SCOPUS 정보 검색 플랫폼

Volumn 2, Issue 5, 2007, Pages 641-654

Synthesis, biological evaluation, and molecular modeling investigation of chiral phenoxyacetic acid analogues with PPARα and PPARγ agonist activity

(9) Fracchiolla, Giuseppe a Laghezza, Antonio a Piemontese, Luca a Carbonara, Giuseppe a Lavecchia, Antonio b Tortorella, Paolo a Crestani, Maurizio c Novellino, Ettore b Loiodice, Fulvio a

a UNIVERSITY OF BARI (Italy)

b UNIVERSITY OF NAPLES FEDERICO II (Italy)

c UNIVERSITY OF MILAN (Italy)

Author keywords

Chirality; Molecular modeling; Peroxisome proliferator activated receptors

Indexed keywords

ACETIC ACID DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHENOXYACETIC ACID;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG POTENTIATION; HUMAN; STEREOISOMERISM; SYNTHESIS; TUMOR CELL LINE;

ACETIC ACIDS; CELL LINE, TUMOR; HUMANS; MODELS, MOLECULAR; PPAR ALPHA; PPAR GAMMA; STEREOISOMERISM;

EID: 34848833429 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200600307 Document Type: Article

Times cited : (32)

References (59)

1
- 0035856920
- P. Z. Zimmet, K. G. M. M. Alberti, J. Shaw, Nature 2001, 414, 782-787.
- (2001) Nature , vol.414 , pp. 782-787
- Zimmet, P.Z.¹ Alberti, K.G.M.M.² Shaw, J.³

2
- 0028318013
- B. Hulin, Prog. Med. Chem. 1994, 31, 1-58.
- (1994) Prog. Med. Chem , vol.31 , pp. 1-58
- Hulin, B.¹

3
- 0036001044
- M. H. Moneva, S. Dagogo-Jack, Curr. Drug Targets 2002, 3, 203-221.
- (2002) Curr. Drug Targets , vol.3 , pp. 203-221
- Moneva, M.H.¹ Dagogo-Jack, S.²

4
- 3843116771
- and references therein
- J. S. Skyler, J. Med. Chem. 2004, 47, 4113-4117, and references therein.
- (2004) J. Med. Chem , vol.47 , pp. 4113-4117
- Skyler, J.S.¹

5
- 0033574663
- Nuclear Receptor Nomenclature Committee
- Nuclear Receptor Nomenclature Committee, Cell 1999, 97, 161-163.
- (1999) Cell , vol.97 , pp. 161-163

6
- 0036183630
- J. Berger, D. E. Moller, Annu. Rev. Med. 2002, 53, 409-435.
- (2002) Annu. Rev. Med , vol.53 , pp. 409-435
- Berger, J.¹ Moller, D.E.²

7
- 0030985318
- G. Krey, O. Braissant, F. L'Horset, E. Kalkhoven, M. Perroud, M. G. Parker, W. Wahli, Mol. Endocrinol. 1997, 11, 779-791.
- (1997) Mol. Endocrinol , vol.11 , pp. 779-791
- Krey, G.¹ Braissant, O.² L'Horset, F.³ Kalkhoven, E.⁴ Perroud, M.⁵ Parker, M.G.⁶ Wahli, W.⁷

8
- 0032506273
- B. Staels, J. Dallongeville, J. Auwerx, K. Schoonjans, E. Leitersdorf, J.-C. Fruchart, Circulation 1998, 98, 2088-2093.
- (1998) Circulation , vol.98 , pp. 2088-2093
- Staels, B.¹ Dallongeville, J.² Auwerx, J.³ Schoonjans, K.⁴ Leitersdorf, E.⁵ Fruchart, J.-C.⁶

9
- 0032816777
- J.-C. Fruchart, P. Duriez, B. Staels, Curr. Opin. Lipidol. 1999, 10, 245-257.
- (1999) Curr. Opin. Lipidol , vol.10 , pp. 245-257
- Fruchart, J.-C.¹ Duriez, P.² Staels, B.³

