MB, Mendenhall CL, French SW, Gartside PS. Bile duct changes in alcoholic liver disease. The Veterans Administration Cooperative Study Group. Liver 1993; 13: 36-45
    • (1993) Liver , vol.13 , pp. 36-45
    • Ray, M.B.1    Mendenhall, C.L.2    French, S.W.3    Gartside, P.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.