Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia

Journal of Biological Chemistry

Volumn 282, Issue 36, 2007, Pages 26089-26100

  Knecht, Wolfgang ^a   Cottrell, Graeme S ^b   Amadesi, Silvia ^b   Mohlin, Johanna ^a   Skåregärde, Anita ^a   Gedda, Karin ^a   Peterson, Anders ^a   Chapman, Kevin ^c   Hollenberg, Morley D ^c   Vergnolle, Nathalie ^c,d,e   Bunnett, Nigel W ^b  

^a ASTRAZENECA R AND D   (Sweden)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALGARY   (Canada)

^d INSERM   (France)

^e UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE INFILTRATION; NEUROGENIC INFLAMMATION;

BACTERIA; DEGRADATION; NEUROLOGY; PROTEINS; PURIFICATION;

BIOMEDICAL ENGINEERING;

APROTININ; ENZYME PRECURSOR; PROTEIN P23; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; TRYPSIN; TRYPSIN INHIBITOR; TRYPSIN IV; TRYPSINOGEN; UNCLASSIFIED DRUG;

ALLODYNIA; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CELL INFILTRATION; EDEMA; ESCHERICHIA COLI; GENETIC TRANSFECTION; GRANULOCYTE; HYPERALGESIA; MALE; MOUSE; NOCICEPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; RAT; RECEPTOR BINDING; SEQUENCE ANALYSIS; SPINAL GANGLION;

ANIMALS; APROTININ; CALCIUM SIGNALING; CAPSAICIN; EDEMA; ENTEROPEPTIDASE; GANGLIA, SPINAL; GRANULOCYTES; HUMANS; HYPERALGESIA; INFLAMMATION; MALE; MICE; MICE, KNOCKOUT; NOCICEPTORS; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, PAR-1; RECEPTOR, PAR-2; RECEPTORS, PROTEINASE-ACTIVATED; RECEPTORS, THROMBIN; RECOMBINANT PROTEINS; TRYPSIN; TRYPSIN INHIBITORS;

ESCHERICHIA COLI; GLYCINE MAX; MUS; RATTUS;

EID: 34548829096     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M703840200     Document Type: Article

References (58)