10
- 0030062325
- T. M. Willson, J. E. Cobb, D. J. Cowan, R. W. Wiethe, I. D. Correa, S. R. Prakash, K. D. Beck, L. B. Moore, S. A. Kliewer, J. M. Lehmann, J. Med. Chem. 1996, 39, 665-668.
- (1996) J. Med. Chem , vol.39 , pp. 665-668
- Willson, T.M.¹ Cobb, J.E.² Cowan, D.J.³ Wiethe, R.W.⁴ Correa, I.D.⁵ Prakash, S.R.⁶ Beck, K.D.⁷ Moore, L.B.⁸ Kliewer, S.A.⁹ Lehmann, J.M.¹⁰

11
- 0035431321
- P. Cronet, J. F. W. Petersen, R. Folmer, N. Blomberg, K. Sjöblom, U. Karlsson, E.-L. Lindstedt, K. Bamberg, Structure 2001, 9, 699-706.
- (2001) Structure , vol.9 , pp. 699-706
- Cronet, P.¹ Petersen, J.F.W.² Folmer, R.³ Blomberg, N.⁴ Sjöblom, K.⁵ Karlsson, U.⁶ Lindstedt, E.-L.⁷ Bamberg, K.⁸

12
- 0035927439
- D. A. Brooks, G. J. Etgen, C. J. Rito, A. Shuker, S. J. Dominianni, A. M. Warshawsky, R. Ardecky, J. R. Paterniti, J. Tyhonas, D. S. Karanewsky, R. F. Kauffman, C. L. Broderick, B. A. Oldham, C. Montrose-Rafizadeh, L. L. Winneroski, M. M. Faul, J. R. McCarthy, J. Med. Chem. 2001, 44, 2061-2064.
- (2001) J. Med. Chem , vol.44 , pp. 2061-2064
- Brooks, D.A.¹ Etgen, G.J.² Rito, C.J.³ Shuker, A.⁴ Dominianni, S.J.⁵ Warshawsky, A.M.⁶ Ardecky, R.⁷ Paterniti, J.R.⁸ Tyhonas, J.⁹ Karanewsky, D.S.¹⁰ Kauffman, R.F.¹¹ Broderick, C.L.¹² Oldham, B.A.¹³ Montrose-Rafizadeh, C.¹⁴ Winneroski, L.L.¹⁵ Faul, M.M.¹⁶ McCarthy, J.R.¹⁷

13
- 0035797363
- B. B. Lohray, V. B. Lohray, A. C. Bajji, S. Kalchar, R. R. Poondra, S. Padakanti, R. Chakrabarti, R. K. Vikramadithyan, P. Misra, S. Juluri, N. V. S. R. Mamidi, R. Rajagopalan, J. Med. Chem. 2001, 44, 2675-2678.
- (2001) J. Med. Chem , vol.44 , pp. 2675-2678
- Lohray, B.B.¹ Lohray, V.B.² Bajji, A.C.³ Kalchar, S.⁴ Poondra, R.R.⁵ Padakanti, S.⁶ Chakrabarti, R.⁷ Vikramadithyan, R.K.⁸ Misra, P.⁹ Juluri, S.¹⁰ Mamidi, N.V.S.R.¹¹ Rajagopalan, R.¹²

14
- 0037075146
- P. Sauerberg, I. Pettersson, L. Jeppesen, P. S. Bury, J. P. Mogensen, K. Wassermann, C. L. Brand, J. Sturis, H. F. Wöldike, J. Fleckner, A.-S. T. Andersen, S. B. Mortensen, L. A. Svensson, H. B. Rasmussen, S. V. Lehmann, Z. Polivka, K. Sindelar, V. Panajotova, L. Ynddal, E. M. Wulff, J. Med. Chem. 2002, 45, 789-804.
- (2002) J. Med. Chem , vol.45 , pp. 789-804
- Sauerberg, P.¹ Pettersson, I.² Jeppesen, L.³ Bury, P.S.⁴ Mogensen, J.P.⁵ Wassermann, K.⁶ Brand, C.L.⁷ Sturis, J.⁸ Wöldike, H.F.⁹ Fleckner, J.¹⁰ Andersen, A.-S.T.¹¹ Mortensen, S.B.¹² Svensson, L.A.¹³ Rasmussen, H.B.¹⁴ Lehmann, S.V.¹⁵ Polivka, Z.¹⁶ Sindelar, K.¹⁷ Panajotova, V.¹⁸ Ynddal, L.¹⁹ Wulff, E.M.²⁰ more..

