-
1
-
-
34548837046
-
From defining bioinformatics and pharmacogenomics to developing information-based medicine and pharmacotyping in healthcare
-
Gad SC, editor, New York: John Wiley & Sons, Inc
-
Vizirianakis IS. From defining bioinformatics and pharmacogenomics to developing information-based medicine and pharmacotyping in healthcare. In: Gad SC, editor. Handbook of pharmaceutical biotechnology. New York: John Wiley & Sons, Inc., 2007: 201-28
-
(2007)
Handbook of pharmaceutical biotechnology
, pp. 201-228
-
-
Vizirianakis, I.S.1
-
2
-
-
0037421590
-
Pharmacogenomics: Drug disposition, drug targets, and side effects
-
Evans WE, McLeod HL. Pharmacogenomics: drug disposition, drug targets, and side effects. N Engl J Med 2003; 348: 538-49
-
(2003)
N Engl J Med
, vol.348
, pp. 538-549
-
-
Evans, W.E.1
McLeod, H.L.2
-
3
-
-
0035575568
-
Personalized medicine: Revolutionizing drug discovery and patient care
-
Ginsburg GS, McCarthy JJ. Personalized medicine: revolutionizing drug discovery and patient care. Trends Biotechnol 2001; 19: 491-6
-
(2001)
Trends Biotechnol
, vol.19
, pp. 491-496
-
-
Ginsburg, G.S.1
McCarthy, J.J.2
-
4
-
-
0037668882
-
Pharmacogenomics and the complexity of drug response
-
Müller M. Pharmacogenomics and the complexity of drug response. Int J Clin Pharmacol Ther 2003; 41: 231-40
-
(2003)
Int J Clin Pharmacol Ther
, vol.41
, pp. 231-240
-
-
Müller, M.1
-
5
-
-
26944454365
-
Improving pharmacotherapy outcomes by pharmacogenomics: From expectation to reality?
-
Vizirianakis IS. Improving pharmacotherapy outcomes by pharmacogenomics: from expectation to reality? Pharmacogenomics 2005; 6: 701-11
-
(2005)
Pharmacogenomics
, vol.6
, pp. 701-711
-
-
Vizirianakis, I.S.1
-
6
-
-
26944496229
-
Pharmacogenetics and the genetic basis of ADRs
-
Mann RD, Andrews EB, editors, West Sussex: John Wiley & Sons, Ltd
-
Manasco PK, Rieser P, Renegar G, et al. Pharmacogenetics and the genetic basis of ADRs. In: Mann RD, Andrews EB, editors. Pharmacovigilance. West Sussex: John Wiley & Sons, Ltd, 2002: 516-53
-
(2002)
Pharmacovigilance
, pp. 516-553
-
-
Manasco, P.K.1
Rieser, P.2
Renegar, G.3
-
7
-
-
0035033019
-
Pharmacogenomics: Unlocking the human genome for better drug therapy
-
McLeod HL, Evans WE. Pharmacogenomics: unlocking the human genome for better drug therapy. Annu Rev Pharmacol Toxicol 2001; 41: 101-21
-
(2001)
Annu Rev Pharmacol Toxicol
, vol.41
, pp. 101-121
-
-
McLeod, H.L.1
Evans, W.E.2
-
8
-
-
26944498056
-
Challenges in current drug delivery from the potential application of pharmacogenomics and personalized medicine in clinical practice
-
Vizirianakis IS. Challenges in current drug delivery from the potential application of pharmacogenomics and personalized medicine in clinical practice. Curr Drug Deliv 2004; 1: 73-80
-
(2004)
Curr Drug Deliv
, vol.1
, pp. 73-80
-
-
Vizirianakis, I.S.1
-
9
-
-
15244360703
-
Common gene polymorphisms, cancer progression and prognosis
-
Loktionov A. Common gene polymorphisms, cancer progression and prognosis. Cancer Let 2004; 208: 1-33
-
(2004)
Cancer Let
, vol.208
, pp. 1-33
-
-
Loktionov, A.1
-
10
-
-
0037346529
-
Cardiovascular pharmacogenomics: Current status, future prospects
-
Anderson JL, Carlquist JF, Horne BD, et al. Cardiovascular pharmacogenomics: current status, future prospects. J Cardiovasc Pharmacol Ther 2003; 8: 71-83
