Induction of apoptosis by Uncaria tomentosa through reactive oxygen species production, cytochrome c release, and caspases activation in human leukemia cells

Food and Chemical Toxicology

Volumn 45, Issue 11, 2007, Pages 2206-2218

  Cheng, An Chin ^a   Jian, Cheng Bang ^b   Huang, Yu Ting ^b   Lai, Ching Shu ^b,c   Hsu, Ping Chi ^b   Pan, Min Hsiung ^b  

^a TOKO UNIVERSITY   (Taiwan)

^b NATIONAL KAOHSIUNG UNIVERSITY OF APPLIED SCIENCES   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Bcl 2 family; Caspase; Cat's claw ethyl acetate extracts (CC EA); DNA fragmentation; Fas

Indexed keywords

ACETIC ACID ETHYL ESTER; BUTANOL; CASPASE 3; CYTOCHROME C; DNA; DNA FRAGMENTATION FACTOR 45; FAS ANTIGEN; HEXANE; METHANOL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLSERINE; PROCASPASE 8; PROTEIN BAX; PROTEIN BCL XL; PROTEIN BID; PROTEIN MCL 1; REACTIVE OXYGEN METABOLITE; UNCARIA TOMENTOSA EXTRACT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STRAIN HL 60; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA DEGRADATION; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; UNCARIA TOMENTOSA;

ANTIGENS, CD95; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASES; CAT'S CLAW; CELL MEMBRANE; CYCLIN-DEPENDENT KINASE INHIBITOR PROTEINS; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GENES, BCL-2; HL-60 CELLS; HUMANS; LEUKEMIA; PHOSPHATIDYLSERINES; PLANT EXTRACTS; POLY(ADP-RIBOSE) POLYMERASES; PROTEINS; REACTIVE OXYGEN SPECIES;

UNCARIA TOMENTOSA;

EID: 34548820421     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2007.05.016     Document Type: Article

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