15
- 0036224780
- G. J. Etgen, B. A. Oldham, W. T. Johnson, C. L. Broderick, C. R. Montrose, J. T. Brozinick, E. A. Misener, J. S. Bean, W. R. Bensch, D. A. Brooks, A. J. Shuker, C. A. Rito, J. R. McCarthy, R. A. Ardecky, J. S. Tyhonas, S. L. Dana, J. M. Bilakovics, J. R. Paterniti Jr., K. M. Ogilvie, S. Liu, R. F. Kauffman, Diabetes 2002, 51, 1083-1087.
- (2002) Diabetes , vol.51 , pp. 1083-1087
- Etgen, G.J.¹ Oldham, B.A.² Johnson, W.T.³ Broderick, C.L.⁴ Montrose, C.R.⁵ Brozinick, J.T.⁶ Misener, E.A.⁷ Bean, J.S.⁸ Bensch, W.R.⁹ Brooks, D.A.¹⁰ Shuker, A.J.¹¹ Rito, C.A.¹² McCarthy, J.R.¹³ Ardecky, R.A.¹⁴ Tyhonas, J.S.¹⁵ Dana, S.L.¹⁶ Bilakovics, J.M.¹⁷ Paterniti Jr., J.R.¹⁸ Ogilvie, K.M.¹⁹ Liu, S.²⁰ Kauffman, R.F.²¹ more..

16
- 0037431401
- S. Ebdrup, I. Pettersson, H. B. Rasmussen, H.-J. Deussen, A. F. Jensen, S. B. Mortensen, J. Fleckner, L. Pridal, L. Nygaard, P. Sauerberg, J. Med. Chem. 2003, 46, 1306-1317.
- (2003) J. Med. Chem , vol.46 , pp. 1306-1317
- Ebdrup, S.¹ Pettersson, I.² Rasmussen, H.B.³ Deussen, H.-J.⁴ Jensen, A.F.⁵ Mortensen, S.B.⁶ Fleckner, J.⁷ Pridal, L.⁸ Nygaard, L.⁹ Sauerberg, P.¹⁰

17
- 2342628600
- Y. Xu, C. J. Rito, G. J. Etgen, R. J. Ardecky, J. S. Bean, W. R. Bensch, J. R. Bosley, C. L. Broderick, D. A. Brooks, S. J. Dominianni, P. J. Hahn, S. Liu, D. E. Mais, C. Montrose-Rafizadeh, K. M. Ogilvie, B. A. Oldham, M. Peters, D. K. Rungta, A. J. Shuker, G. A. Stephenson, A. E. Tripp, S. B. Wilson, L. L. Winneroski, R. Zink, R. F. Kauffman, J. R. McCarthy, J. Med. Chem. 2004, 47, 2422-2425.
- (2004) J. Med. Chem , vol.47 , pp. 2422-2425
- Xu, Y.¹ Rito, C.J.² Etgen, G.J.³ Ardecky, R.J.⁴ Bean, J.S.⁵ Bensch, W.R.⁶ Bosley, J.R.⁷ Broderick, C.L.⁸ Brooks, D.A.⁹ Dominianni, S.J.¹⁰ Hahn, P.J.¹¹ Liu, S.¹² Mais, D.E.¹³ Montrose-Rafizadeh, C.¹⁴ Ogilvie, K.M.¹⁵ Oldham, B.A.¹⁶ Peters, M.¹⁷ Rungta, D.K.¹⁸ Shuker, A.J.¹⁹ Stephenson, G.A.²⁰ more..

