Carboxylic acids and skeletal muscle chloride channel conductance: Effects on the biological activity induced by the introduction of an aryloxyalkyl group α to the carboxylic function of 4-chloro-phenoxyacetic acid

Farmaco

Volumn 56, Issue 10, 2001, Pages 749-754

  Carbonara, Giuseppe ^a   Fracchiolla, Giuseppe ^a   Loiodice, Fulvio ^a   Tortorella, Paolo ^b   Conte Camerino, Diana ^a   De Luca, Annamaria ^a   Liantonio, Antonella ^a  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

Author keywords

Aryloxyalkanoic acids; Chloride channel conductance; Myotonic inducing effects; Rat skeletal muscle

Indexed keywords

2 (4 CHLOROPHENOXY)BUTANOIC ACID DERIVATIVE; 2 (4 CHLOROPHENOXY)PROPIONIC ACID; 4 CHLOROPHENOXYACETIC ACID; CARBOXYLIC ACID DERIVATIVE; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; CLOFIBRIC ACID DERIVATIVE; MEMBRANE RECEPTOR; METHYL GROUP; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHEMICAL MODIFICATION; CHIRALITY; CHLORIDE CONDUCTANCE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; EXTENSOR DIGITORUM LONGUS MUSCLE; MALE; MEMBRANE RESISTANCE; MEMBRANE STEADY POTENTIAL; MUSCLE FIBER MEMBRANE CONDUCTANCE; NONHUMAN; RAT; SKELETAL MUSCLE; STEREOCHEMISTRY;

2,4-DICHLOROPHENOXYACETIC ACID; ANIMALS; CARBOXYLIC ACIDS; CHLORIDE CHANNELS; CLOFIBRIC ACID; MALE; MUSCLE, SKELETAL; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035444429     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(01)01127-2     Document Type: Article

References (17)

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