-
2
-
-
0036637294
-
Liver regeneration
-
Diehl AM. Liver regeneration. Front Biosci 2002;7:e301-e314.
-
(2002)
Front Biosci
, vol.7
-
-
Diehl, A.M.1
-
3
-
-
0034007745
-
Liver regeneration
-
Fausto N. Liver regeneration. J Hepatol 2000;32:19-31.
-
(2000)
J Hepatol
, vol.32
, pp. 19-31
-
-
Fausto, N.1
-
5
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000;408:239-247.
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
6
-
-
0037133928
-
H2O2 induces a transient multi-phase cell cycle arrest in mouse fibroblasts through modulating cyclin D and p21Cip1 expression
-
Barnouin K, Dubuisson ML, Child ES, Fernandez de Mattos S, Glassford J, Medema RH, Mann DJ, et al. H2O2 induces a transient multi-phase cell cycle arrest in mouse fibroblasts through modulating cyclin D and p21Cip1 expression. J Biol Chem 2002;277:13761-13770.
-
(2002)
J Biol Chem
, vol.277
, pp. 13761-13770
-
-
Barnouin, K.1
Dubuisson, M.L.2
Child, E.S.3
Fernandez De Mattos, S.4
Glassford, J.5
Medema, R.H.6
Mann, D.J.7
-
7
-
-
0029803923
-
Independent regulation of JNK/p38 mitogen-activated protein kinases by metabolic oxidative stress in the liver
-
Mendelson KG, Contois LR, Tevosian SG, Davis RJ, Paulson KE. Independent regulation of JNK/p38 mitogen-activated protein kinases by metabolic oxidative stress in the liver. Proc Natl Acad Sci U S A 1996;93:12908-12913.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 12908-12913
-
-
Mendelson, K.G.1
Contois, L.R.2
Tevosian, S.G.3
Davis, R.J.4
Paulson, K.E.5
-
8
-
-
0015882341
-
The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen
-
Boveris A, Chance B. The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 1973;134:707-716.
-
(1973)
Biochem J
, vol.134
, pp. 707-716
-
-
Boveris, A.1
Chance, B.2
-
9
-
-
0036139856
-
The mitochondrial production of reactive oxygen species: Mechanisms and implications in human pathology
-
Lenaz G. The mitochondrial production of reactive oxygen species: mechanisms and implications in human pathology. IUBMB Life 2001;52:159-164.
-
(2001)
IUBMB Life
, vol.52
, pp. 159-164
-
-
Lenaz, G.1
-
10
-
-
0030809576
-
Reactive oxygen species, mitochondria, apoptosis and aging
-
Papa S, Skulachev VP. Reactive oxygen species, mitochondria, apoptosis and aging. Mol Cell Biochem 1997;174:305-319.
-
(1997)
Mol Cell Biochem
, vol.174
, pp. 305-319
-
-
Papa, S.1
Skulachev, V.P.2
-
11
-
-
0036554502
-
Mitochondrial superoxide radical formation is controlled by electron bifurcation to the high and low potential pathways
-
Staniek K, Gille L, Kozlov AV, Nohl H. Mitochondrial superoxide radical formation is controlled by electron bifurcation to the high and low potential pathways. Free Radic Res 2002;36:381-387.
-
(2002)
Free Radic Res
, vol.36
, pp. 381-387
-
-
Staniek, K.1
Gille, L.2
Kozlov, A.V.3
Nohl, H.4
-
12
-
-
0034659814
-
Mitochondrial adaptations to obesity-related oxidant stress
-
Yang S, Zhu H, Li Y, Lin H, Gabrielson K, Trush MA, Diehl AM. Mitochondrial adaptations to obesity-related oxidant stress. Arch Biochem Biophys 2000;378:259-268.
-
(2000)
Arch Biochem Biophys
, vol.378
, pp. 259-268
-
-
Yang, S.1
Zhu, H.2
Li, Y.3
Lin, H.4
Gabrielson, K.5
Trush, M.A.6
Diehl, A.M.7
-
13
-
-
0034951169
-
Mitochondria, oxygen free radicals, and apoptosis
-
Raha S, Robinson BH. Mitochondria, oxygen free radicals, and apoptosis. Am J Med Genet 2001;106:62-70.