18
- 2542612265
- H. Koyama, D. J. Miller, J. K. Boueres, R. C. Desai, B. Jones, J. P. Berger, K. L. MacNaul, L. J. Kelly, T. W. Doebber, M. S. Wu, G. Zhou, P. Wang, M. C. Ippolito, Y.-S. Chao, A. K. Agrawal, R. Franklin, J. V. Heck, S. D. Wright, D. E. Moller, S. P. Sahoo, J. Med. Chem. 2004, 47, 3255-3263.
- (2004) J. Med. Chem , vol.47 , pp. 3255-3263
- Koyama, H.¹ Miller, D.J.² Boueres, J.K.³ Desai, R.C.⁴ Jones, B.⁵ Berger, J.P.⁶ MacNaul, K.L.⁷ Kelly, L.J.⁸ Doebber, T.W.⁹ Wu, M.S.¹⁰ Zhou, G.¹¹ Wang, P.¹² Ippolito, M.C.¹³ Chao, Y.-S.¹⁴ Agrawal, A.K.¹⁵ Franklin, R.¹⁶ Heck, J.V.¹⁷ Wright, S.D.¹⁸ Moller, D.E.¹⁹ Sahoo, S.P.²⁰ more..

19
- 11144354267
- M. Takamura, M. Sakurai, E. Yamada, S. Fujita, M. Yachi, T. Takagi, A. Isobe, Y. Hagisawa, T. Fujiwara, H. Yanagisawa, Bioorg. Med. Chem. 2004, 12, 2419-2439.
- (2004) Bioorg. Med. Chem , vol.12 , pp. 2419-2439
- Takamura, M.¹ Sakurai, M.² Yamada, E.³ Fujita, S.⁴ Yachi, M.⁵ Takagi, T.⁶ Isobe, A.⁷ Hagisawa, Y.⁸ Fujiwara, T.⁹ Yanagisawa, H.¹⁰

20
- 0031793850
- K. Murakami, K. Tobe, T. Ide, T. Mochizuki, M. Ohashi, Y. Akanuma, Y. Yazaki, T. Kadowaki, Diabetes 1998, 47, 1841-1847.
- (1998) Diabetes , vol.47 , pp. 1841-1847
- Murakami, K.¹ Tobe, K.² Ide, T.³ Mochizuki, T.⁴ Ohashi, M.⁵ Akanuma, Y.⁶ Yazaki, Y.⁷ Kadowaki, T.⁸

21
- 0035801724
- K. G. Liu, J. S. Smith, A. H. Ayscue, B. R. Henke, M. H. Lambert, L. M. Leesnitzer, K. D. Plunket, T. M. Willson, D. D. Sternbach, Bioorg. Med. Chem. Lett. 2001, 11, 2385-2388.
- (2001) Bioorg. Med. Chem. Lett , vol.11 , pp. 2385-2388
- Liu, K.G.¹ Smith, J.S.² Ayscue, A.H.³ Henke, B.R.⁴ Lambert, M.H.⁵ Leesnitzer, L.M.⁶ Plunket, K.D.⁷ Willson, T.M.⁸ Sternbach, D.D.⁹

22
- 0033998334
- T. M. Willson, P. J. Brown, D. D. Sternbach, B. R. Henke, J. Med. Chem. 2000, 43, 527-550.
- (2000) J. Med. Chem , vol.43 , pp. 527-550
- Willson, T.M.¹ Brown, P.J.² Sternbach, D.D.³ Henke, B.R.⁴