-
(2003)
J Cardiovasc Pharmacol Ther
, vol.8
, pp. 71-83
-
-
Anderson, J.L.1
Carlquist, J.F.2
Horne, B.D.3
-
11
-
-
0141851356
-
The application of functional genomics to Alzheimer's disease
-
Cacabelos R. The application of functional genomics to Alzheimer's disease. Pharmacogenomics 2004; 4: 597-621
-
(2004)
Pharmacogenomics
, vol.4
, pp. 597-621
-
-
Cacabelos, R.1
-
12
-
-
0344197480
-
Cancer pharmacogenetics: Polymorphisms, pathways and beyond
-
Ulrich CM, Robien K, Mcleod HL. Cancer pharmacogenetics: polymorphisms, pathways and beyond. Nat Rev Cancer 2003; 3: 912-20
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 912-920
-
-
Ulrich, C.M.1
Robien, K.2
Mcleod, H.L.3
-
13
-
-
14744293163
-
Pharmacogenetic approaches in the treatment of asthma
-
Sayers I, Hall IP. Pharmacogenetic approaches in the treatment of asthma. Curr Allergy Asthma Rep 2005; 5: 101-8
-
(2005)
Curr Allergy Asthma Rep
, vol.5
, pp. 101-108
-
-
Sayers, I.1
Hall, I.P.2
-
14
-
-
27744491843
-
Applications of AmpliChip™ CYP450
-
Jain KK. Applications of AmpliChip™ CYP450. Mol Diagn 2005; 9: 119-27
-
(2005)
Mol Diagn
, vol.9
, pp. 119-127
-
-
Jain, K.K.1
-
16
-
-
34548827472
-
-
Mayo Clinic to provide pharmacogenomics test to indicate risks of side effects from irinotecan [editorial]. Personalized Medicine 2006; 3: 15-8
-
Mayo Clinic to provide pharmacogenomics test to indicate risks of side effects from irinotecan [editorial]. Personalized Medicine 2006; 3: 15-8
-
-
-
-
17
-
-
0037399412
-
Tyrosine kinases as targets in cancer therapy: Successes and failures
-
Traxler P. Tyrosine kinases as targets in cancer therapy: successes and failures. Expert Opin Ther Targets 2003; 7: 215-34
-
(2003)
Expert Opin Ther Targets
, vol.7
, pp. 215-234
-
-
Traxler, P.1
-
18
-
-
0037315894
-
Disruption of differentiation in human cancer: AML shows the way
-
Tenen DG. Disruption of differentiation in human cancer: AML shows the way. Nature Rev Cancer 2003; 3: 89-101
-
(2003)
Nature Rev Cancer
, vol.3
, pp. 89-101
-
-
Tenen, D.G.1
-
19
-
-
0036566226
-
Differentiation plasticity of hematopoietic cells
-
Graf T. Differentiation plasticity of hematopoietic cells. Blood 2002; 99: 3089-101
-
(2002)
Blood
, vol.99
, pp. 3089-3101
-
-
Graf, T.1
-
22
-
-
0344255770
-
Mechanisms involved in the induced differentiation of leukemia cells
-
Tsiftsoglou AS, Pappas IS, Vizirianakis IS. Mechanisms involved in the induced differentiation of leukemia cells. Pharmacol Ther 2003; 100: 257-90
-
(2003)
Pharmacol Ther
, vol.100
, pp. 257-290
-
-
Tsiftsoglou, A.S.1
Pappas, I.S.2
Vizirianakis, I.S.3
-
23
-
-
33745955860
-
Impact of genetic diagnostics on drug development strategy
-
Million RP. Impact of genetic diagnostics on drug development strategy. Nat Rev Drug Discov 2006; 5: 459-62
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 459-462
-
-
Million, R.P.1
-
24
-
-
33751003260
-
Targeting transcription factors in cancer: Challenges and evolving strategies
-
Redell MS, Tweardy DJ. Targeting transcription factors in cancer: challenges and evolving strategies. Drug Discov Today: Technologies 2006; 3: 261-7
-
(2006)
Drug Discov Today: Technologies
, vol.3
, pp. 261-267
-
-
Redell, M.S.1
Tweardy, D.J.2
-
25
-
-
0036635291