-
(2001)
Am J Med Genet
, vol.106
, pp. 62-70
-
-
Raha, S.1
Robinson, B.H.2
-
14
-
-
0031019249
-
Uncoupling protein-2: A novel gene linked to obesity and hyperinsulinemia
-
Fleury C, Neverova M, Collins S, Raimbault S, Champigny O, Levi-Meyrueis C, Bouillaud F, et al. Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nat Genet 1997;15:269-272.
-
(1997)
Nat Genet
, vol.15
, pp. 269-272
-
-
Fleury, C.1
Neverova, M.2
Collins, S.3
Raimbault, S.4
Champigny, O.5
Levi-Meyrueis, C.6
Bouillaud, F.7
-
15
-
-
15144356206
-
Cloning and characterization of an uncoupling protein homolog: A potential molecular mediator of human thermogenesis
-
Gimeno RE, Dembski M, Weng X, Deng N, Shyjan AW, Gimeno CJ, Iris F, et al. Cloning and characterization of an uncoupling protein homolog: a potential molecular mediator of human thermogenesis. Diabetes 1997;46:900-906.
-
(1997)
Diabetes
, vol.46
, pp. 900-906
-
-
Gimeno, R.E.1
Dembski, M.2
Weng, X.3
Deng, N.4
Shyjan, A.W.5
Gimeno, C.J.6
Iris, F.7
-
16
-
-
18244379331
-
Superoxide activates mitochondrial uncoupling proteins
-
Echtay KS, Roussel D, St-Pierre J, Jekabsons MB, Cadenas S, Stuart JA, Harper JA, et al. Superoxide activates mitochondrial uncoupling proteins. Nature 2002;415:96-99.
-
(2002)
Nature
, vol.415
, pp. 96-99
-
-
Echtay, K.S.1
Roussel, D.2
St-Pierre, J.3
Jekabsons, M.B.4
Cadenas, S.5
Stuart, J.A.6
Harper, J.A.7
-
17
-
-
0041465009
-
A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling
-
Echtay KS, Esteves TC, Pakay JL, Jekabsons MB, Lambert AJ, Portero-Otin M, Pamplona R, et al. A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling. EMBO J 2003;22:4103-4110.
-
(2003)
EMBO J
, vol.22
, pp. 4103-4110
-
-
Echtay, K.S.1
Esteves, T.C.2
Pakay, J.L.3
Jekabsons, M.B.4
Lambert, A.J.5
Portero-Otin, M.6
Pamplona, R.7
-
18
-
-
0033969421
-
Uncoupling Proteins 2 and 3. Potential regulators of mitochondrial energy metabolism
-
Boss O, Hagen T, Lowell BB. Uncoupling Proteins 2 and 3. Potential regulators of mitochondrial energy metabolism. Diabetes 2000;49:149-156.
-
(2000)
Diabetes
, vol.49
, pp. 149-156
-
-
Boss, O.1
Hagen, T.2
Lowell, B.B.3
-
19
-
-
0037253404
-
The "novel" uncoupling proteins UCP2 and UCP3: What do they really do? Pros and cons for suggested functions
-
Nedergaard J, Cannon B. The "novel" uncoupling proteins UCP2 and UCP3: What do they really do? Pros and cons for suggested functions. Exp Physiol 2003;88:65-84.
-
(2003)
Exp Physiol
, vol.88
, pp. 65-84
-
-
Nedergaard, J.1
Cannon, B.2
-
20
-
-
0037039366
-
A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2
-
Krauss S, Zhang CY, Lowell BB. A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2. Proc Natl Acad Sci U S A 2002;99:118-122.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 118-122
-
-
Krauss, S.1
Zhang, C.Y.2
Lowell, B.B.3
-
21
-
-
0038061012
-
A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation
-
Negre-Salvayre A, Hirtz C, Carrera G, Cazenave R, Troly M, Salvayre R, Penicaud L, et al. A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation. FASEB J 1999;11:809-815.