1. Emi, M., Nakamura, Y., Ogawa, M., Yamamoto, T., Nishide, T., Mori, T., and Matsubara, K. (1986) Gene (Amst.) 41, 305-310
2. Nyaruhucha, C. N., Kito, M., and Fukuoka, S. I. (1997) J. Biol. Chem. 272, 10573-10578
3. Wiegand, U., Corbach, S., Minn, A., Kang, J., and Muller-Hill, B. (1993) Gene (Amst.) 136, 167-175
4. Szmola, R., Kukor, Z., and Sahin-Toth, M. (2003) J. Biol. Chem. 278, 48580-48589
5. Schick, J., Kern, H., and Scheele, G. (1984) J. Cell Biol. 99, 1569-1574
6. Kunitz, M. (1939) J. Gen. Physiol. 22, 429-446
7. Yamashina, I. (1956) Acta Chem. Scand. 10, 739-743
8. Rowen, L., Williams, E., Glusman, G., Linardopoulou, E., Friedman, C., Ahearn, M. E., Seto, J., Boysen, C., Qin, S., Wang, K., Kaur, A., Bloom, S., Hood, L., and Trask, B. J. (2005) Mol. Biol. Evol. 22, 1712-1720
9. Rinderknecht, H., Renner, I. G., Abramson, S. B., and Carmack, C. (1984) Gastroenterology 86, 681-692
10. Cottrell, G. S., Amadesi, S., Grady, E. F., and Bunnett, N. W. (2004) J. Biol. Chem. 279, 13532-13539
11. Gallatz, K., Medveczky, P., Nemeth, P., Szilagyi, L., Graf, L., and Palkovits, M. (2007) Ideggyogy Sz. 60, 118-123
12. Toth, J., Siklodi, E., Medveczky, P., Gallatz, K., Nemeth, P., Szilagyi, L., Graf, L., and Palkovits, M. (2007) Neurochem. Res. 32, 1423-1433
13. Nemeth, A. L., Medveczky, P., Toth, J., Siklodi, E., Schlett, K., Patthy, A., Palkovits, M., Ovadi, J., Tokesi, N., Nemeth, P., Szilagyi, L., and Graf, L. (2007) FEBS J. 274, 1610-1620
14. Sahin-Toth, M. (2005) Protein Pept. Lett 12, 457-464
15. Fukuoka, S., and Nyaruhucha, C. M. (2002) Biochim. Biophys. Acta 1588, 106-112
16. Diederichs, S., Bulk, E., Steffen, B., Ji, P., Tickenbrock, L., Lang, K., Zanker, K. S., Metzger, R., Schneider, P. M., Gerke, V., Thomas, M., Berdel, W. E., Serve, H., and Muller-Tidow, C. (2004) Cancer Res. 64, 5564-5569
17. Marsit, C. J., Karagas, M. R., Danaee, H., Liu, M., Andrew, A., Schned, A., Nelson, H. H., and Kelsey, K. T. (2006) Carcinogenesis 27, 112-116
18. Yamashita, K., Mimori, K., Inoue, H., Mori, M., and Sidransky, D. (2003) Cancer Res. 63, 6575-6578
19. Minn, A., Schubert, M., Neiss, W. F., and Muller-Hill, B. (1998) Glia 22, 338-347
20. Medveczky, P., Antal, J., Patthy, A., Kekesi, K., Juhasz, G., Szilagyi, L., and Graf, L. (2006) FEBS Lett. 580, 545-552
21. Ossovskaya, V. S., and Bunnett, N. W. (2004) Physiol. Rev. 84, 579-621
22. Nystedt, S., Emilsson, K., Wahlestedt, C., and Sundelin, J. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 9208-9212
23. Bohm, S. K., Kong, W., Bromme, D., Smeekens, S. P., Anderson, D. C., Connolly, A., Kahn, M., Nelken, N. A., Coughlin, S. R., Payan, D. G., and Bunnett, N. W. (1996) Biochem. J. 314, 1009-1016
24. Vu, T. K., Hung, D. T., Wheaton, V. I., and Coughlin, S. R. (1991) Cell 64, 1057-1068
25. Blackhart, B. D., Emilsson, K., Nguyen, D., Teng, W., Martelli, A. J., Nystedt, S., Sundelin, J., and Scarborough, R. M. (1996) J. Biol. Chem. 271, 16466-16471
26. Kawabata, A., Saifeddine, M., Al-Ani, B., Leblond, L., and Hollenberg, M. D. (1999) J. Pharmacol. Exp. Ther. 288, 358-370
27. Loew, D., Perrault, C., Morales, M., Moog, S., Ravanat, C., Schuhler, S., Arcone, R., Pietropaolo, C., Cazenave, J. P., van Dorsselaer, A., and Lanza, F. (2000) Biochemistry 39, 10812-10822
28. Kahn, M. L., Zheng, Y. W., Huang, W., Bigornia, V., Zeng, D., Moff, S., Farese, R. V., Jr., Tam, C., and Coughlin, S. R. (1998) Nature 394, 690-694
29. Xu, W. F., Andersen, H., Whitmore, T. E., Presnell, S. R., Yee, D. P., Ching, A., Gilbert, T., Davie, E. W., and Foster, D. C. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6642-6646
30. Grishina, Z., Ostrowska, E., Halangk, W., Sahin-Toth, M., and Reiser, G. (2005) Br. J. Pharmacol. 146, 990-999
31. Wang, Y., Luo, W., Wartmann, T., Halangk, W., Sahin-Toth, M., and Reiser, G. (2006) J. Neurochem. 99, 759-769
32. Steinhoff, M., Vergnolle, N., Young, S. H., Tognetto, M., Amadesi, S., Ennes, H. S., Trevisani, M., Hollenberg, M. D., Wallace, J. L., Caughey, G. H., Mitchell, S. E., Williams, L. M., Geppetti, P., Mayer, E. A., and Bunnett, N. W. (2000) Nat. Med. 6, 151-158
33. de Garavilla, L., Vergnolle, N., Young, S. H., Ennes, H., Steinhoff, M., Ossovskaya, V. S., D'Andrea, M. R., Mayer, E. A., Wallace, J. L., Hollenberg, M. D., Andrade-Gordon, P., and Bunnett, N. W. (2001) Br. J. Pharmacol. 133, 975-987