-
Clivec (STI-571, imatinib), a rationally developed, targeted anticancer drug
-
Capdeville R, Buchdunger E, Zimmermann J, et al. Clivec (STI-571, imatinib), a rationally developed, targeted anticancer drug. Nat Rev Drug Discov 2002; 1: 493-502
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 493-502
-
-
Capdeville, R.1
Buchdunger, E.2
Zimmermann, J.3
-
26
-
-
2342629325
-
Imatinib (STI571) resistance in chronic myelogenous leukemia: Molecular basis of the underlying mechanisms and potential strategies for treatment
-
Cowan-Jacob SW, Guez V, Fendrich G, et al. Imatinib (STI571) resistance in chronic myelogenous leukemia: molecular basis of the underlying mechanisms and potential strategies for treatment. Mini Rev Med Chem 2004; 4: 285-99
-
(2004)
Mini Rev Med Chem
, vol.4
, pp. 285-299
-
-
Cowan-Jacob, S.W.1
Guez, V.2
Fendrich, G.3
-
27
-
-
18144418280
-
The impact of EGFR mutations on gefitinib sensitivity in non-small cell lung cancer
-
Suzuki T, Mitsudomi T, Hida T. The impact of EGFR mutations on gefitinib sensitivity in non-small cell lung cancer. Personalized Medicine 2004; 1: 27-34
-
(2004)
Personalized Medicine
, vol.1
, pp. 27-34
-
-
Suzuki, T.1
Mitsudomi, T.2
Hida, T.3
-
28
-
-
3142544162
-
The story of gefitinib, an EGFR kinase that works in lung cancer
-
Golsteyn RM. The story of gefitinib, an EGFR kinase that works in lung cancer. Drug Discov Today 2004; 9: 587
-
(2004)
Drug Discov Today
, vol.9
, pp. 587
-
-
Golsteyn, R.M.1
-
29
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004; 304: 1497-500
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
30
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004; 350: 2129-39
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
31
-
-
28444468144
-
EGFR inhibitors: What have we learned from the treatment of lung cancer? Nat Clin Pract
-
Giaccone G, Rodriguez JA. EGFR inhibitors: what have we learned from the treatment of lung cancer? Nat Clin Pract Oncol 2005; 2: 554-61
-
(2005)
Oncol
, vol.2
, pp. 554-561
-
-
Giaccone, G.1
Rodriguez, J.A.2
-
32
-
-
34548813749
-
-
American Association for Cancer Research. Single genetic assay could help physicians decide when to switch patients from Gleevec to Sutent [media release]. Philadelphia (PA): American Association for Cancer Research, 2006 Sep 14. Available from URL: http://www.aacr.org/home/public-media/newsreleases.aspx? d=651 [Accessed 2007 Jul 26]
-
American Association for Cancer Research. Single genetic assay could help physicians decide when to switch patients from Gleevec to Sutent [media release]. Philadelphia (PA): American Association for Cancer Research, 2006 Sep 14. Available from URL: http://www.aacr.org/home/public-media/newsreleases.aspx? d=651 [Accessed 2007 Jul 26]
-
-
-
-
33
-
-
33749238553
-
Discovery and development of sorafenib: A multikinase inhibitor for treating cancer
-
Wilhelm S, Carter C, Lynch M, et al. Discovery and development of sorafenib: a multikinase inhibitor for treating cancer. Nat Rev Drug Discov 2006; 5: 835-44
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 835-844
-
-
Wilhelm, S.1
Carter, C.2
Lynch, M.3
-
34
-
-
0034901493
-
The role of apoptosis in regulating hematopoietic stem cell numbers
-
Domen J. The role of apoptosis in regulating hematopoietic stem cell numbers. Apoptosis 2001; 6: 239-52