-
(1999)
FASEB J
, vol.11
, pp. 809-815
-
-
Negre-Salvayre, A.1
Hirtz, C.2
Carrera, G.3
Cazenave, R.4
Troly, M.5
Salvayre, R.6
Penicaud, L.7
-
22
-
-
0036965865
-
Increased reactive oxygen species production with antisense oligonucleotides directed against uncoupling protein 2 in murine endothelial cells
-
Duval C, Negre-Salvayre A, Dogilo A, Salvayre R, Penicaud L, Casteilla L. Increased reactive oxygen species production with antisense oligonucleotides directed against uncoupling protein 2 in murine endothelial cells. Biochem Cell Biol 2002;80:757-764.
-
(2002)
Biochem Cell Biol
, vol.80
, pp. 757-764
-
-
Duval, C.1
Negre-Salvayre, A.2
Dogilo, A.3
Salvayre, R.4
Penicaud, L.5
Casteilla, L.6
-
23
-
-
0033667705
-
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
-
Arsenijevic D, Onuma H, Pecqueur C, Raimbault S, Manning BS, Miroux B, Couplan E, et al. Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat Genet 2000;26:435-439.
-
(2000)
Nat Genet
, vol.26
, pp. 435-439
-
-
Arsenijevic, D.1
Onuma, H.2
Pecqueur, C.3
Raimbault, S.4
Manning, B.S.5
Miroux, B.6
Couplan, E.7
-
24
-
-
0041464712
-
Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma
-
Mattiasson G, Shamloo M, Gido G, Mathi K, Tomasevic G, Yi S, Warden CH, et al. Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma. Nat Med 2003;9:1062-1068.
-
(2003)
Nat Med
, vol.9
, pp. 1062-1068
-
-
Mattiasson, G.1
Shamloo, M.2
Gido, G.3
Mathi, K.4
Tomasevic, G.5
Yi, S.6
Warden, C.H.7
-
25
-
-
0042526012
-
Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes
-
Teshima Y, Akao M, Jones SP, Marban E. Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes. Circ Res 2003;93:192-200.
-
(2003)
Circ Res
, vol.93
, pp. 192-200
-
-
Teshima, Y.1
Akao, M.2
Jones, S.P.3
Marban, E.4
-
26
-
-
18744428292
-
Kupffer cells are a dominant site of uncoupling protein 2 expression in rat liver
-
Larrouy D, Laharrague P, Carrera G, Viguerie-Bascands N, Levi-Meyrueis C, Fleury C, Pecqueur C, et al. Kupffer cells are a dominant site of uncoupling protein 2 expression in rat liver. Biochem Biophys Res Commun 1998;235:760-764.
-
(1998)
Biochem Biophys Res Commun
, vol.235
, pp. 760-764
-
-
Larrouy, D.1
Laharrague, P.2
Carrera, G.3
Viguerie-Bascands, N.4
Levi-Meyrueis, C.5
Fleury, C.6
Pecqueur, C.7
-
27
-
-
20644466225
-
Tumor necrosis factor increases mitochondrial oxidant production and induces expression of uncoupling protein-2 in the regenerating mice [correction of rat] liver
-
Lee FY, Li Y, Zhu H, Yang S, Lin HZ, Trush M, Diehl AM. Tumor necrosis factor increases mitochondrial oxidant production and induces expression of uncoupling protein-2 in the regenerating mice [correction of rat] liver. HEPATOLOGY 1999;29:677-687.
-
(1999)
Hepatology
, vol.29
, pp. 677-687
-
-
Lee, F.Y.1
Li, Y.2
Zhu, H.3
Yang, S.4
Lin, H.Z.5
Trush, M.6
Diehl, A.M.7
-
28
-
-
0032898080
-
Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver
-
Rashid A, Wu TC, Huang CC, Chen CH, Lin HZ, Yang SQ, Lee FY, et al. Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver. HEPATOLOGY 1999;29:1131-1138.
