N-aryl 2,6-dimethoxybiphenylalanine analogues as VLA-4 antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 5, 2002, Pages 729-731

  Doherty, George A ^a   Kamenecka, Theodore ^a   McCauley, Ermenegilda ^a   Van Riper, Gail ^a   Mumford, Richard A ^a   Tong, Sharon ^a   Hagmann, William K ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; INTEGRIN; PHENYLALANINE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROGEN BOND; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

INTEGRIN ALPHA4BETA1; INTEGRINS; MOLECULAR STRUCTURE; PHENYLALANINE; RECEPTORS, LYMPHOCYTE HOMING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037060923     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00009-4     Document Type: Article

References (15)