-
(2001)
Apoptosis
, vol.6
, pp. 239-252
-
-
Domen, J.1
-
36
-
-
33750064270
-
Identification of a molecular signature predictive to sensitivity to differentiation induction in acute myeloid leukemia
-
Tagliafico E, Tenedini E, Manfredini R, et al. Identification of a molecular signature predictive to sensitivity to differentiation induction in acute myeloid leukemia. Leukemia 2006; 20: 1751-8
-
(2006)
Leukemia
, vol.20
, pp. 1751-1758
-
-
Tagliafico, E.1
Tenedini, E.2
Manfredini, R.3
-
37
-
-
0347185032
-
Pharmacogenomics and 'individualized drug therapy': High expectations and disappointing achievements
-
Nebert DW, Nebert LJ, Vesell ES. Pharmacogenomics and 'individualized drug therapy': high expectations and disappointing achievements. Am J Pharmacogenomics 2003; 3: 361-70
-
(2003)
Am J Pharmacogenomics
, vol.3
, pp. 361-370
-
-
Nebert, D.W.1
Nebert, L.J.2
Vesell, E.S.3
-
38
-
-
4344684441
-
Pharmacogenetics and drug development: The path to safer and more effective drugs
-
Roses AD. Pharmacogenetics and drug development: the path to safer and more effective drugs. Nat Rev Genet 2004; 5: 645-56
-
(2004)
Nat Rev Genet
, vol.5
, pp. 645-656
-
-
Roses, A.D.1
-
39
-
-
0036596857
-
The impact of pharmacogenetics and pharmacogenomics on drug discovery
-
Lindpaintner K. The impact of pharmacogenetics and pharmacogenomics on drug discovery. Nat Rev Drug Discov 2002; 1: 463-9
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 463-469
-
-
Lindpaintner, K.1
-
40
-
-
0346024002
-
Therapeutic siRNAs
-
Sioud M. Therapeutic siRNAs. Trends Pharmacol Sci 2004; 25: 22-8
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 22-28
-
-
Sioud, M.1
-
41
-
-
33644856123
-
Epigenetic therapy of cancer: Past, present and future
-
Yoo CB. Jones PA. Epigenetic therapy of cancer: past, present and future. Nat Rev Drug Discov 2006; 5: 37-50
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 37-50
-
-
Yoo, C.B.1
Jones, P.A.2
-
42
-
-
1542782670
-
Use of pharmacogenetics and clinical factors to predict the maintenance dose of warfarin
-
Gage BF, Eby C, Milligan PE, et al. Use of pharmacogenetics and clinical factors to predict the maintenance dose of warfarin. Thromb Haemost 2004; 91: 87-94
-
(2004)
Thromb Haemost
, vol.91
, pp. 87-94
-
-
Gage, B.F.1
Eby, C.2
Milligan, P.E.3
-
43
-
-
23044438068
-
The pharmacogenetics of coumarin therapy
-
Voora D, McLeod HL, Eby C, et al. The pharmacogenetics of coumarin therapy. Pharmacogenomics 2005; 6: 503-13
-
(2005)
Pharmacogenomics
, vol.6
, pp. 503-513
-
-
Voora, D.1
McLeod, H.L.2
Eby, C.3
-
44
-
-
14944378525
-
Pharmacogenetics and ethnicity: More complexities of personalized prescribing
-
Hall IP. Pharmacogenetics and ethnicity: more complexities of personalized prescribing. Am J Respir Crit Care Med 2005; 171: 535-6
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 535-536
-
-
Hall, I.P.1
-
45
-
-
0036527287
-
Ethical perspectives on pharmacogenomic profiling in the drug development process
-
Issa AM. Ethical perspectives on pharmacogenomic profiling in the drug development process. Nat Rev Drug Discov 2002; 1: 300-8
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 300-308
-
-
Issa, A.M.1
-
46
-
-
14344260474
-
Will tomorrow's medicines work for everyone?