23
- 23944473582
- A. Pinelli, C. Godio, A. Laghezza, N. Mitro, G. Fracchiolla, V. Tortorella, A. Lavecchia, E. Novellino, J.-C. Fruchart, B. Staels, M. Crestani, F. Loiodice, J. Med. Chem. 2005, 48, 5509-5519.
- (2005) J. Med. Chem , vol.48 , pp. 5509-5519
- Pinelli, A.¹ Godio, C.² Laghezza, A.³ Mitro, N.⁴ Fracchiolla, G.⁵ Tortorella, V.⁶ Lavecchia, A.⁷ Novellino, E.⁸ Fruchart, J.-C.⁹ Staels, B.¹⁰ Crestani, M.¹¹ Loiodice, F.¹²

24
- 54849415650
- J. Shoichi, Y. Yoshiaki, O. Takayuki, O. Shinji Jpn. Kokai Tokyo Koho, Jpn. Appl. 02193942, 1990 [Chem. Abstr. 1990, 113, 211 579
- J. Shoichi, Y. Yoshiaki, O. Takayuki, O. Shinji (Jpn. Kokai Tokyo Koho), Jpn. Appl. 02193942, 1990 [Chem. Abstr. 1990, 113, 211 579].

25
- 0035444429
- G. Carbonara, G. Fracchiolla, F. Loiodice, P. Tortorella, D. Conte-Camerino, A. M. De Luca, A. Liantonio, Farmaco 2001, 56, 749-754.
- (2001) Farmaco , vol.56 , pp. 749-754
- Carbonara, G.¹ Fracchiolla, G.² Loiodice, F.³ Tortorella, P.⁴ Conte-Camerino, D.⁵ De Luca, A.M.⁶ Liantonio, A.⁷

26
- 0038939958
- C. K. Lau, S. Tardif, C. Dufresne, J. Scheigetz, J. Org. Chem. 1989, 54, 491-494.
- (1989) J. Org. Chem , vol.54 , pp. 491-494
- Lau, C.K.¹ Tardif, S.² Dufresne, C.³ Scheigetz, J.⁴

27
- 85077634689
- O. Mitsunobu, Synthesis 1981, 1-28.
- (1981) Synthesis , pp. 1-28
- Mitsunobu, O.¹

28
- 0028065056
- K. Koh, T. Durst, J. Org. Chem. 1994, 59, 4683-4686.
- (1994) J. Org. Chem , vol.59 , pp. 4683-4686
- Koh, K.¹ Durst, T.²

29
- 0035801815
- D. J. Reynolds, S. A. Hermitage, Tetrahedron 2001, 57, 7765-7770.
- (2001) Tetrahedron , vol.57 , pp. 7765-7770
- Reynolds, D.J.¹ Hermitage, S.A.²

30
- 0037060923
- G. A. Doherty, T. Kamenecka, E. McCauley, G. Van Riper, R. A. Mumford, S. Tong, W. K. Hagmann, Bioorg. Med. Chem. Lett. 2002, 12, 729-731.
- (2002) Bioorg. Med. Chem. Lett , vol.12 , pp. 729-731
- Doherty, G.A.¹ Kamenecka, T.² McCauley, E.³ Van Riper, G.⁴ Mumford, R.A.⁵ Tong, S.⁶ Hagmann, W.K.⁷

31
- 0033790625
- S. Ferorelli, F. Loiodice, A. Longo, A. Molfetta, V. Tortorella, R. Amoroso, Chirality 2000, 12, 697-704.
- (2000) Chirality , vol.12 , pp. 697-704
- Ferorelli, S.¹ Loiodice, F.² Longo, A.³ Molfetta, A.⁴ Tortorella, V.⁵ Amoroso, R.⁶

32
- 12444272240
- A. Liantonio, A. De Luca, S. Pierno, M. P. Didonna, F. Loiodice, G. Fracchiolla, P. Tortorella, A. Laghezza, E. Bonerba, S. Traverso, L. Elia, A. Picollo, M. Pusch, D. Conte Camerino, Br. J. Pharmacol. 2003, 139, 1255-1264.
- (2003) Br. J. Pharmacol , vol.139 , pp. 1255-1264
- Liantonio, A.¹ De Luca, A.² Pierno, S.³ Didonna, M.P.⁴ Loiodice, F.⁵ Fracchiolla, G.⁶ Tortorella, P.⁷ Laghezza, A.⁸ Bonerba, E.⁹ Traverso, S.¹⁰ Elia, L.¹¹ Picollo, A.¹² Pusch, M.¹³ Conte Camerino, D.¹⁴