-
(1999)
Hepatology
, vol.29
, pp. 1131-1138
-
-
Rashid, A.1
Wu, T.C.2
Huang, C.C.3
Chen, C.H.4
Lin, H.Z.5
Yang, S.Q.6
Lee, F.Y.7
-
29
-
-
0033605261
-
Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion
-
Chavin KD, Yang S, Lin HZ, Chatham J, Chacko VP, Hoek JB, Walajtys-Rode E, et al. Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion. J Biol Chem 1999;274:5692-5700.
-
(1999)
J Biol Chem
, vol.274
, pp. 5692-5700
-
-
Chavin, K.D.1
Yang, S.2
Lin, H.Z.3
Chatham, J.4
Chacko, V.P.5
Hoek, J.B.6
Walajtys-Rode, E.7
-
30
-
-
0036207189
-
Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2
-
Baffy G, Zhang CY, Glickman JN, Lowell BB. Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2. HEPATOLOGY 2002;35:753-761.
-
(2002)
Hepatology
, vol.35
, pp. 753-761
-
-
Baffy, G.1
Zhang, C.Y.2
Glickman, J.N.3
Lowell, B.B.4
-
31
-
-
0035875087
-
Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes
-
Zhang C, Baffy G, Perret P, Krauss S, Peroni O, Grujic D, Hagen T, et al. Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes. Cell 2001;105:745-755.
-
(2001)
Cell
, vol.105
, pp. 745-755
-
-
Zhang, C.1
Baffy, G.2
Perret, P.3
Krauss, S.4
Peroni, O.5
Grujic, D.6
Hagen, T.7
-
33
-
-
0025814980
-
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
-
Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 1991;11:81-128.
-
(1991)
Free Radic Biol Med
, vol.11
, pp. 81-128
-
-
Esterbauer, H.1
Schaur, R.J.2
Zollner, H.3
-
34
-
-
0032576632
-
p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases
-
Medema RH, Klompmaker R, Smits VA, Rijksen G. p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases. Oncogene 1998;16:431-441.
-
(1998)
Oncogene
, vol.16
, pp. 431-441
-
-
Medema, R.H.1
Klompmaker, R.2
Smits, V.A.3
Rijksen, G.4
-
35
-
-
0033564697
-
CDK inhibitors: Positive and negative regulators of G1-phase progression
-
Sherr CJ, Roberts JM. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 1999;13:1501-1512.
-
(1999)
Genes Dev
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
36
-
-
0030067581
-
Targeted in vivo expression of the cyclin-dependent kinase inhibitor p21 halts hepatocyte cell-cycle progression, postnatal liver development and regeneration
-
Wu H, Wade M, Krall L, Grisham J, Xiong Y, Van Dyke T. Targeted in vivo expression of the cyclin-dependent kinase inhibitor p21 halts hepatocyte cell-cycle progression, postnatal liver development and regeneration. Genes Dev 1996;10:245-260.
-
(1996)
Genes Dev
, vol.10
, pp. 245-260
-
-
Wu, H.1
Wade, M.2
Krall, L.3
Grisham, J.4
Xiong, Y.5
Van Dyke, T.6
-
37
-
-
0029786329
-
Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway
-
Lavoie JN, L'Allemain G, Brunet A, Muller R, Pouyssegur J. Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. J Biol Chem 1996;271:20608-20616.
-
(1996)
J Biol Chem
, vol.271
, pp. 20608-20616
-
-
Lavoie, J.N.1
L'Allemain, G.2
Brunet, A.3
Muller, R.4
Pouyssegur, J.5
-
38
-
-
0035937856
-
Uncoupling protein 2, in vivo distribution, induction upon oxidative stress, and evidence for translational regulation
-
Pecqueur C, Alves-Guerra MC, Gelly C, Levi-Meyrueis C, Couplan E, Collins S, Ricquier D, et al. Uncoupling protein 2, in vivo distribution, induction upon oxidative stress, and evidence for translational regulation. J Biol Chem 2001;276:8705-8712.
-
(2001)
J Biol Chem
, vol.276
, pp. 8705-8712
-
-
Pecqueur, C.1
Alves-Guerra, M.C.2
Gelly, C.3
Levi-Meyrueis, C.4
Couplan, E.5
Collins, S.6
Ricquier, D.7
-
39
-
-
0009912839
-
Phenotypic abnormalities in macrophages from leptin-deficient, obese mice
-
Lee FY, Li Y, Yang EK, Yang SQ, Lin HZ, Trush MA, Dannenberg AJ, et al. Phenotypic abnormalities in macrophages from leptin-deficient, obese mice. Am J Physiol 1999;276:C386-394.