-
Tate SK, Goldstein DB. Will tomorrow's medicines work for everyone? Nat Genet 2004; 36: S34-42
-
(2004)
Nat Genet
, vol.36
-
-
Tate, S.K.1
Goldstein, D.B.2
-
47
-
-
29444455216
-
Confronting ethnicity-specific disease risk
-
Tang H. Confronting ethnicity-specific disease risk. Nat Genet 2006; 38: 13-5
-
(2006)
Nat Genet
, vol.38
, pp. 13-15
-
-
Tang, H.1
-
48
-
-
0037038230
-
Getting ready for gene-based medicine
-
Varmus H. Getting ready for gene-based medicine. N Engl J Med 2002; 347: 1526-7
-
(2002)
N Engl J Med
, vol.347
, pp. 1526-1527
-
-
Varmus, H.1
-
49
-
-
29144508395
-
Finding new drug targets in the 21st century
-
Lindsay MA. Finding new drug targets in the 21st century. Drug Discov Today 2005; 10: 1683-7
-
(2005)
Drug Discov Today
, vol.10
, pp. 1683-1687
-
-
Lindsay, M.A.1
-
50
-
-
0037421587
-
Pharmacogenetics in the laboratory and the clinic
-
Goldstein DB. Pharmacogenetics in the laboratory and the clinic. N Engl J Med 2003; 348: 553-6
-
(2003)
N Engl J Med
, vol.348
, pp. 553-556
-
-
Goldstein, D.B.1
-
51
-
-
0036164958
-
The fall and rise of in vivo pharmacology
-
In Vivo Pharmacology Training Group
-
In Vivo Pharmacology Training Group. The fall and rise of in vivo pharmacology. Trends Pharmacol Sci 2002; 23: 13-8
-
(2002)
Trends Pharmacol Sci
, vol.23
, pp. 13-18
-
-
-
52
-
-
33645098226
-
What is the future role of pharmacologists in the pharmaceutical industry?
-
Collis MG. What is the future role of pharmacologists in the pharmaceutical industry? Trends Pharmacol Sci 2006; 27: 126-9
-
(2006)
Trends Pharmacol Sci
, vol.27
, pp. 126-129
-
-
Collis, M.G.1
-
53
-
-
33645107562
-
Challenges facing pharmacology: The in vivo situation
-
Walker MJA, Soh MLM. Challenges facing pharmacology: the in vivo situation. Trends Pharmacol Sci 2006; 27: 125-6
-
(2006)
Trends Pharmacol Sci
, vol.27
, pp. 125-126
-
-
Walker, M.J.A.1
Soh, M.L.M.2
-
54
-
-
0346728473
-
Systematic genome-wide screens of gene function
-
Carpenter AE, Sabatini DM. Systematic genome-wide screens of gene function. Nat Rev Genet 2004; 5: 11-22
-
(2004)
Nat Rev Genet
, vol.5
, pp. 11-22
-
-
Carpenter, A.E.1
Sabatini, D.M.2
-
55
-
-
3543068702
-
Microarray platforms-comparisons and contrasts
-
Hardiman G. Microarray platforms-comparisons and contrasts. Pharmacogenomics 2004; 5: 487-502
-
(2004)
Pharmacogenomics
, vol.5
, pp. 487-502
-
-
Hardiman, G.1
-
56
-
-
0042468096
-
Impact of drug transporter studies on drug discovery and development
-
Mizuno N, Niwa T, Yotsumoto Y, et al. Impact of drug transporter studies on drug discovery and development. Pharmacol Rev 2003; 55: 425-61
-
(2003)
Pharmacol Rev
, vol.55
, pp. 425-461
-
-
Mizuno, N.1
Niwa, T.2
Yotsumoto, Y.3
-
57
-
-
0346728729
-
The ABCs of drug transport in intestine and live: Efflux proteins limiting drug absorption and bioavailability
-
Chan LMS, Lowes S, Hirst BH. The ABCs of drug transport in intestine and live: efflux proteins limiting drug absorption and bioavailability. Eur J Pharm Sci 2004; 21: 25-51
-
(2004)
Eur J Pharm Sci
, vol.21
, pp. 25-51
-
-
Chan, L.M.S.1
Lowes, S.2
Hirst, B.H.3