33
- 0002547716
- G. N. Walker, R. T. Smith, J. Org. Chem. 1971, 36, 305-308.
- (1971) J. Org. Chem , vol.36 , pp. 305-308
- Walker, G.N.¹ Smith, R.T.²

34
- 0024844427
- R. R. Soni, K. N. Trivedi, Pharmazie 1989, 44, 760-762.
- (1989) Pharmazie , vol.44 , pp. 760-762
- Soni, R.R.¹ Trivedi, K.N.²

35
- 0029016829
- J. M. Lehmann, L. B. Moore, T. A. Smith-Oliver, W. O. Wilkison, T. M. Willson, S. A. Kliewer, J. Biol. Chem. 1995, 270, 12953-12956.
- (1995) J. Biol. Chem , vol.270 , pp. 12953-12956
- Lehmann, J.M.¹ Moore, L.B.² Smith-Oliver, T.A.³ Wilkison, W.O.⁴ Willson, T.M.⁵ Kliewer, S.A.⁶

36
- 0035923672
- H. E. Xu, M. H. Lambert, V. G. Montana, K. D. Plunket, L. B. Moore, J. L. Collins, J. A. Oplinger, S. A. Kliewer, R. T. Gampe, Jr., D. D. McKee, J. T. Moore, T. M. Willson, J. B. Stimmel, Proc. Natl. Acad. Sci. USA 2001, 98, 13919-13924.
- (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 13919-13924
- Xu, H.E.¹ Lambert, M.H.² Montana, V.G.³ Plunket, K.D.⁴ Moore, L.B.⁵ Collins, J.L.⁶ Oplinger, J.A.⁷ Kliewer, S.A.⁸ Gampe Jr., R.T.⁹ McKee, D.D.¹⁰ Moore, J.T.¹¹ Willson, T.M.¹² Stimmel, J.B.¹³

37
- 0023936327
- R. L. DesJarlais, R. P. Sheridan, G. L. Seibel, J. S. Dixon, I. D. Kuntz, R. Venkataraghavan, J. Med. Chem. 1988, 31, 722-729.
- (1988) J. Med. Chem , vol.31 , pp. 722-729
- DesJarlais, R.L.¹ Sheridan, R.P.² Seibel, G.L.³ Dixon, J.S.⁴ Kuntz, I.D.⁵ Venkataraghavan, R.⁶

38
- 0030111106
- D. A. Gschwend, A. C. Good, I. D. Kuntz, J. Mol. Recognit. 1996, 9, 175-186.
- (1996) J. Mol. Recognit , vol.9 , pp. 175-186
- Gschwend, D.A.¹ Good, A.C.² Kuntz, I.D.³

39
- 0026730489
- I. D. Kuntz, Science 1992, 257, 1078-1082.
- (1992) Science , vol.257 , pp. 1078-1082
- Kuntz, I.D.¹

40
- 0032505096
- R. T. Nolte, G. B. Wisely, S. Westin, J. E. Cobb, M. H. Lambert, R. Kurokawa, M. G. Rosenfeld, T. M. Willson, C. K. Glass, M. V. Milburn, Nature 1998, 395, 137-143.
- (1998) Nature , vol.395 , pp. 137-143
- Nolte, R.T.¹ Wisely, G.B.² Westin, S.³ Cobb, J.E.⁴ Lambert, M.H.⁵ Kurokawa, R.⁶ Rosenfeld, M.G.⁷ Willson, T.M.⁸ Glass, C.K.⁹ Milburn, M.V.¹⁰