-
(1999)
Am J Physiol
, vol.276
-
-
Lee, F.Y.1
Li, Y.2
Yang, E.K.3
Yang, S.Q.4
Lin, H.Z.5
Trush, M.A.6
Dannenberg, A.J.7
-
40
-
-
0036905051
-
Expression of uncoupling protein-2 in biliary epithelial cells in primary biliary cirrhosis
-
Taniguchi E, Harada M, Kawaguchi T, Koga H, Kumemura H, Hanada S, Shishido S, et al. Expression of uncoupling protein-2 in biliary epithelial cells in primary biliary cirrhosis. Liver 2002;22:451-458.
-
(2002)
Liver
, vol.22
, pp. 451-458
-
-
Taniguchi, E.1
Harada, M.2
Kawaguchi, T.3
Koga, H.4
Kumemura, H.5
Hanada, S.6
Shishido, S.7
-
41
-
-
0032959236
-
Lipids up-regulate uncoupling protein 2 expression in rat hepatocytes
-
Cortez-Pinto H, Zhi Lin H, Qi Yang S, Odwin Da Costa S, Diehl AM. Lipids up-regulate uncoupling protein 2 expression in rat hepatocytes. Gastroenterology 1999;116:1184-1193.
-
(1999)
Gastroenterology
, vol.116
, pp. 1184-1193
-
-
Cortez-Pinto, H.1
Zhi Lin, H.2
Qi Yang, S.3
Odwin Da Costa, S.4
Diehl, A.M.5
-
42
-
-
0032837884
-
Partial hepatectomy and/or surgical stress provoke changes in the expression of lipoprotein lipase and actin in liver and extrahepatic tissues
-
Palmero E, Ricart D, Llobera M, Peinado-Onsurbe J. Partial hepatectomy and/or surgical stress provoke changes in the expression of lipoprotein lipase and actin in liver and extrahepatic tissues. Biochim Biophys Acta 1999;1441:61-68.
-
(1999)
Biochim Biophys Acta
, vol.1441
, pp. 61-68
-
-
Palmero, E.1
Ricart, D.2
Llobera, M.3
Peinado-Onsurbe, J.4
-
43
-
-
0036862006
-
Ethanol induces redox-sensitive cell-cycle inhibitors and inhibits liver regeneration after partial hepatectomy
-
Koteish A, Yang S, Lin H, Huang, Diehl AM. Ethanol induces redox-sensitive cell-cycle inhibitors and inhibits liver regeneration after partial hepatectomy. Alcohol Clin Exp Res 2002;26:1710-1718.
-
(2002)
Alcohol Clin Exp Res
, vol.26
, pp. 1710-1718
-
-
Koteish, A.1
Yang, S.2
Lin, H.3
Huang4
Diehl, A.M.5
-
44
-
-
0036314662
-
STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers
-
Torbenson M, Yang SQ, Liu HZ, Huang J, Gage W, Diehl AM. STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers. Am J Pathol 2002;161:155-161.
-
(2002)
Am J Pathol
, vol.161
, pp. 155-161
-
-
Torbenson, M.1
Yang, S.Q.2
Liu, H.Z.3
Huang, J.4
Gage, W.5
Diehl, A.M.6
-
45
-
-
0032515194
-
Transformed but not normal hepatocytes express UCP2
-
Carretero MV, Torres L, Latasa U, Garcia-Trevijano ER, Prieto J, Mato JM, Avila MA. Transformed but not normal hepatocytes express UCP2. FEBS Lett 1998;439:55-58.
-
(1998)
FEBS Lett
, vol.439
, pp. 55-58
-
-
Carretero, M.V.1
Torres, L.2
Latasa, U.3
Garcia-Trevijano, E.R.4
Prieto, J.5
Mato, J.M.6
Avila, M.A.7
|