-
58
-
-
1342344851
-
Transporters and renal drug elimination
-
Lee W, Kim RB. Transporters and renal drug elimination. Annu Rev Pharmacol Toxicol 2004; 44: 137-66
-
(2004)
Annu Rev Pharmacol Toxicol
, vol.44
, pp. 137-166
-
-
Lee, W.1
Kim, R.B.2
-
59
-
-
33745216665
-
Designing better drugs: Predicting cytochrome P450 metabolism
-
De Groot MJ. Designing better drugs: predicting cytochrome P450 metabolism. Drug Discov Today 2006; 11: 601-6
-
(2006)
Drug Discov Today
, vol.11
, pp. 601-606
-
-
De Groot, M.J.1
-
60
-
-
1542327276
-
Predicting undesirable drug interactions with promiscuous proteins in silico
-
Ekins S. Predicting undesirable drug interactions with promiscuous proteins in silico. Drug Discov Today 2004; 9: 276-85
-
(2004)
Drug Discov Today
, vol.9
, pp. 276-285
-
-
Ekins, S.1
-
61
-
-
23944452158
-
Using genotyping to predict responses to anti-hypertensive treatment
-
Kurland L, Lind L, Melhus H. Using genotyping to predict responses to anti-hypertensive treatment. Trends Pharmacol Sci 2005; 26: 443-7
-
(2005)
Trends Pharmacol Sci
, vol.26
, pp. 443-447
-
-
Kurland, L.1
Lind, L.2
Melhus, H.3
-
62
-
-
18344387906
-
Studies on genes and hypertension: A daunting task
-
Saavedra JM. Studies on genes and hypertension: a daunting task. J Hypertension 2005; 23: 929-32
-
(2005)
J Hypertension
, vol.23
, pp. 929-932
-
-
Saavedra, J.M.1
-
63
-
-
0242640305
-
Pharmacogenomics and reducing the frequency of adverse drug events
-
O'Kane DJ, Weinshilboum RM, Moyer TP. Pharmacogenomics and reducing the frequency of adverse drug events. Pharmacogenomics 2003; 4: 1-4
-
(2003)
Pharmacogenomics
, vol.4
, pp. 1-4
-
-
O'Kane, D.J.1
Weinshilboum, R.M.2
Moyer, T.P.3
-
64
-
-
22044451327
-
Ontologies and semantic data integration
-
Gardner SP. Ontologies and semantic data integration. Drug Discov Today 2005; 10: 1001-7
-
(2005)
Drug Discov Today
, vol.10
, pp. 1001-1007
-
-
Gardner, S.P.1
-
65
-
-
33744733079
-
The promise of personalized medicine: A conversation with Michael Svinte
-
Millenson ML. The promise of personalized medicine: a conversation with Michael Svinte. Health Affairs 2006; 25: w54-60
-
(2006)
Health Affairs
, vol.25
-
-
Millenson, M.L.1
-
67
-
-
27144548842
-
Automation and validation of DNA-banking systems
-
Thornton M, Gladwin A, Payne R, et al. Automation and validation of DNA-banking systems. Drug Discov Today 2005; 10: 1369-75
-
(2005)
Drug Discov Today
, vol.10
, pp. 1369-1375
-
-
Thornton, M.1
Gladwin, A.2
Payne, R.3
-
68
-
-
4544304098
-
A drug database model as a central element for computer-supported dose adjustment within a CPOE system
-
Martin P, Haefeli WE, Martin-Facklam M. A drug database model as a central element for computer-supported dose adjustment within a CPOE system. J Amer Med Inform Assoc 2004; 11: 427-32
-
(2004)
J Amer Med Inform Assoc
, vol.11
, pp. 427-432
-
-
Martin, P.1
Haefeli, W.E.2
Martin-Facklam, M.3
-
69
-
-
14844323703
-
HYGEIAnet: The integrated regional health information network of Crete
-
Orphanoudakis S. HYGEIAnet: the integrated regional health information network of Crete. Stud Health Technol Inform 2004; 100: 66-78