41
- 0033681001
- R. T. Gampe, V. G. Montana, M. H. Lambert, A. B. Miller, R. K. Bledsoe, M. V. Milburn, S. A. Kliewer, T. M. Willson, H. E. Xu, Mol. Cell 2000, 5, 545-555.
- (2000) Mol. Cell , vol.5 , pp. 545-555
- Gampe, R.T.¹ Montana, V.G.² Lambert, M.H.³ Miller, A.B.⁴ Bledsoe, R.K.⁵ Milburn, M.V.⁶ Kliewer, S.A.⁷ Willson, T.M.⁸ Xu, H.E.⁹

42
- 0032553542
- J. Uppenberg, C. Svensson, M. Jaki, G. Bertilsson, L. Jendeberg, A. Berkenstam, J. Biol. Chem. 1998, 273, 31108-31112.
- (1998) J. Biol. Chem , vol.273 , pp. 31108-31112
- Uppenberg, J.¹ Svensson, C.² Jaki, M.³ Bertilsson, G.⁴ Jendeberg, L.⁵ Berkenstam, A.⁶

43
- 0032740190
- E. Raspe, L. Madsen, A.-M. Lefebvre, I. Leitersdorf, L. Gelman, J. Peinado-Onsurbe, J. Dallongeville, J.-C. Fruchart, R. Berge, B. Staels, J. Lipid Res. 1999, 40, 2099-2110.
- (1999) J. Lipid Res , vol.40 , pp. 2099-2110
- Raspe, E.¹ Madsen, L.² Lefebvre, A.-M.³ Leitersdorf, I.⁴ Gelman, L.⁵ Peinado-Onsurbe, J.⁶ Dallongeville, J.⁷ Fruchart, J.-C.⁸ Berge, R.⁹ Staels, B.¹⁰

44
- 0024448155
- T. Hollons, F. K. Yoshimura, Anal. Biochem. 1989, 182, 411-418.
- (1989) Anal. Biochem , vol.182 , pp. 411-418
- Hollons, T.¹ Yoshimura, F.K.²

45
- 54849430915
- SYBYL Molecular Modeling System (Version 7.1, TRIPOS Assoc, St. Louis, MO USA
- SYBYL Molecular Modeling System (Version 7.1), TRIPOS Assoc., St. Louis, MO (USA).

46
- 4444221565
- E. F. Pettersen, T. D. Goddard, C. C. Huang, G. S. Couch, D. M. Greenblatt, E. C. Meng, T. E. Ferrin, J. Comput. Chem. 2004, 25, 1605-1612.
- (2004) J. Comput. Chem , vol.25 , pp. 1605-1612
- Pettersen, E.F.¹ Goddard, T.D.² Huang, C.C.³ Couch, G.S.⁴ Greenblatt, D.M.⁵ Meng, E.C.⁶ Ferrin, T.E.⁷

47
- 0023325062
- J. G. Vinter, A. Davis, M. R. Saunders, J. Comput.-Aided Mol. Des. 1987, 1, 31-55.
- (1987) J. Comput.-Aided Mol. Des , vol.1 , pp. 31-55
- Vinter, J.G.¹ Davis, A.² Saunders, M.R.³

48
- 54849429102
- D. A. Case, T. A. Darden, T. E. Cheatham III, C. L. Simmerling, J. Wang, R. E. Duke, R. Luo, K. M. Merz, B. Wang, D. A. Pearlman, M. Crowley, S. Brozell, V. Tsui, H. Gohlke, J. Mongan, V. Hornak, G. Cui, P. Beroza, C. Schafmeister, J. W. Caldwell, W. S. Ross, P. A. Kollman, AMBER 8; University of California, San Francisco, 2004.
- D. A. Case, T. A. Darden, T. E. Cheatham III, C. L. Simmerling, J. Wang, R. E. Duke, R. Luo, K. M. Merz, B. Wang, D. A. Pearlman, M. Crowley, S. Brozell, V. Tsui, H. Gohlke, J. Mongan, V. Hornak, G. Cui, P. Beroza, C. Schafmeister, J. W. Caldwell, W. S. Ross, P. A. Kollman, AMBER 8; University of California, San Francisco, 2004.