34. Vergnolle, N., Bunnett, N. W., Sharkey, K. A., Brussee, V., Compton, S. J., Grady, E. F., Cirino, G., Gerard, N., Basbaum, A. I., Andrade-Gordon, P., Hollenberg, M. D., and Wallace, J. L. (2001) Nat. Med. 7, 821-826
35. Kawabata, A., Kawao, N., Kuroda, R., Tanaka, A., Itoh, H., and Nishikawa, H. (2001) Neuroreport. 12, 715-719
36. Amadesi, S., Nie, J., Vergnolle, N., Cottrell, G. S., Grady, E. F., Trevisani, M., Manni, C., Geppetti, P., McRoberts, J. A., Ennes, H., Davis, J. B., Mayer, E. A., and Bunnett, N. W. (2004) J. Neurosci. 24, 4300-4312
37. Amadesi, S., Cottrell, G. S., Divino, L., Chapman, K., Grady, E. F., Bautista, F., Karanjia, R., Barajas-Lopez, C., Vanner, S., Vergnolle, N., and Bunnett, N. W. (2006) J. Physiol. 575, 555-571
38. Grant, A. D., Cottrell, G. S., Amadesi, S., Trevisani, M., Nicoletti, P., Materazzi, S., Altier, C., Cenac, N., Zamponi, G. W., Bautista-Cruz, F., Lopez, C. B., Joseph, E. K., Levine, J. D., Liedtke, W., Vanner, S., Vergnolle, N., Geppetti, P., and Bunnett, N. W. (2007) J. Physiol. 578, 715-733
39. Darrow, A. L., Fung-Leung, W. P., Ye, R. D., Santulli, R. J., Cheung, W. M., Derian, C. K., Burns, C. L., Damiano, B. P., Zhou, L., Keenan, C. M., Peterson, P. A., and Andrade-Gordon, P. (1996) Thromb. Haemost. 76, 860-866
40. Damiano, B. P., Cheung, W. M., Santulli, R. J., Fung-Leung, W. P., Ngo, K., Ye, R. D., Darrow, A. L., Derian, C. K., de Garavilla, L., and Andrade-Gordon, P. (1999) J. Pharmacol. Exp. Ther. 288, 671-678
41. Oikonomopoulou, K., Hansen, K. K., Saifeddine, M., Tea, I., Blaber, M., Blaber, S. I., Scarisbrick, I., Andrade-Gordon, P., Cottrell, G. S., Bunnett, N. W., Diamandis, E. P., and Hollenberg, M. D. (2006) J. Biol. Chem. 281, 32095-32112
42. Bohm, S. K., Khitin, L. M., Grady, E. F., Aponte, G., Payan, D. G., and Bunnett, N. W. (1996) J. Biol. Chem. 271, 22003-22016
43. Asfaha, S., Brussee, V., Chapman, K., Zochodne, D. W., and Vergnolle, N. (2002) Br. J. Pharmacol. 135, 1101-1106
44. Caterina, M. J., Schumacher, M. A., Tominaga, M., Rosen, T. A., Levine, J. D., and Julius, D. (1997) Nature 389, 816-824
45. Caterina, M. J., Leffler, A., Malmberg, A. B., Martin, W. J., Trafton, J., Petersen-Zeitz, K. R., Koltzenburg, M., Basbaum, A. I., and Julius, D. (2000) Science 288, 306-313
46. Davis, J. B., Gray, J., Gunthorpe, M. J., Hatcher, J. P., Davey, P. T., Overend, P., Harries, M. H., Latcham, J., Clapham, C., Atkinson, K., Hughes, S. A., Rance, K., Grau, E., Harper, A. J., Pugh, P. L., Rogers, D. C., Bingham, S., Randall, A., and Sheardown, S. A. (2000) Nature 405, 183-187
47. Katona, G., Berglund, G. I., Hajdu, J., Graf, L., and Szilagyi, L. (2002) J. Mol. Biol. 315, 1209-1218
48. Szilagyi, L., Kenesi, E., Katona, G., Kaslik, G., Juhasz, G., and Graf, L. (2001) J. Biol. Chem. 276, 24574-24580
49. Szepessy, E., and Sahin-Toth, M. (2006) FEBS J. 273, 2942-2954
50. Camerer, E., Huang, W., and Coughlin, S. R. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 5255-5260
51. Riewald, M., Kravchenko, V. V., Petrovan, R. J., O'Brien, P. J., Brass, L. F., Ulevitch, R. J., and Ruf, W. (2001) Blood 97, 3109-3116
52. Compton, S. J., Renaux, B., Wijesuriya, S. J., and Hollenberg, M. D. (2001) Br. J. Pharmacol. 134, 705-718
53. Compton, S. J., Sandhu, S., Wijesuriya, S. J., and Hollenberg, M. D. (2002) Biochem. J. 368, 495-505
54. Nakayama, T., Hirano, K., Shintani, Y., Nishimura, J., Nakatsuka, A., Kuga, H., Takahashi, S., and Kanaide, H. (2003) Br. J. Pharmacol. 138, 121-130
55. Cenac, N., Garcia-Villar, R., Ferrier, L., Larauche, M., Vergnolle, N., Bunnett, N. W., Coelho, A. M., Fioramonti, J., and Bueno, L. (2003) J. Immunol. 170, 4296-4300
56. Nguyen, C., Coelho, A. M., Grady, E., Compton, S. J., Wallace, J. L., Hollenberg, M. D., Cenac, N., Garcia-Villar, R., Bueno, L., Steinhoff, M., Bunnett, N. W., and Vergnolle, N. (2003) Can J. Physiol. Pharmacol. 81, 920-927
57. Coelho, A. M., Vergnolle, N., Guiard, B., Fioramonti, J., and Bueno, L. (2002) Gastroenterology 122, 1035-1047
58. Cottrell, G. S., Amadesi, S., Pikios, S., Camerer, E., Willardsen, J. A., Murphy, B. R., Caughey, G. H., Wolters, P. J., Coughlin, S. R., Peterson, A., Knecht, W., Pothoulakis, C., Bunnett, N. W., and Grady, E. F. (2007) Gastroenterology 132, 2422-2437