-
(2004)
Stud Health Technol Inform
, vol.100
, pp. 66-78
-
-
Orphanoudakis, S.1
-
70
-
-
33750631634
-
A European survey on the possibilities and obstacles of electronic prescriptions in cross-border healthcare
-
Mäkinen M, Forsström J, Äärimaa M, et al. A European survey on the possibilities and obstacles of electronic prescriptions in cross-border healthcare. Telemed J E Health 2006; 12: 484-9
-
(2006)
Telemed J E Health
, vol.12
, pp. 484-489
-
-
Mäkinen, M.1
Forsström, J.2
Äärimaa, M.3
-
71
-
-
33645097794
-
Tackling the need to teach integrative pharmacology and physiology: Problems and ways forward
-
British Pharmacological Society and the Physiological Society
-
British Pharmacological Society and the Physiological Society. Tackling the need to teach integrative pharmacology and physiology: problems and ways forward. Trends Pharmacol Sci 2006; 27: 130-3
-
(2006)
Trends Pharmacol Sci
, vol.27
, pp. 130-133
-
-
-
72
-
-
33744528341
-
Pharmacovigilance in a genomic era
-
Farahani P, Levine M. Pharmacovigilance in a genomic era. Pharmacogenomics J 2006; 6: 158-61
-
(2006)
Pharmacogenomics J
, vol.6
, pp. 158-161
-
-
Farahani, P.1
Levine, M.2
-
73
-
-
33750284204
-
Protecting the health of the public: Institute of Medicine recommendations on drug safety
-
Psaty BM, Burke SP. Protecting the health of the public: Institute of Medicine recommendations on drug safety. N Engl J Med 2006; 355: 1753-5
-
(2006)
N Engl J Med
, vol.355
, pp. 1753-1755
-
-
Psaty, B.M.1
Burke, S.P.2
-
75
-
-
7644233594
-
Molecular genetics and genomics of heart failure
-
Liew C-C, Dzau VJ. Molecular genetics and genomics of heart failure. Nat Rev Genet 2004; 5: 811-25
-
(2004)
Nat Rev Genet
, vol.5
, pp. 811-825
-
-
Liew, C.-C.1
Dzau, V.J.2
-
76
-
-
0344492207
-
Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: Evidence for a provisional safety margin in drug development
-
Redfern WS, Carlsson L, Davis AS, et al. Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development. Cardiovasc Res 2003; 58: 32-45
-
(2003)
Cardiovasc Res
, vol.58
, pp. 32-45
-
-
Redfern, W.S.1
Carlsson, L.2
Davis, A.S.3
-
77
-
-
0037978018
-
Genetics and arrhythmias
-
Roberts R, Brugada R. Genetics and arrhythmias. Annu Rev Med 2003; 54: 257-67
-
(2003)
Annu Rev Med
, vol.54
, pp. 257-267
-
-
Roberts, R.1
Brugada, R.2
-
78
-
-
13844254976
-
Predictive in silico modeling for hERG channel blockers
-
Aronov AM. Predictive in silico modeling for hERG channel blockers. Drug Discov Today 2005; 10: 149-55
-
(2005)
Drug Discov Today
, vol.10
, pp. 149-155
-
-
Aronov, A.M.1
-
79
-
-
29144494740
-
Genetic testing in the long QT syndrome: Development and validation of an efficient approach to genotyping in clinical practice
-
Napolitano C, Priori SG, Schwartz PJ, et al. Genetic testing in the long QT syndrome: development and validation of an efficient approach to genotyping in clinical practice. J Amer Med Assoc 2005; 294: 2975-80
-
(2005)
J Amer Med Assoc
, vol.294
, pp. 2975-2980
-
-
Napolitano, C.1
Priori, S.G.2
Schwartz, P.J.3