49
- 0029011701
- W. D. Cornell, P. Cieplak, C. I. Bayly, I. R. Gould, K. M. Merz Jr., D. M. Ferguson, D. C. Spellmeyer, T. Fox, J. W. Caldwell, P. A. Kollman, J. Am. Chem. Soc. 1995, 117, 5179-5197.
- (1995) J. Am. Chem. Soc , vol.117 , pp. 5179-5197
- Cornell, W.D.¹ Cieplak, P.² Bayly, C.I.³ Gould, I.R.⁴ Merz Jr., K.M.⁵ Ferguson, D.M.⁶ Spellmeyer, D.C.⁷ Fox, T.⁸ Caldwell, J.W.⁹ Kollman, P.A.¹⁰

50
- 3343012886
- J. Head, M. C. Zerner, Chem. Phys. Lett. 1985, 122, 264-274.
- (1985) Chem. Phys. Lett , vol.122 , pp. 264-274
- Head, J.¹ Zerner, M.C.²

51
- 2942532422
- J. Wang, R. M. Wolf, J. W. Caldwell, P. A. Kollman, D. A. Case, J. Comput. Chem. 2004, 25, 1157-1174.
- (2004) J. Comput. Chem , vol.25 , pp. 1157-1174
- Wang, J.¹ Wolf, R.M.² Caldwell, J.W.³ Kollman, P.A.⁴ Case, D.A.⁵

52
- 0021107965
- M. L. Connolly, Science 1983, 221, 709-713.
- (1983) Science , vol.221 , pp. 709-713
- Connolly, M.L.¹

53
- 0020491251
- I. D. Kuntz, J. M. Blaney, S. J. Oatley, R. Langridge, T. E. Ferrin, J. Mol. Biol. 1982, 161, 269-288.
- (1982) J. Mol. Biol , vol.161 , pp. 269-288
- Kuntz, I.D.¹ Blaney, J.M.² Oatley, S.J.³ Langridge, R.⁴ Ferrin, T.E.⁵

54
- 84986518987
- B. Shoichet, D. Bodian, I. D. Kuntz, J. Comput. Chem. 1992, 13, 380-397.
- (1992) J. Comput. Chem , vol.13 , pp. 380-397
- Shoichet, B.¹ Bodian, D.² Kuntz, I.D.³

55
- 84986467005
- A. R. Leach, I. D. Kuntz, J. Comput. Chem. 1992, 13, 730-748.
- (1992) J. Comput. Chem , vol.13 , pp. 730-748
- Leach, A.R.¹ Kuntz, I.D.²

56
- 0002636134
- G. D. Hawkins, C. J. Cramer, D. G. Truhlar, Chem. Phys. Lett. 1995, 246, 122-129.
- (1995) Chem. Phys. Lett , vol.246 , pp. 122-129
- Hawkins, G.D.¹ Cramer, C.J.² Truhlar, D.G.³

57
- 33748390341
- G. D. Hawkins, C. J. Cramer, D. G. Truhlar, J. Phys. Chem. 1996, 100, 19824-19839.
- (1996) J. Phys. Chem , vol.100 , pp. 19824-19839
- Hawkins, G.D.¹ Cramer, C.J.² Truhlar, D.G.³

58
- 33750587438
- H. J. C. Berendsen, J. P. M. Postma, W. F. Vangunsteren, A. Dinola, J. R. Haak, J. Chem. Phys. 1984, 81, 3684-3690.
- (1984) J. Chem. Phys , vol.81 , pp. 3684-3690
- Berendsen, H.J.C.¹ Postma, J.P.M.² Vangunsteren, W.F.³ Dinola, A.⁴ Haak, J.R.⁵

59
- 33646940952
- J. P. Ryckaert, G. Ciccotti, H. J. C. Berendsen, J. Comput. Phys. 1977, 23, 327-341.
- (1977) J. Comput. Phys , vol.23 , pp. 327-341
- Ryckaert, J.P.¹ Ciccotti, G.² Berendsen, H.J.C.³

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.