Unproductive cleavage and the inactivation of protease-activated receptor-1 by trypsin in vascular endothelial cells

British Journal of Pharmacology

Volumn 138, Issue 1, 2003, Pages 121-130

  Nakayama, Tetsuzo ^a   Hirano, Katsuya ^a   Shintani, Yoshinobu ^a   Nishimura, Junji ^a   Nakatsuka, Akio ^a   Kuga, Hirotaka ^a   Takahashi, Shosuke ^a   Kanaide, Hideo ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Endothelial cells; Protease activated receptor; Thrombin; Trypsin

Indexed keywords

BRADYKININ; CALCIUM; FURA 2; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; SUBSTANCE P; THROMBIN; TRYPSIN;

ANIMAL CELL; ARTICLE; FLUOROMETRY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RECEPTOR AFFINITY; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SWINE; VASCULAR ENDOTHELIUM;

ANIMALS; CELL DIVISION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; HUMANS; RATS; RECEPTOR, PAR-1; RECEPTORS, THROMBIN; SWINE; TRYPSIN;

EID: 0037278823     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705008     Document Type: Article

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