-
81
-
-
26944438354
-
Drugs, QTc interval prolongation and final ICH E14 guideline: An important milestone with challenges ahead
-
Shah RR. Drugs, QTc interval prolongation and final ICH E14 guideline: an important milestone with challenges ahead. Drug Saf 2005; 28: 1009-28
-
(2005)
Drug Saf
, vol.28
, pp. 1009-1028
-
-
Shah, R.R.1
-
82
-
-
0036124608
-
Pharmaceutical education in the wake of genomic technologies for drug development and personalized medicine
-
Vizirianakis IS. Pharmaceutical education in the wake of genomic technologies for drug development and personalized medicine. Eur J Pharm Sci 2002; 15: 243-50
-
(2002)
Eur J Pharm Sci
, vol.15
, pp. 243-250
-
-
Vizirianakis, I.S.1
-
83
-
-
0037333738
-
Education: Teaching pharmacogenomics to prepare future physicians and researchers for personalized medicine
-
Gurwitz D, Weizman A, Rehavi M. Education: teaching pharmacogenomics to prepare future physicians and researchers for personalized medicine. Trends Pharmacol Sci 2003; 24: 122-5
-
(2003)
Trends Pharmacol Sci
, vol.24
, pp. 122-125
-
-
Gurwitz, D.1
Weizman, A.2
Rehavi, M.3
-
84
-
-
23644449909
-
Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education
-
Gurwitz D, Lunshof JE, Dedoussis G, et al. Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education. Pharmacogenomics J 2005; 5: 221-5
-
(2005)
Pharmacogenomics J
, vol.5
, pp. 221-225
-
-
Gurwitz, D.1
Lunshof, J.E.2
Dedoussis, G.3
-
86
-
-
34548860497
-
-
Cambridge Healthcare Institute. Pharmaceutical genomics glossary & taxonomy: evolving terminology for emerging technologies [online]. Available from URL: http://www.genomicglossaries.com/content/genomics_glossary.asp [Accessed 2007 Aug 14]
-
Cambridge Healthcare Institute. Pharmaceutical genomics glossary & taxonomy: evolving terminology for emerging technologies [online]. Available from URL: http://www.genomicglossaries.com/content/genomics_glossary.asp [Accessed 2007 Aug 14]
-
-
-
-
87
-
-
28444467388
-
Pharmacogenomics and drug development
-
Guo Y, Shafer S, Weller P, et al. Pharmacogenomics and drug development. Pharmacogenomics 2005; 6: 857-64
-
(2005)
Pharmacogenomics
, vol.6
, pp. 857-864
-
-
Guo, Y.1
Shafer, S.2
Weller, P.3
-
88
-
-
33745846746
-
Understanding our drugs and our diseases
-
Guo Y, Weller P, Allard J, et al. Understanding our drugs and our diseases. Proc Am Thorac Soc 2006; 3: 409-12
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 409-412
-
-
Guo, Y.1
Weller, P.2
Allard, J.3
-
89
-
-
29544449443
-
Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 2D6 and CYP450 2C19
-
Leon De J, Armstrong SC, Cozza KL. Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 2D6 and CYP450 2C19. Psychosomatics 2006; 47: 75-85
-
(2006)
Psychosomatics
, vol.47
, pp. 75-85
-
-
Leon, D.J.1
Armstrong, S.C.2
Cozza, K.L.3
-
90
-
-
33751329250
-
Global variation in copy number in the human genome
-
Redon R, Ishikawa S, Fitch KR, et al. Global variation in copy number in the human genome. Nature 2006; 444: 444-54
-
(2006)
Nature
, vol.444
, pp. 444-454
-
-
Redon, R.1
Ishikawa, S.2
Fitch, K.R.3
|